Search results for "validation"

showing 10 items of 620 documents

Overview of Prognostic Systems for Hepatocellular Carcinoma and ITA.LI.CA External Validation of MESH and CNLC Classifications

2021

Simple Summary This review proposes a comprehensive overview of the main prognostic systems for HCC classified as prognostic scores, staging systems, or combined systems. Prognostic systems for HCC are usually compared in terms of homogeneity, monotonicity of gradients, and discrimination ability. However, despite the great number of published studies comparing HCC prognostic systems, it is rather difficult to identify a system that could be universally accepted as the best prognostic scheme for all HCC patients encountered in clinical practice. In order to give a contribute in this topic, we conducted a study aimed at externally validate the MESH score and the CNLC classification using the…

Cancer Researchmedicine.medical_specialtyReviewlcsh:RC254-282Prognostic score03 medical and health sciences0302 clinical medicinemedicineIn patientMedical physicsStaging systemmonotonicity of gradientsSettore MED/12 - Gastroenterologiadiscrimination ability; hepatocellular carcinoma; homogeneity; monotonicity of gradients; prognostic performance; prognostic systembusiness.industryprognostic systemExternal validationMono-tonicity of gradienthepatocellular carcinomamedicine.diseaselcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogensSettore MED/18homogeneityOncology030220 oncology & carcinogenesisHepatocellular carcinomaPopulation data030211 gastroenterology & hepatologyGeneral healthdiscrimination abilityLiver dysfunctionbusinessprognostic performanceCancers
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Canopy chlorophyll content and LAI estimation from Sentine1-2: Vegetation indices and Sentine1-2 Leve1-2A automatic products comparison

2019

The aim of this work is to analyze different methodologies for the estimation of leaf area index (LAI) and canopy chlorophyll content (CCC), using the Sentine1-2 satellite. LAI and CCC are biophysical parameters indicator of crop health state and fundamental in the productivity prediction. The purpose is to define the most optimal LAI and CCC estimation method for operational use in the monitoring of agricultural areas. Moreover, the CCC and LAI automatic products obtained directly through the Sentinel Application Platform Software (SNAP) biophysical processor and Sentine1-2 images by means of an artificial neural network (ANN) are validated. On the other hand, common vegetation indices use…

CanopyDiscrete mathematicsvalidationChlorophyll contentMean squared errorcanopy chlorophyll contentState (functional analysis)VegetationLAIvegetation indicesSaturation (graph theory)Leaf area indexSentinel-2Mathematics
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Relating Hyperspectral Airborne Data to Ground Measurements in a Complex and Discontinuous Canopy

2015

The work described in this paper is aimed at validating hyperspectral airborne reflectance data collected during the Regional Experiments For Land-atmosphere EXchanges (REFLEX) campaign. Ground reflectance data measured in a vineyard were compared with airborne reflectance data. A sampling strategy and subsequent ground data processing had to be devised so as to capture a representative spectral sample of this complex crop. A linear model between airborne and ground data was tried and statistically tested. Results reveal a sound correspondence between ground and airborne reflectance data (R2 > 0.97), validating the atmospheric correction of the latter.

CanopyvalidationData processing010504 meteorology & atmospheric sciencesMeteorologyhyperspectral remote sensingAtmospheric correctionAHSreflectance field spectrometryHyperspectral imagingSampling (statistics)15. Life on land010502 geochemistry & geophysics01 natural sciencesReflectivityGeophysicsEnvironmental science0105 earth and related environmental sciencesRemote sensingActa Geophysica
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An Overview of the Regional Experiments for Land-Atmosphere Exchanges 2012 (Reflex 2012) Campaign

2015

The REFLEX 2012 campaign was initiated as part of a training course on the organization of an airborne campaign to support advancement of the understanding of land-atmosphere interaction processes. This article describes the campaign, its objectives and observations, remote as well as in situ. The observations took place at the experimental Las Tiesas farm in an agricultural area in the south of Spain. During the period of ten days, measurements were made to capture the main processes controlling the local and regional land-atmosphere exchanges. Apart from multi-temporal, multi-directional and multi-spatial space-borne and airborne observations, measurements of the local meteorology, energy…

