Search results for "virtu"

showing 10 items of 1987 documents

Design, Synthesis, and Evaluation of New Tripeptides as COX-2 Inhibitors

2013

Cyclooxygenase (COX) is a key enzyme in the biosynthetic pathway leading to the formation of prostaglandins, which are mediators of inflammation. It exists mainly in two isoforms COX-1 and COX-2. The conventional nonsteroidal anti-inflammatory drugs (NSAIDs) have gastrointestinal side effects because they inhibit both isoforms. Recent data demonstrate that the overexpression of these enzymes, and in particular of cyclooxygenases-2, promotes multiple events involved in tumorigenesis; in addition, numerous studies show that the inhibition of cyclooxygenases-2 can delay or prevent certain forms of cancer. Agents that inhibit COX-2 while sparing COX-1 represent a new attractive therapeutic deve…

chemistry.chemical_classificationGene isoformVirtual screeningMolecular modelbiologyArticle SubjectCancerGeneral MedicineTripeptidePharmacologymedicine.disease_causemedicine.diseaseBiochemistryCOX-2 inhibitorsEnzymechemistrymedicinebiology.proteinCyclooxygenaseCarcinogenesisMolecular BiologyResearch Article
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Application of Molecular Topology to the Prediction of the Reaction Yield and Anticancer Activity of Imidazole and Guanidine Derivatives

2013

In this study molecular topology based QSAR has been applied to predict the reaction yield and anticancer activity of 18 imidazole and guanidine derivatives. Four properties were evaluated, namely reaction yield, anti prostatic-cancer activity, anti breast-cancer activity and anti lung-cancer activity. The four models have been validated by both internal and cross validation, and also by randomness tests. The results obtained are in full agreement with the experimental results and confirm the precision, accuracy and robustness of the method followed. After carrying out a virtual screening upon such models, new imidazole and guanidine derivatives with potential anticancer activity are propos…

chemistry.chemical_compoundVirtual screeningQuantitative structure–activity relationshipchemistryStereochemistryImidazoleMultiple linear regression analysisMolecular topologyCombinatorial chemistryGuanidine derivativesInternational Journal of Chemoinformatics and Chemical Engineering
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Le reti della buona morte

2017

Il saggio indaga le modalità di rappresentazione della morte a partire da siti internet dedicati e ai "gadget" in vendita on line per il corredo funerario

cimiteri virtualimorteimprese funebri on line
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Impact of the knowledge society in the university and in scientific communication

2014

Over the last two decades, as a result of the introduction and intensive use of technologies for information and general knowledge, especially from the internet, the university is living in a process of complete transformation that affects it´s academic and organizational structures as well as the conception of educational methodology. The ICTs have demonstrated a need to establish coherent institutional strategies in their use and application, along with the possibility to expand the sphere of institutional action, in regards to general access to higher education. All of this shows an existing change from a model of education based on the transmission of knowledge, that was rather limited …

ciència obertaEducación superior; sociedad del conocimiento; e-learning; acceso abierto; ciencia abierta; altmetricaltmetriceducación superiorsocietat del coneixementWeb-based instructionEnseñanza virtualopen sciencePedagogy; education; Communicatione-learningciencia abiertaopen accesseducationPedagogyCommunicationpedagogía; educación; comunicacióneducació superiorcomunicaciónaccés obertknowledge societyacceso abiertoaltmetricsEnsenyament virtualsociedad del conocimientohigher educationpedagogíaeducación
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Mejoras basadas en heurísticas para la percepción de estímulos en simuladores de realidad virtual y realidad aumentada

2023

Los simuladores tratan de hacer creer a los usuarios que están viviendo una situación ajena a su realidad. Habitualmente los sentidos estimulados por los simuladores son el visual, el auditivo y el táctil, este último mediante la instalación de elementos con los que el usuario interactúa, como un volante, un joystick o incluso una cabina de control completa. Otros sentidos, como el olfato, la propiocepción o el vestibular (sentido del movimiento), suelen estimularse menos habitualmente. De todos los sentidos, la presente tesis doctoral se focaliza en el sentido del movimiento. La manera habitual de introducir estímulos de movimiento en usuarios de simuladores es mediante plataformas de movi…

claves de movimientosimuladorplataforma de movimientorealidad aumentadaUNESCO::MATEMÁTICAS::Ciencia de los ordenadores::InformáticasimulaciónUNESCO::CIENCIAS TECNOLÓGICASrealidad virtualheurísticas
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A gearbox model for processing large volumes of data by using pipeline systems encapsulated into virtual containers

