Search results for "validation study"

Prognostic impact of copeptin in pulmonary embolism: a multicentre validation study.

2018

To externally validate the prognostic impact of copeptin, either alone or integrated in risk stratification models, in pulmonary embolism (PE), we performed a post hoc analysis of 843 normotensive PE patients prospectively included in three European cohorts.Within the first 30 days, 21 patients (2.5%, 95% CI 1.5–3.8) had an adverse outcome and 12 (1.4%, 95% CI 0.7–2.5) died due to PE. Patients with copeptin ≥24 pmol·L−1 had a 6.3-fold increased risk for an adverse outcome (95% CI 2.6–15.5, p<0.001) and a 7.6-fold increased risk for PE-related death (95% CI 2.3–25.6, p=0.001). Risk classification according to the 2014 European Society of Cardiology (ESC) guideline algorithm identified 248…

Are analysts doing method validation in liquid chromatography?

2014

International audience; Method validation is being applied in the reported analytical methods for decades. Even before this protocol was defined, authors already somehow validated their methods without full awareness. They wished to assure the quality of their work. Validation is an applied approach to verify that a method is suitable and rugged enough to function as a quality control tool in different locations and times. The performance parameters and statistical protocols followed throughout a validation study vary with the source of guidelines. Before single laboratory validation, an analytical method should be fully developed and optimized. The purpose of the validation is to confirm p…

Revision of the Student Adaptation to College Questionnaire (SACQ) for Use with Italian Students

2022

Background: This multistudy report was aimed at examining the psychometric properties in the Italian context of the Student Adaptation College Questionnaire (SACQ) that represents the most important self-report measure for assessing how students adjust to university. Methods: Three studies were conducted in order to revise and improve the instrument for being more efficient in measuring adjustment to university. Results: The final result was the SACQ-SF consisting in 12 item assessing three dimensions: a) student’s perception of one’s study skills (Studying); b) student’s sense of satisfaction with courses and programs (Satisfaction with curriculum); c) student’s evaluation of the degree to…

Eine Validierungsstudie der deutschen Version des Hypersexual Behavior Inventory (HBI)

2013

Hypersexuelles Erleben und Verhalten umfasst gemas der aktuell diskutierten diagnostischen Kriterien wiederkehrende und intensive sexuelle Fantasien, sexuelles Verlangen oder sexuelle Verhaltensweisen, die zu klinisch relevantem personlichen Leidensdruck oder Funktionseinbusen im sozialen oder beruflichen Umfeld oder in anderen wichtigen Bereichen fuhren konnen. Das Hypersexual Behavior Inventory (HBI, Reid et al., 2011) dient der Erfassung hypersexuellen Erlebens und Verhaltens anhand von 3 Faktoren (Coping, Kontrolle und Konsequenzen). Die vorliegende Studie diente der Uberprufung der psychometrischen Eigenschaften der deutschen Version des HBI. Im Rahmen einer Online-Studie wurde die deu…

The Organizational Climate for Sustainable Commuting: An Italian Validation Study in the Academic Sector

2021

Promoting sustainable commuting represents a valuable contribution to tackle the climate crisis, and organizations could act as frontrunners in this regard. Accordingly, conceptualizing and measuring how organizational environments contribute to sustainable commuting has become relevant. This study aims to conceptualize and operationalize the construct of Organizational Climate for Sustainable Commuting (OCSC) and validate the OCSC scale in the Italian language. Data were gathered in an Italian university from 8542 participants. The validation was based on EFA and CFA, reliability, and aggregation indices analyses. To validate the scale, convergent, discriminant, internal construct, and cri…

What Does Spiritual Wellbeing Mean to You? Understandings of International Participants in the Validation Study for the EORTC QLQ-SWB32: An EORTC Mea…

2018

Validating a Test for Measuring Knowledge and Understanding of Economics Among University Students

2019

Abstract. University students' knowledge and understanding of economics have mostly been investigated cross-sectionally; however, longitudinal analyses are needed to determine which factors influence knowledge development and to draw valid conclusions based on test results. In the WiWiKom II project, a quasi-experimental longitudinal study was conducted assessing bachelor students of business and economics over the course of their studies in Germany (N = 39 universities). In this project, running from 2016 – 2019, the test-takers complete the WiWiKom II-test of economic knowledge (adapted TUCE4G and TEL4G items) and a general cognitive ability test (BEFKI 11) at four measurement points, ea…

Real-Time Photoplethysmography Imaging System

2011

Real-time non-contact photoplethysmography imaging (PPGI) system for high-resolution blood perfusion mapping in human skin has been proposed. The PPGI system comprises of LED lamp, webcam and computer with video processing software. The purpose of this study is to evaluate the reliability of the PPGI system when measuring blood perfusion. The validation study of PPGI and laser-Doppler perfusion imager (LDPI) was performed during local warming of palm skin. Results showed that the amplitude of PPGI increases immediately after warming and well correlated with the mean LDPI amplitude (R=0.92+-0.03, p<0.0001). We found that PPGI technique has good potential for non-contact monitoring of blood p…

Heart rate responses during the modified six-minute walk test among Special Olympics athletes

2021

Objective: The construct validity of the modified six-minute walk test (m6MWT) was examined by addressing the following questions: 1) do participants attain a steady state plateau in heart rate (HR) within the range of 110-150 beats per minute? 2) at what percentage of their predicted HR maximum were participants during each minute of the test? Material and Methods: Participants were 36 (male=56%) Special Olympics athletes aged 34.4 years (SD = 12.7). Following familiarization, participants completed the m6MWT while wearing a Polar Team 2 heart rate monitor. Results: By the end of the first minute, average heart rate was 120bpm, and a factorial repeated measures ANOVA revealed that steady s…

Draining and drying process development of the Tokamak Cooling Water System of ITER

2016

Abstract The ITER Organization (IO) developed a thermal-hydraulic (TH) model of the complex first wall and blanket (FW/BLK) cooling channels to determine gas flow rate and pressure required to effectively blow out the water in the FW/BLK. In addition, US ITER conducted experiments for selected geometries of FW/BLK flow channels to predict the blowout parameters. The analysis indicates that as low as 2 MPa of pressure difference over the blanket modules will ensure substantial evacuation of the water in blankets with just a few percent remaining in the blanket flow channels. A limited validation study indicates that the analysis yields less conservative results to compare against data collec…