Search results for "very"

showing 7 items of 6927 documents

Changes in the Use Intention of Digital Wellness Technologies and Its Antecedents Over Time : The Use of Physical Activity Logger Applications Among …

2021

Physical inactivity has become a prevalent problem among elderly people. Although digital wellness technologies have been proposed as one promising solution to it, our understanding on the antecedents of the acceptance and use of these technologies among elderly people remains limited. In this study, our objective is to promote this understanding by examining the potential changes in the use intention of digital wellness technologies and its antecedents over time in the case of the young elderly segment and physical activity logger applications. We base this examination theoretically on UTAUT2 and empirically on survey data that is collected from 99 Finnish young elderly users of a physical…

young elderlyhyvinvointiteknologiaApplied psychologyPhysical activityutaut2mobiilipalvelutPartial least squares regressionpartial least squaresDigital Mobile Services for Everyday LifemobiilisovelluksetPsychologyikääntyneetfyysinen aktiivisuusdigital wellness technologiesphysical activity logger applications
researchProduct

Biodegradable Metal-Organic Framework-Based Microrobots (MOFBOTs).

2020

Microrobots and metal–organic frameworks (MOFs) have been identified as promising carriers for drug delivery applications. While clinical applications of microrobots are limited by their low drug loading efficiencies and the poor degradability of the materials used for their fabrication, MOFs lack motility and targeted drug delivery capabilities. The combination of these two fields marks the beginning of a new era; MOF‐based small‐scale robots (MOFBOTs) for biomedical applications. Yet, biodegradability is a major hurdle in the field of micro‐ and nanoswimmers including small‐scale robots. Here, a highly integrated MOFBOT that is able to realize magnetic locomotion, drug delivery, and selec…

zeolitic imidazolate frameworksMaterials scienceBiomedical EngineeringPharmaceutical ScienceNanotechnology02 engineering and technology010402 general chemistrybiodegradation01 natural sciencesBiomaterialsmetal–organic frameworksDrug Delivery SystemsNeoplasmsHumansMetal-Organic FrameworksBiodegradable metal021001 nanoscience & nanotechnologyControlled release0104 chemical sciencesMagnetic FieldsTargeted drug deliverySelective degradationDoxorubicindrug deliveryDrug deliverybiodegradation; drug delivery; metal–organic frameworks; microrobots; zeolitic imidazolate frameworksChemotherapeutic drugs0210 nano-technologymicrorobotsAdvanced healthcare materials
researchProduct

Chemical Composition of the Essential Oil of Bupleurum Fontanesii (Apiaceae) Growing Wild in Sicily and its Activity on Microorganisms Affecting Hist…

2016

Hydrodistillation of the flowers (BpFl) of and fruits (BpFr) of Bupleurum fontanesii Guss. ex Caruel gave two oils that were analyzed by GC and GC-MS. The main components were α-elemol (16.7%), caryophyllene oxide (16.4%) and heptacosane (15.9%) in BpFl, and spathulenol (16.8%), caryophylladienol I (13.2%) and α-elemol (12.8%) in BpFr. A good antimicrobial activity against several microorganisms, including Bacillus subtilis, Staphylococcus aureus, Fusarium oxysporum and Aspergillus niger, all infesting historical art craft, was also determined.

α-ElemolBupleurumAntifungal AgentsMicroorganismPlant ScienceBacillus subtilis01 natural scienceslaw.inventionlawVolatile componentDrug DiscoveryBotanyFusarium oxysporumOils VolatilePlant OilsSicilyEssential oilPharmacologyApiaceaeBacteriaBupleurum fontanesiibiology010405 organic chemistryDrug Discovery3003 Pharmaceutical ScienceAspergillus nigerFungiSpathulenolfood and beveragesGeneral MedicineComplementary and Alternative Medicine2708 DermatologyAntimicrobialbiology.organism_classificationAnti-Bacterial AgentsBupleurum0104 chemical sciences010404 medicinal & biomolecular chemistryCaryophyllene oxideComplementary and alternative medicineArtApiaceaeNatural Product Communications
researchProduct

New polysaccharide-polyaminoacid hydrogels: a suitable strategy for colon-specific drug delivery

2007

The aim of this study was to prepare and characterize novel hydrogels with polysaccharide–polyaminoacid structure, able to undergo an enzymatic hydrolysis in the colon and potentially useful for treating inflammatory bowel diseases (IBD). Starting materials were methacrylated dextran (DEX-MA) and methacrylated α,β-poly(N-2-hydroxyethyl)-DL-aspartamide (PHM). These polymers were photocrosslinked by exposure of their aqueous solutions at 313 nm without photoinitiators. Different samples, shaped as microparticles, were obtained as a function of polymer concentration and irradiation time. FT-IR analysis confirmed the occurrence of a co-crosslinking between DEX-MA and PHM in all experimental con…

αβ-Poly(N-2-hydroxyethyl)-DL-aspartamideBiodegradable hydrogelColon drug deliveryDextranPhotocrosslinking
researchProduct

Discovery of α2β1 integrin ligands : tools and drug candidates for cancer and thrombus

2011

α2β1-integriiniliganditintegriinitintegriinisalpaajatα2β1 integrinthrombusrational drug discoverysyöpäkollageenitliganditveritulppacollagen receptor integrinsfarmakoforitX-ray crystallography
researchProduct

Less is future: landscape as the key element for the “milieux” renaissance in the former East Germany

2013

Twenty-two years ago, Germany was reunified as a single state. Waste land, pollution and empty buildings are some of the problems that the people had to face, along with radical and painful political reorganization. The strong collective reaction to these environmental and social disasters was heart-warming. Hundreds of coordinated and collective actions of renovation in open spaces were carried out. People were involved in each level of the design process in order to decide the best way to improve and promote the heritage and identity of their landscape. Halle, Dessau, Leipzig, and Berlin are some examples explained in this paper which demonstrate that these successful massive actions are …

“Milieux” renaissance history heritage landscape comprehension cultural landscape landscape identity people’s involvement collective actions everyday territoriesSettore ICAR/15 - Architettura Del Paesaggio
researchProduct

La grammaire à l’école élémentaire française : un enseignement sous tension…

2022

La question de l’enseignement de la langue à l’école reste sensible en France et entraine régulièrement des débats et des controverses qui dépassent le cadre scolaire. La grammaire cristallise ces oppositions tant au niveau linguistique, didactique et pédagogique, politique, institutionnel, social… Nous sommes de fait face à un enseignement sous tension. Notre proposition tentera d’interroger et de croiser deux dimensions, les savoirs prescrits et les savoirs enseignés. Cette mise en interaction se fera selon deux axes: sur un axe diachronique, nous proposerons une analyse de quelques textes institutionnels qui se succèdent depuis vingt ans pour comprendre les attentes ministérielles dans u…

“UNESCO:CIENCIAS DE LAS ARTES Y LAS LETRAS”Linguistics and Languagepronoms anafòricsdiscovery-learninglaboratori de gramàticaexplicit knowledge of languagegrammar laboratoryanaphoric pronounsaprenentatge per descobrimentLanguage and Linguisticsconeixement explícit de la llenguaCaplletra. Revista Internacional de Filologia
researchProduct