Search results for "validity"

showing 10 items of 891 documents

Evaluation of enantioselective binding of fluoxetine to human serum albumin by ultrafiltration and CE - Experimental design and quality considerations

2012

Several pharmacokinetic processes are affected by enantioselectivity (ES). At the level of distribution, protein binding (PB) is one of the most important. The enantioselective binding of fluoxetine (FLX) to HSA has been evaluated in this work by ultrafiltration of FLX–HSA mixtures and chiral analysis of unbound fractions by EKC-CD. PB, affinity constants (K) and ES were obtained for both enantiomers of FLX. In order to improve the consistency of the estimations, the evaluation of affinity constants of each enantiomer was performed using two designs, one keeping constant the total concentration of protein and varying the total concentration of the enantiomers, and the other in the opposite …

Clinical BiochemistrySerum albuminUltrafiltrationUltrafiltrationStereoisomerismBiochemistryAnalytical ChemistryFluoxetinemedicineHumansBinding siteSerum AlbuminChromatographybiologyChemistryEnantioselective synthesisElectrophoresis CapillaryReproducibility of ResultsStereoisomerismHuman serum albuminModel validityNonlinear Dynamicsbiology.proteinEnantiomerAlgorithmsProtein Bindingmedicine.drugELECTROPHORESIS
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Setbacks in Self-Control: Failing Not Mere Resisting Impairs Subsequent Self-Control

2020

Research on ego depletion has often relied on the dual-task setting employing short tasks with low ecological validity. The comparatively few studies on ego depletion in daily life so far used diverging operationalization and yielded ambiguous results. We argue that fundamental research on short-term self-control limitations can benefit from research on the limit violation effect, which highlights the danger to self-control when setbacks are attributed to internal causes. To test the role of setbacks and compare different ego depletion operationalizations in daily life, we used data from two ambulatory assessment studies ( N = 125 and 205). No consistent ego depletion effects were observed…

Clinical PsychologyEgo depletionSocial PsychologyEcological validitymedia_common.quotation_subject05 social sciences050109 social psychology0501 psychology and cognitive sciencesSelf-controlPsychologySocial psychology050105 experimental psychologymedia_commonSocial Psychological and Personality Science
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Measuring Internet Gaming Disorder and Gaming Disorder: A Qualitative Content Validity Analysis of Validated Scales

2021

Numerous instruments have been developed to measure gaming-related health problems based on “internet gaming disorder” (IGD) in the third section of the Diagnostic and Statistical Manual of Mental Disorders (5th ed.) and “gaming disorder” (GD) in the International Classification of Diseases (11th rev.). However, the criteria in the manuals tend to be operationalized in numerous diverse ways, which can make screening outcomes incomparable. A content validity analysis is needed to reassess the relationships between the diagnostic criteria and the items that operationalize them. The IGD and GD criteria were divided into sematic components. A qualitative content validity analysis was carried o…

Clinical PsychologyHealth problemsbusiness.industryApplied psychologyContent validityThe InternetbusinessPsychologyApplied PsychologyAssessment
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Self-worth contingencies and obsessionality: A promising approach to vulnerability?

2012

Abstract Cognitive behavioral theories (CBT) posit deficiencies in selfhood processes as possible vulnerability factors for obsessive–compulsive disorder (OCD). This paper presents two psychometric studies on the development of the Obsessional Concerns and Self Questionnaire (OCSQ), a measure of failure to attain self-worth in personal domains relevant to obsessionality. In the first study based on 563 community Spaniards, principal factor analysis of an 80 item pool resulted in a three factor solution and a final 35 item version (OCSQ-r). In the second study self-worth and symptom measures were administered to 152 Spanish, 142 Argentinean and 112 Canadian nonclinical samples. Group compari…

Cognitive vulnerabilitymedia_common.quotation_subjectMultilevel modelVulnerabilityCognitionbehavioral disciplines and activitiesDevelopmental psychologyPsychiatry and Mental healthClinical PsychologyConvergent validityPersonalitySelf worthWorryPsychologymedia_commonClinical psychologyJournal of Obsessive-Compulsive and Related Disorders
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All Student Samples Differ: On Participant Selection in Communication Science

2012

When conducting experiments, researchers in communication science often rely on convenience samples of students. This study provides evidence consistent with a concern that between-participant differences in exposure to communication theories can be a threat to the internal validity of conclusions reached. Using cultivation theory as a context for studying this threat, this study examines the influence of stage in university education and discipline of study on the ability to detect the cultivation hypothesis and participants' responses to questions regularly used in studies of cultivation. We found that university students at different stages of their studies and studying different discipl…

CommunicationSelection (linguistics)Cultivation theoryUniversity educationContext (language use)Internal validityPsychologySocial psychologyCommunication theoryCommunication Methods and Measures
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The Transcultural Community Resilience Scale: Psychometric Properties and Multinational Validity in the Context of the COVID-19 Pandemic

2021

Few instruments assess community resilience. In the midst of the COVID-19 pandemic, the capacity of communities to support resilience of members deserves to be assessed to develop programs for improving mental health of affected populations. This article presents the development of the Transcultural-Community Resilience Scale (T-CRS), its underlying factorial structure and transcultural validity with a multilingual (English, French, Creole, Kinyarwanda), multinational (DR Congo, Haiti, Rwanda, Togo) and multicultural sample affected by this pandemic. A sample of 1,267 participants (40.9% women) were recruited in the four countries: DRC (n = 626, 43.4% women), Haiti (n = 225, 42.0% women), R…

