Search results for "validation"

showing 10 items of 620 documents

Optimizing the clinical utility of PCA3 to diagnose prostate cancer in initial prostate biopsy.

2015

Background: PCA3 has been included in a nomogram outperforming previous clinical models for the prediction of any prostate cancer (PCa) and high grade PCa (HGPCa) at the initial prostate biopsy (IBx). Our objective is to validate such IBx-specific PCA3-based nomogram. We also aim to optimize the use of this nomogram in clinical practice through the definition of risk groups. Methods: Independent external validation. Clinical and biopsy data from a contemporary cohort of 401 men with the same inclusion criteria to those used to build up the reference’s nomogram in IBx. The predictive value of the nomogram was assessed by means of calibration curves and discrimination ability through the area…

PCA3MaleCancer Researchmedicine.medical_specialtyProstate biopsyBiopsyUrologyurologic and male genital diseasesRisk AssessmentDecision Support TechniquesCohort StudiesProstate cancerRisk groupsAntigens NeoplasmRisk FactorsGeneticsBiomarkers TumorMedicineHumansOpportunistic screeningAgedmedicine.diagnostic_testbusiness.industryArea under the curveExternal validationProstatic NeoplasmsOrgan SizeNomogramMiddle Agedmedicine.diseaseSurgeryNomogramsOncologybusinessBiomarkersResearch ArticleBMC cancer
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Measurement invariance of the Prosocial Behavior Scale in three hispanic countries (Argentina, Spain, and Peru)

2020

Fil: Martí-Vilar, Manuel. Universitat de Valéncia. Facultat de Psicología. Departament de Psicología Básica; España Fil: Merino-Soto, César. Universidad de San Martín de Porres. Instituto de Investigación de Psicología; Perú Fil: Rodríguez, Lucas Marcelo. Pontificia Universidad Católica Argentina. Facultad Teresa de Ávila. Centro de Investigación Interdisciplinar en Valores, Integración y Desarrollo Social; Argentina Abstract: In a growing context of multiculturalism, prosocial behavior is important to build effective social exchange and service orientation among university students. The present study investigates prosocial behavior from a psychometric approach, to obtain evidence of the in…

PSICOMETRIAassessmentlcsh:BF1-990EspañaArgentinaContext (language use)Structural equation modelingsocial behaviorlaw.inventionlawPeruPsychologyMeasurement invarianceuniversity studentsGeneral PsychologyOriginal ResearchvalidationinterculturalESTUDIANTES UNIVERSITARIOSINTERCULTURALIDADmeasurement invarianceCONDUCTA PROSOCIALlcsh:PsychologyProsocial behaviorprosocialSocial exchange theoryTest scoreScale (social sciences)CLARITYPsychologySocial psychology
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Women's satisfaction with the experience of childbirth: validation of the Mackey Childbirth Satisfaction Rating Scale

2012

Objetivos: Determinar la fiabilidad y validez de contenido y concepto de la Mackey Childbirth Satisfaction Rating Scale, escala para medir la satisfacción de las mujeres con el parto y el nacimiento. Métodos: Se utilizó el método de traducción-retrotraducción para obtener una versión adaptada de la escala. Para la validación se seleccionó una muestra de 325 mujeres que habían tenido un hijo sano mediante parto vaginal. La recogida de datos se realizó con un cuestionario autocumplimentado que incluía la escala adaptada, expectativas ante el parto y variables obstétricas y sociodemográficas. Se valoró la fiabilidad en una submuestra de 45 mujeres que cumplimentaron de nuevo la escala a los 15…

PartoEstudios de validaciónValidation studiesEscalasScalesPatient satisfactionSatisfacción del pacienteDelivery
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Satisfacción de las mujeres con la experiencia del parto: validación de la Mackey Satisfaction Childbirth Rating Scale Women's satisfaction with the …

2012

Objetivos: Determinar la fiabilidad y validez de contenido y concepto de la Mackey Childbirth Satisfaction Rating Scale, escala para medir la satisfacción de las mujeres con el parto y el nacimiento. Métodos: Se utilizó el método de traducción-retrotraducción para obtener una versión adaptada de la escala. Para la validación se seleccionó una muestra de 325 mujeres que habían tenido un hijo sano mediante parto vaginal. La recogida de datos se realizó con un cuestionario autocumplimentado que incluía la escala adaptada, expectativas ante el parto y variables obstétricas y sociodemográficas. Se valoró la fiabilidad en una submuestra de 45 mujeres que cumplimentaron de nuevo la escala a los 15…

PartoEstudios de validaciónValidation studieslcsh:Public aspects of medicineEscalasScalesPatient satisfactionlcsh:RA1-1270Satisfacción del pacienteDeliveryGaceta Sanitaria
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Validation and reproducibility of dietary assessment methods in adolescents: a systematic literature review.

