Search results for "vaihdevuodet"

Menopausal symptoms and cardiometabolic risk factors in middle-aged women : A cross-sectional and longitudinal study with 4-year follow-up

2023

Objective To study associations of menopausal symptoms with cardiometabolic risk factors. Study design A cross-sectional and longitudinal study of a representative population sample of 1393 women aged 47–55 years with a sub-sample of 298 followed for four years. The numbers of vasomotor, psychological, somatic or pain, and urogenital menopausal symptoms were ascertained at baseline through self-report. Their associations with cardiometabolic risk factors were studied using linear regression and linear mixed-effect models. Models were adjusted for age, menopausal status, body mass index, the use of hormonal preparations, education, smoking, and alcohol consumption. Main outcome measures Card…

Total and regional body adiposity increases during menopause : evidence from a follow‐up study

2022

For women, menopausal transition is a time of significant hormonal changes, which may contribute to altered body composition and regional adipose tissue accumulation. Excess adiposity, and especially adipose tissue accumulation in the central body region, increases women's risk of cardiovascular and metabolic conditions and affects physical functioning. We investigated the associations between menopausal progression and total and regional body adiposity measured with dual-energy X-ray absorptiometry and computed tomography in two longitudinal cohort studies of women aged 47–55 (n = 230 and 148, mean follow-up times 1.3 ± 0.7 and 3.9 ± 0.2 years, mean baseline BMI 25.5 kg/m2). We also examin…

Influences of muscle, fat and hormones on bone development in women : a cross-sectional and longitudinal study spanning three generations

2011

Role of Menopausal Transition and Physical Activity in Loss of Lean and Muscle Mass : A Follow-Up Study in Middle-Aged Finnish Women

2020

In midlife, women experience hormonal changes due to menopausal transition. A decrease especially in estradiol has been hypothesized to cause loss of muscle mass. This study investigated the effect of menopausal transition on changes in lean and muscle mass, from the total body to the muscle fiber level, among 47–55-year-old women. Data were used from the Estrogenic Regulation of Muscle Apoptosis (ERMA) study, where 234 women were followed from perimenopause to early postmenopause. Hormone levels (estradiol and follicle stimulating hormone), total and regional body composition (dual-energy X-ray absorptiometry (DXA) and computed tomography (CT) scans), physical activity level (self-reported…

Liikuntaintervention ja estrogeenikorvaushoidon vaikutus 50-57-vuotiaiden naisten aerobiseen kuntoon

1998

Uni ja kardiometabolia : vaihdevuosi-ikäisten naisten unen laadun yhteys sokeri- ja rasva-aineenvaihduntaan ja leptiinitasoihin

2017

Unen laatu heikkenee vaihdevuosien aikana. Heikentynyt unen laatu on yhteydessä sokeri- ja rasva-aineenvaihdunnan häiriöihin. Tämän pro gradu-tutkielman tarkoituksena oli selvittää vaihdevuosi-ikäisten naisten unen laadun yhteyttä kardiometabolisiin riskitekijöihin. Tutkielma perustuu Estrogeeni, vaihdevuodet ja toimintakyky (ERMA) -tutkimuksen aineistoon. Osallistujat poimittiin satunnaisotannalla väestörekisteristä Jyväskylän ja sen lähikuntien 47–54 -vuotiaista naisista (n=6886). Mukaan valittiin ne sisäänottokriteerit täyttävät naiset, jotka vastasivat tutkimuksen alkumittauskyselyyn ja joilta terveydentilaa selvittävän haastattelun sekä laboratoriomittausten jälkeen saatiin luotettavas…

Female reproductive factors are associated with objectively measured physical activity in middle-aged women

2017

Physical activity improves health and may delay the onset of several chronic diseases. For women in particular, the rate of these diseases accelerates at middle age; therefore it is important to identify the determinants of health-enhancing physical activity during midlife in this population. In this study, we focused on determinants that are unique to the female sex, such as childbearing and menopause. The main objective was to characterize the level of physical activity and differences between active and inactive middle-aged Finnish women. In addition, we examined the association of physical activity with female reproductive factors at midlife. The study population consisted of 647 women …

Physical Performance During the Menopausal Transition and the Role of Physical Activity

2020

Abstract Background To examine longitudinal changes in physical performance during the menopausal transition and the role of physical activity (PA) in these changes. Methods Based on follicle-stimulating hormone levels and bleeding diaries, women (47–55 years) were classified as early (n = 89) and late perimenopausal (n = 143) and followed prospectively until postmenopausal status, with mean duration of 17.5 and 13.8 months, respectively. Physical performance was measured by handgrip force, knee extension torque, vertical jumping height, maximal walking speed, and 6-minute walking distance. Physical activity was self-reported and categorized as inactive, low, medium, and high. Longitudinal …

Hormonikorvaushoidon ja fyysisen aktiivisuuden yhteys kehon koostumukseen postmenopausaalisilla naisilla : 10 vuoden seurantatutkimus

2011

Tämän tutkielman tavoitteena oli selvittää, onko estrogeenia sisältävällä hormonikorvaushoidolla (HRT) ja fyysisellä aktiivisuudella (PA) yhteyttä ja yhteisvaikutusta kehon koostumukseen vaihdevuosi-ikäisillä naisilla. Selvityksen kohteena olivat myös HRT- ja liikuntaintervention vaikutusten säilyminen kehon koostumuksessa sekä fyysisessä aktiivisuudessa tapahtuvat muutokset 10 vuoden seurannan aikana. Tutkielman aineiston muodostivat 50-57 –vuotiaat vaihdevuosi-ikäiset naiset (n=47), jotka osallistuivat vuosina 1996-1997 Jyväskylän yliopistossa toteutettuun satunnaistettuun lume-kontrolloituun tutkimukseen. HRT:n ja PA:n yhteisvaikutuksen selvittämistä varten tutkittavat jaettiin neljään r…

Perimenopausal women show modulation of excitatory and inhibitory neuromuscular mechanisms.

2021

Background Menopausal transition exposes women to an early decline in muscle force and motor function. Changes in muscle quality and function, especially in lower limbs, are crucial, as they expose individuals to increased risk of falls. To elucidate some of the related neuromuscular mechanisms, we investigated cortical inhibition and peripheral muscle twitch force potentiation in women during the early and late stages of perimenopause. Methods Participants were 63 women aged 48–55 years categorized as early (EP, n = 25) or late (LP, n = 38) perimenopausal according to serum follicle-stimulating hormone (FSH) levels and menstrual diaries. EP women had an irregular menstrual cycle and FSH  2…