2020

Software pipelines enable organizations to chain applications for adding value to contents (e.g., confidentially, reliability, and integrity) before either sharing them with partners or sending them to the cloud. However, the pipeline components add overhead when processing large volumes of data, which can become critical in real-world scenarios. This paper presents a gearbox model for processing large volumes of data by using pipeline systems encapsulated into virtual containers. In this model, the gears represent applications, whereas gearboxes represent software pipelines. This model was implemented as a collaborative system that automatically performs Gear up (by using parallel patterns…

cloud storageCloud storageComputer Networks and CommunicationsComputer scienceDistributed computingcontinuous deliveryCloud computing02 engineering and technologyVirtual containersSoftwareIn-memory storage0202 electrical engineering electronic engineering information engineeringParallel patternssoftware pipelinesInformáticabusiness.industryvirtual containers020206 networking & telecommunicationsPipeline (software)Cloud storage; Continuous delivery; In-memory storage; Parallel patterns; Software pipelines; Virtual containersPipeline transportin-memory storageContinuous deliveryHardware and ArchitectureSoftware deploymentparallel patternsContainer (abstract data type)020201 artificial intelligence & image processingbusinessCloud storageSoftwareSoftware pipelinesFuture Generation Computer Systems
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Designing a Low-Fat Food Packaging: Comparing Consumers’ Responses in Virtual and Physical Shopping Environments

2021

This paper aims to test to what extent emotional responses towards a low-fat product presented virtually converge with emotional responses toward this product when presented physically. Second, we want to probe if low-order emotions (physiological/unconscious responses) and high-order emotions (cognitive/conscious responses) converge to explain healthy product choices. To this end, 83 young participants were engaged in our experiment. Two packaging design variables were manipulated with the help of a real company (the color and the message), so that six different packages were created. Two different buying contexts were simulated: A virtual context and a physical context. Physiological resp…

cognitionHealth (social science)Unconscious mindpackagingEye muscleContext (language use)Plant Scienceemotionslcsh:Chemical technologyHealth Professions (miscellaneous)MicrobiologyArticlePhysical context0502 economics and business0501 psychology and cognitive scienceslcsh:TP1-1185050102 behavioral science & comparative psychologyProduct (category theory)physical05 social sciencesCognitionPhysiological responsesTest (assessment)050211 marketingvirtualPsychologyFood ScienceCognitive psychologyFoods
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The influence of virtual reality in e-commerce

2019

[EN] The development of virtual reality (VR), together with other technological innovations will shape the future of e-retailing. This research studies the effectiveness of different VR formats and devices in a virtual store environment, namely V-commerce. This study proposes and test a conceptual model that analyses the relations between sense of presence, brand recall and purchase intention, while also going deeper into their antecedents. Our findings suggest differences in purchase intention depending on VR format and device used. No differences are shown in sense of presence and affect by VR format and device. Our tested model suggests a dual route of influence of VR on consumers' purch…

comercio electrónicoEXPRESION GRAFICA EN LA INGENIERIAcomerç virtualElectronic commercecomercio virtualE-commerceE-commerceVirtual realityrealidad virtualexperiencia virtualVirtual realitycomerç electrònicPolitical science0502 economics and businesse-commerceHead-mounted displayrealitat virtualvirtual experienceMarketingbusiness.industry05 social sciencesSense of presencesensación de presenciaMental healthv-commerceManagementhead-mounted displayVirtual experienceWork (electrical)sense of presencesensació de presènciavirtual reality050211 marketingChristian ministrybusinessexperiència virtualV-commerce050203 business & managementJournal of Business Research
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L'instrumentalisation du don et de la lutte pour la reconnaissance dans les communautés en ligne

2013

International audience

communauté virtuelle[SHS.INFO]Humanities and Social Sciences/Library and information sciencesreconnaissance[ SHS.INFO ] Humanities and Social Sciences/Library and information sciencesfracture numérique[SHS.INFO] Humanities and Social Sciences/Library and information sciencesComputingMilieux_MISCELLANEOUS
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L'identité en ligne: un alter ego numérique.

2011

International audience

communication en ligne[ SHS ] Humanities and Social Sciencesidentité virtuelle[SHS] Humanities and Social SciencesComputingMilieux_MISCELLANEOUSlinguistique[SHS]Humanities and Social Sciences
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