Search results for "variant"

Torre del Greco, villa marittima in contrada Sora: 65. Statua di Satiro

2019

Si presenta il più noto reperto scultoreso dalla Villa di Contrada Sora a Torre del Greco, sondata per cunicoli dall'allora principe ereditario della dinastia borbonica, al cui seguito il reperto giunse a Palermo all'epoca della fuga della famiglia reale per l'avanzata francese. Il Satiro, una delle migliori repliche del celeberrimo Satiro Versante di Prassitele, consente di individuare alcune specificità della rielaborazione copistica rispondenti al gusto del facoltoso committente della costa vesuviana.

Introduzione a Silvana Grasso, Enrichetta

2016

Anamnesi di un’analoga ossessione è questo volume. Quattro Enrichette, specchio biografico di un’identità impossibile da definire, si susseguono nella scrittura di Silvana Grasso, portando alla riemersione le «cellule staminali» di un mito metamorfico che condanna il personaggio da un lato all’eccezionalità e dall’altro alla solitudine. Quattro forme testuali per riaccendere un ricordo aurorale: un essere anfibio, di confine, metamorfico per natura e/o per scelta, che vive l’essere per sé sul crinale dell’essere per gli altri, che rappresenta, senza sottoporre ad alcun giudizio morale, ciò che l’umanità ‘normale’ rifugge e contemporaneamente cerca.

The Reciprocal Influences among Motivation, Personality Traits, and Game Habits for Playing Pokémon GO

2018

This article reports a study exploring motivations of Pokémon Game use, individual differences related to personality traits, and game habits. First, it analyzed Pokémon GO motivations through exploratory factor analysis (EFA) by administering online the Pokémon GO Motivational Scale to a group of Italian gamers (N = 560). Successively, a Confirmatory Factor Analysis (CFA) was conducted testing three factorial models of Pokémon Game motivations on a selected random sample (N = 310). Results showed a three-factor model of Pokémon GO Game motivations (i.e. Personal Needs, Social Needs and Recreation), accounting for 68.9% of total variance plus a general higher order factor that best fits the…

ALGEBRE SIMMETRICHE DI ALCUNE CLASSI DI IDEALI MONOMIALI

The purpose of this thesis is the study of the symmetric algebra 〖Sym〗_S (L) of an interesting class of monomial ideals: the ideals L ⊂S=K[x1,...,xn,y1,...,ym] of mixed products in two sets of variables. Recently, this class is been used in order to test some algebraic conjecture, including the conjecture of Eisenbud -Goto, on the symmetric algebra 〖Sym〗_S (L) .Since such conjecture involves fundamental invariants of Sym (L), such as the Krull dimension, the multiplicity and regularity of Castelnuovo-Mumford, it was necessary to calculate these invariants or their bounds. This problem is difficult, but if L is generated by a s-sequence, you can arrive at a concrete result. In the work Mixed…

On invariant manifolds of saddle points for 3D multistable models

2017

In dynamical systems a particular solution is completely determined by the parameters considered and the initial conditions. Indeed, when the model shows a multistability, starting from different initial state, the trajectories can evolve towards different attractors. The invariant manifolds of the saddle points separate the vector field into the basins of attraction of different stable equilibria. The aim of this work is the reconstruction of these separation surfaces in order to know in advance the geometry of the basins. In this paper three-dimensional models with three or more stable fixed points is investigated. To this purpose a procedure for the detection of the scattered data lying …

Applicazioni potenziali dell’analisi di varianti geniche nella valutazione del rischio di Malattia Renale Cronica

2021

Analysis of early strains of the norovirus pandemic variant GII.4 Sydney 2012 identifies mutations in adaptive sites of the capsid protein.

2014

AbstractGlobal surveillance for norovirus identified in 2012 the emergence of a novel pandemic GII.4 variant, termed Sydney 2012. In Italy, the novel pandemic variant was identified as early as November 2011 but became predominant only in the winter season 2012–2013. Upon sequencing and comparison with strains of global origin, the early Sydney 2012 strains were found to differ from those spreading in 2012–2013 in the capsid (ORF2) putative epitopes B, C and D, segregating into a distinct phylogenetic clade. At least three residues (333, 340 and 393, in epitopes B, C and D, respectively) of the VP1 varied among Sydney 2012 strains of different clades. These findings suggest that the spread …

Epidemiological dynamics of norovirus GII.4 variant New Orleans 2009.

2015

Norovirus (NoV) is one of the major causes of diarrhoeal disease with epidemic, outbreak and sporadic patterns in humans of all ages worldwide. NoVs of genotype GII.4 cause nearly 80–90 % of all NoV infections in humans. Periodically, some GII.4 strains become predominant, generating major pandemic variants. Retrospective analysis of the GII.4 NoV strains detected in Italy between 2007 and 2013 indicated that the pandemic variant New Orleans 2009 emerged in Italy in the late 2009, became predominant in 2010–2011 and continued to circulate in a sporadic fashion until April 2013. Upon phylogenetic analysis based on the small diagnostic regions A and C, the late New Orleans 2009 NoVs circulati…

Sorveglianza delle gastroenteriti da Norovirus in Italia: comparsa e diffusione della nuova variante GII.4 Sydney 2012

2013

In the 2012-2013 winter season, global surveillance for norovirus circulation evidenced the onset of a new norovirus GII.4 variant, termed Sydney 2012. In Italy, ISGEV hospital-based surveillance revealed that this variant already circulated at low frequency in the winter season 2011-2012 and emerged definitively only in the late 2012. This lag-time pattern mirrors the findings reported elsewhere and suggests that the novel variant circulated at low prevalence before spreading globally.

FUNCTIONAL CHARACTERIZATION OF NOVEL AMINO ACID VARIANTS IN APOB IN FAMILIAL HYPOBETALIPOPROTEINEMIA

2013

Introduction. Familial Hypobetalipoproteinemia (FHBL) is a codominant disorder characterized by reduced levels of LDL and apolipoprotein B (apoB) in plasma. In approximately 50% of FHBL cases is due to mutations in APOB gene resulting in truncated apoBs of various size. Only a few missense mutations have been reported so far as the cause of FHBL. In vitro studies have shown that these mutations induce retention of the mutant apoB in the endoplasmic reticulum and impair the secretion of apoB-containing lipoproteins. We identi ed two novel amino acid variants (Thr26-27del and Tyr102Cys) located in the N-terminal 1000 amino acids of mature apoB in two hypocholesterolemic blood donors. Methods.…