Search results for "vine"

MINIMALIST THEORY OF FICTION AND THE ICTHINKING® METHOD AS A BACKGROUND FOR NEW INSIGHTS TO AUTISM

2021

The standard approach to conceptual understanding in the case of autism uses the distinction of abstract versus concrete thinking. This approach has its benefits but fails to explain all features of language use. For example, some concepts change their meaning in different contexts in contrast to concepts that are more rigid in their uses, such as mathematical concepts. This idea has its background in Minimalist theory of fiction (MTF), a theory that considers ‘skills to use words’ essential for understanding fiction, contrasting with theories that require pretending or make believe to understand fiction. From this background, the theory of Integrative Complexity (IC), and the method animat…

Systems thinking and adult cognitive development

2020

This chapter explores the links between scientific systems approaches and adult cognitive development. First, it describes the premises and basic concepts of systems thinking. It then continues to give an overview of the history of systems approach and the development of the main models and theories from its roots, which lie in the natural sciences. This is followed by an examination of the three systems paradigms, namely, Closed Systems, Open Systems, and Dynamic Systems and their implications to research and operational interests, in addition to their explanatory power in today’s world. Second part of the chapter focuses on describing the intersections between the Dynamic Systems paradigm…

Transformative Teaching and Learning Through Engaged Practice : Lecturers’ and Students’ Experiences in a University and Underserved Community Partne…

2018

peer-reviewed The Community Wellness, Empowerment, Leadership and Lifeskills (CWell) program is a two-year community-driven program developed in partnership between an underserved-community in Limerick City, and staff at the University of Limerick (UL), Ireland. This paper explores the transformative teaching and learning experiences that arose throughout the duration of the progam for the lecturers and students. Data were collected through interviews and focus groups with lecturers and students involved in the program. Students supported the notion of “learning differently” and focused around prior learning and attitude to learning, learning about learning and impact of learning. Lecturers…

Evidence for the presence of autoantibodies to the collagen-like portion of C1q in systemic lupus erythematosus.

1988

We investigated the connection between the C1q solid-phase binding assay (C1q SPBA) and double-stranded DNA antibodies, and analyzed the immune complex material in systemic lupus erythematosus (SLE) sera. Comparison with a new monoclonal assay for C1q-bearing immune complexes (the 242G3 assay) revealed that the immune complexes in SLE bind specifically to solid-phase C1q, and not to fluid-phase C1q. The C1q solid-phase binding activity sedimented as 7S IgG, was insensitive to DNase treatment, and could be selectively absorbed by C1q-coupled beads and by bovine serum albumin-anti-bovine serum albumin C1q beads, but not by DNA. Thus, antibodies to double-stranded DNA do not interfere in the C…

Topology-based goodness-of-fit tests for sliced spatial data

2023

In materials science and many other application domains, 3D information can often only be extrapolated by taking 2D slices. In topological data analysis, persistence vineyards have emerged as a powerful tool to take into account topological features stretching over several slices. In the present paper, we illustrate how persistence vineyards can be used to design rigorous statistical hypothesis tests for 3D microstructure models based on data from 2D slices. More precisely, by establishing the asymptotic normality of suitable longitudinal and cross-sectional summary statistics, we devise goodness-of-fit tests that become asymptotically exact in large sampling windows. We illustrate the test…

From Deep Learning to Deep University: Cognitive Development of Intelligent Systems

2018

Search is not only an instrument to find intended information. Ability to search is a basic cognitive skill helping people to explore the world. It is largely based on personal intuition and creativity. However, due to the emerged big data challenge, people require new forms of training to develop or improve this ability. Current developments within Cognitive Computing and Deep Learning enable artificial systems to learn and gain human-like cognitive abilities. This means that the skill how to search efficiently and creatively within huge data spaces becomes one of the most important ones for the cognitive systems aiming at autonomy. This skill cannot be pre-programmed, it requires learning…

Cognitive Mimetics for Designing Intelligent Technologies

2018

Design mimetics is an important method of creation in technology design. Here, we review design mimetics as a plausible approach to address the problem of how to design generally intelligent technology. We argue that design mimetics can be conceptually divided into three levels based on the source of imitation. Biomimetics focuses on the structural similarities between systems in nature and technical solutions for solving design problems. In robotics, the sensory-motor systems of humans and animals are a source of design solutions. At the highest level, we introduce the concept of cognitive mimetics, in which the source for imitation is human information processing. We review and discuss so…

In Vivo Imaging of Enteric Neuronal Networks in Humans Using Confocal Laser Endomicroscopy

2012

Interacting processes in protein coagulation

1999

A strong interest is currently focused on protein self-association and deposit. This usually involves conformational changes of the entire protein or of a fragment. It can occur even at low concentrations and is responsible for pathologies such as systemic amyloidosis, Alzheimer's and Prion diseases, and other neurodegenerative pathologies. Readily available proteins, exhibiting at low concentration self-association properties related to conformational changes, offer very convenient model systems capable of providing insight into this class of problems. Here we report experiments on bovine serum albumin, showing that the process of conformational change of this protein towards an intermedia…

Inflorescence-visiting insects of a functionally dioecious wild grapevine

2018

The wild grapevine [Vitis vinifera L. subsp. sylvestris (Gmelin) Hegi] is the Eurasian dioecious ancestral form of mostly monoecious domesticated cultivars (Vitis vinifera subsp. vinifera). There are different hypotheses about grapevine pollination, varying from insect to wind pollination to spontaneous self-pollination. The aim of this paper is to update our knowledge on the biology of the wild grapevine by studying the insects visiting their inflorescences. During the fieldworks, floral visitors were observed, captured and identified. The most frequent insects visiting both sexes of wild grapevine were beetles (55%) followed by bees (45%). The present study shows that although in vineyard…