Search results for "virtu"
showing 10 items of 1987 documents
A convolutional neural network for virtual screening of molecular fingerprints
2019
In the last few years, Deep Learning (DL) gained more and more impact on drug design because it allows a huge increase of the prediction accuracy in many stages of such a complex process. In this paper a Virtual Screening (VS) procedure based on Convolutional Neural Networks (CNN) is presented, that is aimed at classifying a set of candidate compounds as regards their biological activity on a particular target protein. The model has been trained on a dataset of active/inactive compounds with respect to the Cyclin-Dependent Kinase 1 (CDK1) a very important protein family, which is heavily involved in regulating the cell cycle. One qualifying point of the proposed approach is the use of molec…
TeamSim: An Educational Micro-World for the Teaching of Team Dynamics
2008
In this paper we present an educational micro-world in which a learner can manipulate variables affecting the efficiency with which a team adapts to its environment. These include the structure of hierarchical relations within the team, the structure of the communications network, and other environmental parameters. Using the micro-world, the learner can design experiments (simulations) exploring notions in the dynamics of small groups. A freeware version of TeamSim is available from http:// laral.istc.cnr.it/gigliotta/.
Risposta di strutture a parametri incerti sotto forzanti dinamiche aleatorie
2005
Obiettivo del presente lavoro è la valutazione della risposta dinamica di strutture reticolari elastico-lineari, isostatiche, con incertezze nei parametri geometrici e/o meccanici
Digital Technologies for virtual recomposition. The case study of Serpotta stuccoes.
2014
The matter that lies beneath the smooth and shining surface of stuccoes of the Serpotta family, who used to work in Sicily from 1670 to 1730, has been thoroughly studied in previous papers, disclosing the deep, even if empirical, knowledge of materials science that guided the artists in creating their masterworks. In this work the attention is focused on the solid perspective and on the scenographic sculpture by Giacomo Serpotta, who is acknowledged as the leading exponent of the School. The study deals with some particular works of the artist, the so-called “teatrini” (Toy Theater), made by him for the San Lorenzo Oratory in Palermo. On the basis of archive documents and previous analogica…
Les juristes des années 30 et la question des droits du réalisateur d’oeuvres cinématographiques : une approche juridico-historique, à travers l’exem…
2017
La question de la paternité des oeuvres cinématographiques a été souvent débattue au cours des années 30. Elle fournit aujourd’hui encore au juriste et à l’historien de l’art une illustration particulièrement intéressante de la difficulté pour le droit d’appréhender ce qui fait l’essence d’une expression artistique spécifique, comme le cinéma, et en conséquence d’en déterminer les auteurs. Avant la loi de 1957, qui a reconnu la paternité du metteur en scène, la tendance jurisprudentielle était nettement en faveur de la thèse du producteur comme auteur ou coauteur du film. Les raisons à cet état des choses sont diverses, la principale étant la place centrale du producteur dans l’« entreprise…
The Feast of Life or the Feast of Reason – Kierkegaard Versus Plato
2011
The article consists of three sections. The first section “Dialogue at the intersection of literature and philosophy” analyzes the fundamental differences between the two modes of human intellectual activity – philosophy and literature on the basis of Anna-Teresa Tymieniecka’s philosophy. Nevertheless, the intersection is possible in the form of dialogue. The second chapter “Negative existential maeutics” is dedicated to Kierkegaard’s conception of existential maeutics in comparison with the Socratic maeutics. The stress is put upon its negative characteristics – the distance, the interruption, the situation of existential shock. These restrictions are necessary to allow the participants’ s…
Usability Challenges in Surgical Simulator Training
2009
Surgical virtual reality simulators have been taken into use in order to improve surgical skills training. Emergence of simulators increases the need for research and knowledge related to usability of medical simulators. In this study usability of laparoscopic surgical simulator was researched experimentally through combined analysis. Data was gathered with heuristic evaluation, questionnaires, and interviews as well as recorded simulator parameters. Results suggest that the surgical simulator could be more efficient learning and training tool if usability issues such as support and error prevention were reconsidered in more detail. There also seem to be grounds for connecting user support …
La cornice Ionica del tempio G di Selinunte. Rilievo e interpretazione per la ricostruzione virtuale.
2013
This research is focused on the virtual reconstruction of the Ionic cornice of temple G of Selinunte, as a case study for the definition of a virtual reconstruction method of collapsed walls elements in archaeological contexts. The complexity of the ruins of the temple suggested a thorough archaeological analysis of the fragments of the Ionic cornice that made it possible to identify traces of the construction process left by stonecutters during the worksite such as unfinished surfaces. The study of these surfaces, together with the dimensional data surveyed, provided the information to reposition the fragments in their supposed original position, and thus develop a virtual reconstruction o…
Process and technology challenges in swift-starting virtual teams
2007
Originally published in the journal Information & Management : http://www.sciencedirect.com/science/journal/03787206 Virtual teams often face tight schedules and a need to start quickly and perform instantly. The goal of our study was to enhance understanding of the challenges faced by such teams. We used time–interaction–performance theory as the framework for following the processes and functions within virtual teams working on a systems development task. Our study provided a detailed examination of the group process, applied to virtual teams working under time pressure. The challenges faced by virtual teams in such settings showed that teams must work to enhance their effectiveness in mu…
Représentation hybride du modèle numérique pour la gestion d'un patrimoine bâti dit ancien
2013
International audience; Ce projet de recherche explore et repousse les limites inhérentes à la représentation numérique du bâti ancien dans la préparation et le suivi de travaux de rénovation. A Cluny, l'Ecole Nationale Supérieure des Arts et Métiers est logée en partie dans les bâtiments de l'ancienne abbaye clunisienne. La représentation numérique d'un bâtiment permet d'archiver la connaissance tout au long de son cycle de vie. L'édifice, datant du XVIIIème siècle, est classé aux monuments historiques. En matière de rénovation les opérations sont strictement encadrées. L'étude de cas portera sur l'isolation intérieure d'un bureau au niveau de la baie ancienne. Elle consiste en l'ajout d'u…