Search results for "vins"

Exercise restores decreased physical activity levels and increases markers of autophagy and oxidative capacity in myostatin/activin blocked mdx mice

2013

The importance of adequate levels of muscle size and function and physical activity is widely recognized. Myostatin/activin blocking increases skeletal muscle mass but may decrease muscle oxidative capacity and can thus be hypothesized to affect voluntary physical activity. Soluble activin receptor IIB (sActRIIB-Fc) was produced to block myostatin/activins. Modestly dystrophic mdx mice were injected with sActRIIB-Fc or PBS with or without voluntary wheel running exercise for 7 wk. Healthy mice served as controls. Running for 7 wk attenuated the sActRIIB-Fc-induced increase in body mass by decreasing fat mass. Running also enhanced/restored the markers of muscle oxidative capacity and autoph…

Growth and differentiation factor 11 (GDF11): Functions in the regulation of erythropoiesis and cardiac regeneration

2015

International audience; Members of the TGF-β superfamily transduce their signals through type I and II receptor serine/threonine kinases. The binding of activins to activin type IIA (ActRIIA) or type IIB (ActRIIB) receptors induces the recruitment and phosphorylation of an activin type I receptor (ALK4 and/or ALK7), which then phosphorylates the Smad2 and Smad3 intracellular signaling proteins. The regulation of members of the TGF-β family is known to be complex, because many proteins able to bind the ligands and inhibit their activities have been identified. Growth and differentiation factor 11 (Gdf11) belongs to the TGF-β family. GDF11, like other members of the TGF-β superfamily, is prod…

Plant biodiversity in boreal wood-pastures : impacts of grazing and abandonment

2016

Vin, produits de la vigne et alimentation à Dijon à la fin du Moyen Âge

2019

International audience

Artighetsstrategier i muntlig språkfärdighet i de allmänna språkexamina

1997

Ludus in Fabula: Music and Play in Stravinsky's "The Rake's Progress" (1951)

2009

Tirer et porter : l’emploi des bovins au Néolithique. Apport de l’étude des phalanges 1

2011

International audience; Tirer et porter : l’emploi des bovins au Néolithique. Apport de l’étude des phalanges 1

La minéralité perçue dans le vin

2015

Article technique.; National audience; Beaucoup des aspects les plus fondamentaux et passionnants du vin demeurent conceptuellement insaisissables. Lorsque nous y sommes confrontés d’un point de vue sensoriel, nous pouvons avoir l’impression de bien connaître les attributs les plus abstraits du vin comme la qualité, la complexité et la minéralité, mais d’un point de vue scientifique nous savons très peu de chose sur ce que précisément ces termes signifient à la fois pour les professionnels et les consommateurs de vin. Par exemple, malgré l’intérêt actuel de la filière et des producteurs pour la perception de la minéralité dans le vin et l’utilisation de plus en plus fréquente de ce terme pa…

Importance of diet and prophylactic treatment on survival and immunity of polyphagous Arctia plantaginis (Arctiidae) larvae

2018

Diet is one of the major factors directly and indirectly influencing insect’s life history traits and risk of getting infected. Additionally the insect’s fitness is severely affected by the broad diversity of parasites they are exposed to. As a consequence insects have developed well-evolved defences. Behavioural responses include self-medication, the ability of insects to change dietary intake in response to an infection. When studying this ability it is of major importance to consider the insects natural diet range. In this thesis I investigated the effect of different host plants on fitness and immunocompetence of polyphagous Arctia plantaginis larvae and whether the larvae can therapeut…

Systemic blockade of ACVR2B ligands attenuates muscle wasting in ischemic heart failure without compromising cardiac function

2020

Signaling through activin receptors regulates skeletal muscle mass and activin receptor 2B (ACVR2B) ligands are also suggested to participate in myocardial infarction (MI) pathology in the heart. In this study, we determined the effect of systemic blockade of ACVR2B ligands on cardiac function in experimental MI, and defined its efficacy to revert muscle wasting in ischemic heart failure (HF). Mice were treated with soluble ACVR2B decoy receptor (ACVR2B-Fc) to study its effect on post-MI cardiac remodeling and on later HF. Cardiac function was determined with echocardiography, and myocardium analyzed with histological and biochemical methods for hypertrophy and fibrosis. Pharmacological blo…