CarbonioCalibration and validation010504 meteorology & atmospheric sciencesMeteorologyTraining courseland-atmosphere interaction010502 geochemistry & geophysics01 natural sciences7. Clean energyLand-atmosphere interactionAtmosphereSoil temperatureSettore BIO/07 - ECOLOGIACalibration and validationCarbon fluxes0105 earth and related environmental sciencescalibration and validationMulti-scale heterogeneityquantitative remote sensingturbulenceTelerilevamentoTurbulenceAtmosferaGeophysicsmulti-scale heterogeneityEnvironmental scienceddc:526Quantitative remote sensingActa Geophysica
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In silico prediction of central nervous system activity of compounds. Identification of potential pharmacophores by the TOPS–MODE approach

2004

The central nervous system (CNS) activity has been investigated by using a topological substructural molecular approach (TOPS-MODE). A discriminant analysis to classify CNS and non-CNS drugs was developed on a data set (302 compounds) of great structural variability where more than 81% (247/302) were well classified. Randic's orthogonalization procedures was carried out to allow the interpretation of the model and to avoid the collinearity among descriptors. The discriminant model was assessed by a leave-n-out (when n varies from 2 to 20) cross-validation procedure (79.94% of correct classification), an external prediction set composed by 78 CNS/non-CNS drugs (80.77% of correct classificati…

Central Nervous SystemMolecular modelChemistryStereochemistryIn silicoOrganic ChemistryClinical BiochemistryPharmaceutical ScienceCollinearityComputational biologyLinear discriminant analysisModels BiologicalBiochemistryCross-validationPolar surface areaStructure-Activity RelationshipPredictive Value of TestsDrug DiscoveryMolecular MedicinePharmacophoreMolecular BiologyOrthogonalizationCentral Nervous System AgentsBioorganic & Medicinal Chemistry
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Safety culture assessment in high reliability organizations: the use of questionnaires in the nuclear industry

2017

El objetivo principal de esta tesis es proporcionar una visión general de las formas actuales de entender, tratar, y evaluar la cultura de la seguridad (poniendo un énfasis particular en la industria nuclear y en la utilización de cuestionarios), y proporcionar orientación a los investigadores y profesionales sobre cómo capturar la cultura de seguridad de las centrales nucleares. Para ello, la tesis actual incluye los siguientes capítulos: CAPÍTULO I - Se presenta una breve introducción a la industria nuclear. Asimismo se presentan algunos de los más destacables pros y contras de la energía nuclear, y desafíos importantes a los que la industria nuclear se estado enfrentando en los últimos a…

Central nuclearValidación de cuestionariosOrganizational cultureUNESCO::PSICOLOGÍA::Psicología industrialNuclear industryNuclear power plantIndustria nuclearValidation of questionnairesSafety performance:PSICOLOGÍA::Psicología industrial [UNESCO]Safety cultureCultura de seguridadCultura organizacionalDesempeño de seguridad
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343 External validation of tumour-free distance as novel prognostic marker in early-stage cervical cancer undergoing primary surgery

2020

Introduction Tumor-free distance (TFD), defined as the minimum distance of uninvolved stroma between the tumor and peri-cervical stromal ring, was recently proposed as predictive marker of recurrence in patients with early-stage cervical cancer treated by primary surgery (particularly if ≤3.5 mm). The aims of the present study were to assess the prognostic value of TFD and to compare TFD with other known prognostic markers in early-stage cervical cancer. Methods Patients with pathologic FIGO 2009 stage IA1-IIB cervical cancer, treated by primary radical surgical treatment between 01/2000 and 12/2018, were retrospectively included. Adjuvant treatment was administered according to the presenc…

