Search results for "vault"

Chronic idiopathic hyperphosphatasia with unusual dental findings: a case report

2012

Chronic idiopathic hyperphosphatasia(CIH) or juvenile Paget disease is believed to be a distinct disease characterized by an increase in the serum alkaline phosphatase, cortical thickening and bowing of the long bones, especially the femora. It is a rare autosomal recessive bone disorder, with excessive bone resorption and bone formation. Skeletal malformations in the legs may cause problems in walking and may eventually result in short stature. The radiographic appearances include widening of the diaphyses, vertebral osteoporosis, acetabular protrusion, and thickening of the skull vault. Intensive bisphosphonate treatment prevented the development of deformity and disability but there is n…

CT and MR Imaging of Lesions of Skull Base and Cranial Vault

1989

The importance of CT in examinations of the skull base, including its role in the planning of operative or radiation therapy, has long been recognized (Liliequist and Forsell 1976; Bradac et al. 1977 a, b; 1978 a, b; Hammerschlag et al. 1977; Caille et al. 1977; Lohkamp et al. 1977; Huk and Schiefer 1978; Becker et al. 1978; Weinstein et al. 1978). In the present chapter we shall review the capabilities and limitations of this modality in the diagnosis of diseases involving the bony skull base and cranial vault. A more detailed discussion of specific tumor types may be found under the appropriate headings elsewhere in the book.

Combined surgical and prosthetic approach for rehabilitation of frontonasal defect using custom made titanium implant: a case report

2011

Cranial vault deformities as a sequelae to trauma may be as high as 70%. The basic indications for cranioplasty are improvement of disfigured aesthetics and to provide protection to the intra-cranial contents. The possibility of producing custom-made implants opened a new era in the reconstructive surgery of the craniofacial deformities. The outcome of craniofacial bone reconstruction is thought to be dependent on surgical skills, quality of adjacent soft tissues, size and location of the bone defect and choice of repair method. The use of autologous bone for craniofacial reconstruction may be restricted due to limited amounts of donor bone. Combined surgical and prosthetic rehabilitation o…

Proteomic analysis reveals a role for Bcl2-associated athanogene 3 and major vault protein in resistance to apoptosis in senescent cells by regulatin…

2014

Senescence is a prominent solid tumor response to therapy in which cells avoid apoptosis and instead enter into prolonged cell cycle arrest. We applied a quantitative proteomics screen to identify signals that lead to therapy-induced senescence and discovered that Bcl2-associated athanogene 3 (Bag3) is up-regulated after adriamycin treatment in MCF7 cells. Bag3 is a member of the BAG family of co-chaperones that interacts with Hsp70. Bag3 also regulates major cell-signaling pathways. Mass spectrometry analysis of the Bag3 Complex revealed a novel interaction between Bag3 and Major Vault Protein (MVP). Silencing of Bag3 or MVP shifts the cellular response to adriamycin to favor apoptosis. We…

Case Study of the Structural Behavior of a Catalan Bricks Masonry Vault

2015

Catalan vaults are a peculiar type of low thickness vaulted brick masonry structure. Knowledge of load-deflection response and load bearing capacity are important aspects to consider with the aim of preserving these structural members as part of the cultural heritage. In order to investigate these aspects, complete knowledge of the constituent materials and geometry (dimension, thickness, constructive section) is necessary in such a way as to predict the load-deflection response and the effective load-carrying capacity; the latter can be determined utilizing simplified models (limit analysis) or by means of a numerical analysis (finite element method). With this aim, the structural behaviou…

A case study of the structural behavior of a catalan bricks masonry vault

2014

The dammuso: constructive characters of the traditional stone buildings of the isle of Pantelleria (Sicily)

2019

Pantelleria, a volcanic island between Tunisia and Sicily, is characterized by a highly windy territory constantly hit by the sun. This harsh environment forced the inhabitants to build in an extremely effective way against the natural elements. This paper investigates constructive technologies, local materials, and phases of construction of the traditional rural houses, the dammuso, a Sicilian word meaning “vaulted-building”. It is a traditional passive cooling building characterized by a cubical shape covered by a vaulted-roof. This typology can be found almost everywhere in the isle, both old and pretty new, as the only one permitted. The minimum configuration unit is a cube made of bear…

The ‘false vaults’ in the architecture of Sicily

2015

Between the end of the 17th century and the first decades of the 18th, Sicily was struck by several violent earthquakes. The total and partial collapse of monumental buildings produced a global debate involving various aspects of construction practice. One of the central topics of discussion was the construction of domes and large vaulted structures. Some architects studied the possibility of using so-called ‘false vaults’, a kind of lightweight structure created with a wooden frame, reed mats, and plaster. The technique was probably known by the 16th century and was used in a few major monuments, such as the dome of the Palermo Cathedral, in the mid-17th century. It was only after the Eart…

Interventi su volte sottili di mattoni in foglio in Sicilia (Intervention on tiled vaults in Sicily)

2016

Recenti studi hanno confermato come la diffusione nella Sicilia occidentale delle volte sottili di mattoni in foglio (“realine”) sia avvenuta in maniera estesa dalla seconda metà del secolo XVIII ai primi decenni del Novecento, sia negli orizzontamenti e nelle scale dell'edilizia corrente, che con funzione portante e di soffittatura nelle architetture nobiliari. Per finalità di studio o professionali se ne sono analizzati i caratteri costruttivi, le costanti e le variabili, con verifiche su strutture che hanno superato indenni le prove del tempo. In laboratorio o nei cantieri sono state effettuate sperimentazioni accademiche ed interventi di recupero, con ricostruzioni parziali o totali e i…

Timbrel vaults in Sicily. Constructive techniques and intervention methodologies

2017

Tra le tante tipologie di volte riscontrate sul territorio siciliano finalizzate a coniugare economia e leggerezza senza perdere in sicurezza, vengono in questo studio analizzate quelle costituite da due, tre o quattro fogli di mattoni sottili uniti con gesso (volte realine secondo la definizione locale). Non si hanno notizie certe sull’origine di queste volte che, probabilmente introdotte dall’area iberica in Sicilia nella prima metà del XVIII secolo, evidenziano come un sistema costruttivo importato da aree geografiche spesso molto distanti possa essere reinterpretato in funzione dei materiali disponibili e della cultura edilizia locale. Ciò ha in più occasioni determinato soluzioni origi…