Search results for "virtu"
showing 10 items of 1987 documents
Algo más que el adiós al marxismo. El XXVIII Congreso del PSOE y el derecho de autodeterminación
2021
El XXVIII Congreso del Partido Socialista Obrero Español, celebrado en mayo de 1979, ha sido recordado por la célebre renuncia de Felipe González a la Secretaría General. El PSOE se había reafirmado como marxista y González acababa de perder el debate nominalista sobre la definición del partido. Aquel impacto emocional y mediático permitió ocultar tras los fuegos de artificio otros debates de mayor trascendencia práctica que también se dieron cita en aquel encuentro. Entre ellos, el que tenía que ver con su modelo de política autonómica. Desde 1979 estaba en juego cómo iba a construirse el Estado de las Autonomías, y el PSOE tenía la oportunidad de establecer en la resolución sobre autonomí…
Probabilistic analysis of truss structures with uncertain parameters (virtual distortion method approach)
2004
A new approach for probabilistic characterization of linear elastic redundant trusses with uncertainty on the various members subjected to deterministic loads acting on the nodes of the structure is presented. The method is based on the simple observation that variations of structural parameters are equivalent to superimposed strains on a reference structure depending on the axial forces on the elastic modulus of the original structure as well as on the uncertainty (virtual distortion method approach). Superposition principle may be applied to separate contribution to mechanical response due to external loads and parameter variations. Statically determinate trusses dealt with the proposed m…
Molecular topology applied to the discovery of 1-benzyl-2-(3-fluorophenyl)-4-hydroxy-3-(3-phenylpropanoyl)-2H-pyrrole-5-one as a non-ligand-binding-p…
2014
We report the discovery of 1-benzyl-2-(3- fluorophenyl)-4-hydroxy-3-(3-phenylpropanoyl)-2H-pyrrole- 5-one as a novel non-ligand binding pocket (non-LBP) antagonist of the androgen receptor (AR) through the application of molecular topology techniques. This compound, validated through time-resolved fluorescence resonance energy transfer and fluorescence polarization biological assays, provides the basis for lead optimization and structure−activity relationship analysis of a new series of non-LBP AR antagonists. Induced-fit docking and molecular dynamics studies have been performed to establish a consistent hypothesis for the interaction of the new active molecule on the AR surface. Refereed/…
Antiproliferative properties and g-quadruplex-binding of symmetrical naphtho[1,2-b:8,7-b’]dithiophene derivatives
2021
Background: G-quadruplex (G4) forming sequences are recurrent in telomeres and promoter regions of several protooncogenes. In normal cells, the transient arrangements of DNA in G-tetrads may regulate replication, transcription, and translation processes. Tumors are characterized by uncontrolled cell growth and tissue invasiveness and some of them are possibly mediated by gene expression involving G-quadruplexes. The stabilization of G-quadruplex sequences with small molecules is considered a promising strategy in anticancer targeted therapy. Methods: Molecular virtual screening allowed us identifying novel symmetric bifunctionalized naphtho[1,2-b:8,7-b’]dithiophene ligands as interesting ca…
<title>Face modeling: a real-time embedded implementation of a stereovision algorithm</title>
2001
The problem to acquire 3D data of human face can be applied in face recognition, virtual reality, and many other applications. It can be solved using stereovision. This technique consistes in acquiring data in three dimensions from two cameras. The aim is to implement an algorithmic chain which makes it possible to obtain a three-dimensional space from two two-dimensional spaces: two images coming from the two cameras. Several implementations have already been considered. We propose a new simple realtime implementation, based on a multiprocessor approach (FPGA-DSP) allowing to consider an embedded processing. Then we show our method which provides depth map of face, dense and reliable, and …
A Theoretical Learning Model Combining Stochastic Cellular Automata and Economic Indicators to Simulate Land Use Change
2015
The study of change in land use has been included in territorial planning to inform spatial planners and policy makers of the possible developments they face in order to optimize future management decisions. In this paper the authors present the core of an original learning model coupling stochastic Cellular Automata and economic indicators to simulate the land use change. This model is an important step in building an “environmental virtual laboratory” to explore, explain and forecast land use change.
Explaining the relationship between socially responsible products and the operations of the firm: The case of equine assisted therapy
2018
Abstract Although there is a growing interest in social responsibility in research as well as in practice, the majority of studies on corporate social responsibility do not explicitly investigate operations management issues when adopting socially responsible practices under the “people” pillar of sustainability. This paper, dealing with the theme of social responsibility in operations management, aims at clarifying the complex relationship between socially responsible product/service and the operations of the company. The empirical context of the study is the sport industry, where the attention to social issues is well established. We used a mixed theoretical-empirical approach to develop …
Lettura stratigrafica degli elevati e restituzione 3d del monumento (VII-VIII secolo)
2009
Il contributo concerne lo studio ricostruttivo della chiesa paleocristiana nella seconda fase di vita dell'edificio. L'ipotesi ricostruttiva, e il modello 3D, si è basata sullo studio delle fonti dirette: rilievo, dati di scavo archeologico e lettura stratigrafica degli elevati. The contribution concerns the reconstructive study of the early Christian church in the second phase of the building's life. The reconstructive hypothesis, and the 3D model, was based on the study of direct sources: survey, archaeological excavation data and stratigraphic reading of the elevations.
Architettura altomedievale nel Santuario di San Michele: analisi stratigrafica degli elevati e studio ricostruttivo 3D
2012
Il Santuario di San Michele a Monte Sant’Angelo (FG) costituisce uno dei più importanti e antichi luoghi della cristianità occidentale. La sede del culto riservato all’Angelo è posta all’interno di una Caverna situata a metà del fianco settentrionale del rilievo montuoso sul cui pianoro si estende il centro abitato. Il contributo riguarda lo studio architettonico, dal rilievo alla lettura stratigrafica muraria fino alla ricostruzione virtuale, del monumento di età longobarda The Sanctuary of San Michele in Monte Sant’Angelo (FG) is one of the most important and ancient places of Western Christianity. The seat of the cult reserved for the Angel is placed inside a Cave located in the middle o…
Alle Wege Führen Zum Text
2016
The intention of this chapter is to review the development of linguistic research during the twentieth century in Europe and the United States, in order to show that the genesis of text linguistics as a comprehensive theoretical framework was necessary, considering the events from a post-eventum perspective. Firstly, structural linguistics is presented as well as its main exponents; secondly, generative linguistics is discussed; thirdly, the genesis and the development of text linguistics is presented. Concerning the structural linguistics, the key issues investigated by 4 linguists (namely, de Saussure, Benveniste, Hjelmslev and Bloomfield) are summarized. Concerning the generative linguis…