Community resiliencemedia_common.quotation_subjectConcurrent validityCorrectionConstruct validityContext (language use)Brief Research ReportMental healthConfirmatory factor analysisBF1-990multinational sampleCronbach's alphadepressionmultinational validationPsychologyPsychological resiliencemultilingual samplePsychologyTranscultural Community Resilience Scale psychometric propertiesGeneral PsychologyClinical psychologymedia_commonFrontiers in Psychology
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Methodological considerations for interrupted time series analysis in radiation epidemiology: an overview

2021

Interrupted time series analysis (ITSA) is a method that can be applied to evaluate health outcomes in populations exposed to ionizing radiation following major radiological events. Using aggregated time series data, ITSA evaluates whether the time trend of a health indicator shows a change associated with the radiological event. That is, ITSA checks whether there is a statistically significant discrepancy between the projection of a pre-event trend and the data empirically observed after the event. Conducting ITSA requires one to consider specific methodological issues due to unique threats to internal validity that make ITSA prone to bias. We here discuss the strengths and limitations of …

Computer scienceConfoundingPublic Health Environmental and Occupational HealthInterrupted Time Series AnalysisStatistical modelGeneral MedicineHealth indicatorInterrupted Time Series AnalysisResearch DesignData qualityEconometricsInternal validityTime seriesSpurious relationshipWaste Management and DisposalForecastingJournal of Radiological Protection
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Propiedades psicométricas del Cuestionario de conciencia emocional en población infantil española

2016

La competencia emocional es la capacidad para percibir, expresar, comprender, regular y controlar nuestras emociones y las de los demás. La conciencia emocional es la competencia básica que permite el desarrollo del resto de competencias emocionales durante la infancia y la adolescencia. En este trabajo, se han estudiado las propiedades psicométricas de la versión española del Cuestionario de conciencia emocional, administrado a 1476 niños/as españoles (8-12 años). Se ha replicado la estructura original formada por seis factores. Se han estudiado la fiabilidad de los ítems y del instrumento, la validez de constructo, de contenido y concurrente, los resultados han sido satisfactorios. Se han…

Concepto moralConcurrent validityEmotions050109 social psychologyCuestionario de conciencia emocionalEmotional competenceDevelopmental psychologyAge and genderEmotional competencesCompetencias emocionalesContent validity0501 psychology and cognitive sciencesEvaluationCompetence (human resources)Psychology(all)NiñosGeneral PsychologyCompetencias emocionales; Conciencia emocional; Evaluación; Infancia; Autoinforme; Cuestionario de conciencia emocionalEmotional Awareness QuestionnaireEvaluación05 social sciencesConstruct validitySpanish versionEmotional awarenessConciencia emocionalPsicología - MetodologíaChildhoodEmocionesAutoinformeEmotion awarenessPsicometríaChilhoodInfanciaPsychologySelf-reportSocial Sciences (miscellaneous)050104 developmental & child psychology
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Desarrollo y evaluación psicométrica de una forma abreviada de la escala de posicionamiento ante el diagnóstico enfermero

2013

El Position on Nursing Diagnosis (PND) es una escala que utiliza la técnica del diferencial semántico para medir las actitudes hacia el concepto diagnóstico enfermero. El estudio objetivó desarrollar una forma abreviada de la versión española de esta escala, evaluar sus propiedades psicométricas y eficiencia. Se utilizó un doble enfoque empírico-teórico para obtener una forma reducida del PND, el PND-7-SV, que fuera equivalente a la original. Mediante un diseño transversal a través de encuesta, se evaluó la fiabilidad (consistencia interna y fiabilidad test-retest), validez de constructo (análisis factorial exploratorio, técnica de grupos conocidos y validez discriminante) y de criterio (va…

Concurrent validityDiferencial semánticoEscales (Ciències socials)NursingDiagnòsticInfermeriamental disordersEstudiantes de enfermeríaDiagnóstico de enfermeríaDiferencial semanticoEstudiantes de enfermeriaGeneral NursingReliability (statistics)lcsh:RT1-120lcsh:NursingDiscriminant validitySurvey researchExploratory factor analysisScale (social sciences)Diagnostico de enfermeriaEscalasPsicometríaSemantic differentialPsychologyPsicometriaNursing diagnosis
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Evidence of validity and measurement invariance by gender of the Vaccination Attitudes Examination (VAX) scale in Colombian university students

2022

Background: Having a valid tool to assess attitudes toward vaccination and identify the concerns that drive vaccine refusal can facilitate population studies and help guide public health interventions. The objective of this study has been to adapt the Vaccination Attitudes Examination (VAX) scale in Colombian university students and to study its psychometric properties in a non-probabilistic sample of 1074 Colombian university students. Methods: A confirmatory factor analysis was used to study the factorial structure. A structural equation model was tested to study concurrent validity and to check whether the factors predicted having received the coronavirus vaccine. Gender-based measuremen…

Conducta (Psicologia)General MedicineComportament col·lectiuvaccine hesitancy; vaccine refusal; confirmatory factor analysis; structural equation modeling; measurement invariance; concurrent validity; psychometric properties; COVID-19
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