2013

AbstractObjectiveThe aim of the present work was to determine what dietary assessment method can provide a valid and accurate estimate of nutrient intake by comparison with the gold standard.DesignA MEDLINE, EMBASE, ISI Web of Science, Cochrane and related references literature review was conducted on dietary assessment methods for adolescents reporting the validity and/or reproducibility values. A study quality assessment on the retrieved FFQ was carried out according to two different scoring systems, judging respectively the quality of FFQ nutrition information and of FFQ validation and calibration.SettingThe present review considered adolescents attending high schools and recruited in ho…

Pathologymedicine.medical_specialtyDietary assessmentAdolescentMEDLINEReproducibility of ResultMedicine (miscellaneous)Settore MED/42 - Igiene Generale E ApplicataDiet SurveysFood groupAdolescents; Dietary assessment; Reproducibility; Validation; Adolescent; Humans; Reproducibility of Results; Diet; Diet Surveys; Food Habits; Nutrition Assessment; Surveys and Questionnaires; Medicine (miscellaneous); Nutrition and Dietetics; Public Health Environmental and Occupational Health; Medicine (all)Environmental healthSurveys and QuestionnairesValidationNutrition and DieteticMedicineSurveys and QuestionnaireHumansNutrition informationReproducibilityNutrition and Dieteticsbusiness.industryMedicine (all)Public Health Environmental and Occupational HealthReproducibility of ResultsGold standard (test)Feeding BehaviorDiet SurveysReproducibilityDietDiet SurveySystematic reviewNutrition AssessmentDietary assessmentFood HabitbusinessHumanPublic health nutrition
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Validity of needle core biopsy in the histological characterisation of mammary lesions

2006

Summary Over the last few years, there has been an enormous increase in the use of needle core biopsy (CB) for the histopathological characterisation of suspect lesions of the breast. The aim of this study was to verify the diagnostic reliability of CB by comparing the histological results obtained with the use of this technique with those obtained from the whole of the surgically resected specimen. We studied 198 out of 426 patients with clinically and/or radiologically suspect breast lesions. We found correspondence between the histological examination of the whole of the excised specimen and that of the CB in 94.9% of the cases of infiltrating carcinoma and in 71.4% of those involving du…

Pathologymedicine.medical_specialtyReproducibility of ResultBreast NeoplasmsSensitivity and SpecificityBreast cancerNeedle core biopsyRetrospective StudiemedicineCarcinomaHumansbreast carcinomahumanintermethod comparisonarticle; breast carcinoma; breast disease; carcinoma in situ; diagnostic accuracy; diagnostic value; histopathology; human; human tissue; intermethod comparison; intraductal carcinoma; major clinical study; needle biopsy; prediction; priority journal; reliability; sensitivity and specificity; validation process Biopsy Needle; Breast Neoplasms; Carcinoma Ductal Breast; Carcinoma Intraductal Noninfiltrating; Female; Humans; Reproducibility of Results; Retrospective Studies; Sensitivity and Specificity [EMTREE medical terms]Retrospective Studiesintraductal carcinomaHistological examinationreliabilitybusiness.industryBiopsy Needlevalidation process MeSH: Biopsy NeedleCarcinoma Ductal Breastbreast diseaseReproducibility of Resultscarcinoma in situneedle biopsypredictionGeneral Medicinemedicine.diseasemajor clinical studyPredictive valuehuman tissueCarcinoma Intraductal Noninfiltratingpriority journalhistopathologyEMTREE medical terms: articlediagnostic accuracyFemaleSurgerydiagnostic valueRadiologybusinessCore biopsyBreast NeoplasmThe Breast
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VALIDACIÓN DE UNA ESCALA PARA EL ANÁLISIS DE LAS PERCEPCIONES DE LOS RESIDENTES SOBRE EL IMPACTO SOCIAL DE UN CENTRO DEPORTIVO

2019

Resumen La finalidad de este estudio es validar una escala para el análisis de las percepciones de los residentes sobre el impacto social de un centro deportivo. Se recogió una muestra de 406 residentes del municipio de Moncada (Valencia), con un error de muestreo de ±4,82, que contestaron a una encuesta de 31 ítems que recogían posibles impactos sociales derivados de la presencia del centro deportivo en la localidad. La aplicación de análisis factorial exploratorio y confirmatorio redujo la escala a 28 indicadores distribuidos en siete dimensiones de impacto: impacto sociocultural, impacto socioeconómico, impacto en la imagen y la promoción del municipio, impacto en el desarrollo urbano y …