Cervical cancermedicine.medical_specialtyMultivariate analysisPredictive markerHysterectomyParametrialbusiness.industrymedicine.medical_treatmentExternal validationmedicine.diseaseSurgeryLaparotomymedicineStage (cooking)businessPoster
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Regional and experiential differences in surgeon preference for the treatment of cervical facet injuries: a case study survey with the AO Spine Cervi…

2021

Abstract Purpose The management of cervical facet dislocation injuries remains controversial. The main purpose of this investigation was to identify whether a surgeon’s geographic location or years in practice influences their preferred management of traumatic cervical facet dislocation injuries. Methods A survey was sent to 272 AO Spine members across all geographic regions and with a variety of practice experience. The survey included clinical case scenarios of cervical facet dislocation injuries and asked responders to select preferences among various diagnostic and management options. Results A total of 189 complete responses were received. Over 50% of responding surgeons in each region…

Cervical spine; Joint dislocations; Neck injuries; Spinal diseases; Spinal injuries; Traumamedicine.medical_specialtyFacet (geometry)Neck injurieNeuroscience(all)610 Medicine & healthExperiential learningTraumaJoint dislocation03 medical and health sciencesJoint dislocations0302 clinical medicineCervical spineSpinal diseasemedicineHumansOrthopedics and Sports Medicine030212 general & internal medicineJoint dislocation610 Medicine & healthCervical spine ; Joint dislocations ; Neck injuries ; Spinal diseases ; Spinal injuries ; TraumaSurgeonsValidation groupSpinal injuriebusiness.industrySpine.cervicalmedicine.diseasePreferenceNeck injuriesSpinal injuriesSpinal FusionCervical VertebraePhysical therapySurgeryNeurosurgeryAnterior approachbusiness030217 neurology & neurosurgerySpinal diseases
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The Italian validation of the Montreal Global definition and classification of gastroesophageal reflux disease

2009

Recently, a Global definition and a classification of gastroesophageal reflux disease (GERD) were developed by Montreal Consensus Group, composed of international expert gastroenterologists. Guidelines and consensus documents are, however, infrequently accepted and adopted at a local level. The aim of this study was to measure the acceptance of Montreal Global definition of GERD consensus document by specialists in a single country (Italy) and to measure the linguistic, scientific, and practical differences between the international consensus document and the Italian version.A 2-day meeting was held in June 2007 in Rome, Italy, attended by 147 Italian physicians who were experts in gastroen…

Chest Painmedicine.medical_specialtyValidation studyEsophageal NeoplasmseducationMEDLINEDiseaseAdenocarcinomaGastroenterologyBarrett EsophagusTerminology as TopicInternal medicineHumansMedicineLanguageEvidence-Based MedicineHepatologybusiness.industryGastroenterologyRefluxSyndromeEvidence-based medicinemedicine.diseasedigestive system diseasesItalyEsophageal stenosisFamily medicinePractice Guidelines as TopicEsophageal StenosisGastroesophageal RefluxGERDbusinessPremalignant lesionEuropean Journal of Gastroenterology & Hepatology
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Determination of cholesterol in human milk: an alternative to chromatographic methods

2015

Introduction: human milk (HM) is considered the best option for feeding healthy infants. Cholesterol (CHOL) is important for proper development of the nervous system, and for hormone and vitamin synthesis in growing infants. Breastfeeding and dietary CHOL intake during infancy have been suggested to affect blood lipid levels and the risk of cardiovascular disease in adulthood. Gas chromatography is the technique most widely used to determine CHOL in HM. Chromatographic methods are specific for the determination of CHOL and other sterols present in HM, but are extremely time consuming, and the costs and equipment requirements mean that they are not accessible to all laboratories. Aim: the pr…

Cholesterol determinationHuman milkValidationtechnology industry and agriculturepolycyclic compoundslipids (amino acids peptides and proteins)Enzymatic-spectrophotometric method
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