Percepção socialAcademias de ginásticaSocial perceptionWelfare economicsSocial changeSocial impactPhysical activityValiditySampling errorFitness centresConfirmatory factor analysisEducationEstudios de validaciónCambio socialValidation studiesUrban planningCentros de acondicionamientoMudança socialEstudos de validaçãoScale (social sciences)SociologyPercepción socialMovimento (ESEFID/UFRGS)
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PMT: New analytical framework for automated evaluation of geo-environmental modelling approaches

2019

Geospatial computation, data transformation to a relevant statistical software, and step-wise quantitative performance assessment can be cumbersome, especially when considering that the entire modelling procedure is repeatedly interrupted by several input/output steps, and the self-consistency and self-adaptive response to the modelled data and the features therein are lost while handling the data from different kinds of working environments. To date, an automated and a comprehensive validation system, which includes both the cutoff-dependent and –independent evaluation criteria for spatial modelling approaches, has not yet been developed for GIS based methodologies. This study, for the fir…

Performance analysiEnvironmental EngineeringGeospatial analysis010504 meteorology & atmospheric sciencesComputer scienceSettore GEO/04 - Geografia Fisica E GeomorfologiaComputationGoodness-of-fit010501 environmental sciencescomputer.software_genre01 natural sciencesRobustness (computer science)ValidationEnvironmental ChemistryWaste Management and Disposal0105 earth and related environmental sciencescomputer.programming_languageEnvironmental modellingReceiver operating characteristicSpatial modellingPerformance analysisLandslidePMTPython (programming language)22/4 OA procedurePollutionDrought riskITC-ISI-JOURNAL-ARTICLEData miningPredictive model evaluation frameworkcomputerScience of The Total Environment
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Machine-learned selection of psychological questionnaire items relevant to the development of persistent pain after breast cancer surgery

2018

Background: Prevention of persistent pain after breast cancer surgery, via early identification of patients at high risk, is a clinical need. Psychological factors are among the most consistently proposed predictive parameters for the development of persistent pain. However, repeated use of long psychological questionnaires in this context may be exhaustive for a patient and inconvenient in everyday clinical practice. Methods: Supervised machine learning was used to create a short form of questionnaires that would provide the same predictive performance of pain persistence as the full questionnaires in a cohort of 1000 women followed up for 3 yr after breast cancer surgery. Machine-learned …

Persistence (psychology)PREDICTIONINVENTORYAngerpatientsCohort StudiesMachine LearningFEAR-AVOIDANCE MODEL0302 clinical medicine030202 anesthesiologySurveys and Questionnairespsychological questionnairesANXIETYProspective cohort studyMastectomySCALEDepression (differential diagnoses)Pain MeasurementPain PostoperativeDepressionmachine-learningFear-avoidance modelMiddle AgedCohortAnxietyFemaleChronic PainSENSITIVITYmedicine.symptomAdultmedicine.medical_specialtyBreast NeoplasmsContext (language use)behavioral disciplines and activitiesVALIDATIONCHRONIC MUSCULOSKELETAL PAIN03 medical and health sciencesbreast cancerBreast cancerPredictive Value of TestsmedicineHumanspersisting painddc:610Psychiatric Status Rating ScalesACUTE POSTOPERATIVE PAINbusiness.industry3126 Surgery anesthesiology intensive care radiologymedicine.diseaseSurgeryAnesthesiology and Pain MedicinePROSPECTIVE COHORTdata sciencebusiness030217 neurology & neurosurgeryBritish Journal of Anaesthesia
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A topological sub-structural approach for predicting human intestinal absorption of drugs.

2004

The human intestinal absorption (HIA) of drugs was studied using a topological sub-structural approach (TOPS-MODE). The drugs were divided into three classes according to reported cutoff values for HIA. "Poor" absorption was defined as HIAor =30%, "high" absorption as HIAor =80%, whereas "moderate" absorption was defined between these two values (30%HIA79%). Two linear discriminant analyses were carried out on a training set of 82 compounds. The percentages of correct classification, for both models, were 89.02%. The predictive power of the models were validated by three test: a leave-one-out cross validation procedure (88.9% and 87.9%), an external prediction set of 127 drugs (92.9% and 80…

PharmacologyQuantitative structure–activity relationshipChemistryOrganic ChemistryBiological AvailabilityQuantitative Structure-Activity RelationshipGeneral MedicineModels TheoreticalLinear discriminant analysisTopologyCross-validationIntestinal absorptionBioavailabilityIntestinal AbsorptionPharmaceutical PreparationsTest setDrug DiscoveryHuman intestinal absorptionCutoffHumansIntestinal MucosaEuropean journal of medicinal chemistry
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