Search results for "visceral"

showing 10 items of 124 documents

Un caso di Leishmaniosi viscerale progressiva: ruolo del color Doppler nella diagnosi

2008

Leishmaniosi viscerale ecografia colorDoppler
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In vivo and in vitro cytokine profiles and mononuclear cell subsets in sicilian patients with active visceral leishmaniasis

1995

Sera from Sicilian patients with confirmed visceral leishmaniasis (Leishmania donovani infantum) were analysed at the moment of the diagnosis, during the course of the disease and after clinical recovery, for the concentration of IL-10, IFN-gamma, IL-4 and IL-2. The results show high concentrations of IL-10 and IFN-gamma in the sera at the beginning of infection that return to the normal range following successful chemotherapy. By contrast, PBMC stimulated in vitro with Ag and mitogen produced low levels of IL-10 and IFN-gamma when collected at the time of the diagnosis and normal levels when assayed after recovery. IL-2 was undetected in the sera and was significantly reduced in the supern…

MaleCD3medicine.medical_treatmentImmunologyAntigens ProtozoanBiochemistryPeripheral blood mononuclear cellAntigenIn vivomedicineAnimalsHumansImmunology and AllergyMacrophagePhytohemagglutininsSicilyMolecular BiologybiologyHematologymedicine.diseaseStimulation ChemicalRatsVisceral leishmaniasisCytokineCase-Control StudiesImmunologyDisease ProgressionLeukocytes Mononuclearbiology.proteinLeishmaniasis VisceralFemaleCD8Cytokine
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Cut-off points of the visceral adiposity index (VAI) identifying a visceral adipose dysfunction associated with cardiometabolic risk in a Caucasian S…

2011

Abstract Background The Visceral Adiposity Index (VAI) is a sex-specific mathematical index, based on Waist Circumference (WC), Body Mass Index (BMI), triglycerides (TG) and HDL cholesterol (HDL) levels, indirectly expressing visceral adipose function and insulin sensitivity. Our aim was to find the optimal cut-off points of VAI identifying a visceral adipose dysfunction (VAD) associated with cardiometabolic risk in a Caucasian Sicilian population. Methods Medical check-up data of 1,764 Primary Care patients (PC patients) were retrospectively and cross-sectionally examined using a receiver-operating characteristic (ROC) curve to determine appropriate stratified-for-age cut-off of VAI, for t…

MaleCross-sectional studyEndocrinology Diabetes and MetabolismClinical BiochemistrySettore MED/13 - EndocrinologiaEndocrinologyReference ValuesRisk Factorscardiometabolic riskPrevalenceMyocardial infarctionSicilylcsh:RC620-627Aged 80 and overMetabolic Syndromeeducation.field_of_studyMiddle Agedlcsh:Nutritional diseases. Deficiency diseasesCardiovascular DiseasesCardiologyvisceral adipose dynsfunctionFemaleAdultmedicine.medical_specialtyWaistAdolescentPopulationVisceral adiposity index VAI Obesity cardiometabolic risk visceral adipose dynsfunctionClinical nutritionIntra-Abdominal FatWhite PeopleYoung AdultInternal medicineDiabetes mellitusmedicineHumansBody Weights and MeasuresObesitycardiovascular diseaseseducationAgedRetrospective StudiesBiochemistry medicalbusiness.industryResearchBiochemistry (medical)medicine.diseaseVAIEndocrinologyCross-Sectional StudiesDiabetes Mellitus Type 2Metabolic syndromebusinessBody mass indexLipids in Health and Disease
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Pasireotide treatment reduces cardiometabolic risk in Cushing’s disease patients: an Italian, multicenter study

2018

Purpose: Patients with Cushing’s disease (CD) experience metabolic alterations leading to increased cardiovascular mortality. Recently, the visceral adiposity index (VAI) has been proposed as a marker of visceral adipose tissue dysfunction (ATD) and of the related cardiometabolic risk. We aimed to evaluate the impact of 12-month pasireotide treatment on cardiometabolic risk in CD patients. Methods: This is a multicentre, prospective, and observational study. Sixteen CD patients, referred to the Endocrine Units of the University Hospitals of Messina, Napoli, Padova, and Palermo (Italy), successfully treated with pasireotide for 12 month have been enrolled. In all patients, we assessed anthro…

MaleEndocrinology Diabetes and MetabolismCardiometabolic risk Cushing’s disease hypercortisolism pasireotide visceral adiposity indexLongitudinal StudieDisease030204 cardiovascular system & hematologySettore MED/13 - Endocrinologiachemistry.chemical_compound0302 clinical medicineEndocrinologyRisk FactorsMedicineLongitudinal StudiesProspective StudiesAdiposityFramingham Risk ScoreCushing’s diseaseCushing’s diseaseMiddle AgedPasireotideDiabetes and MetabolismHeart DiseaseItalyAtherosclerosiObesity AbdominalFemaleSomatostatinHumanAdultmedicine.medical_specialtyWaistHeart DiseasesHypercortisolism030209 endocrinology & metabolismIntra-Abdominal Fat03 medical and health sciencesMetabolic DiseasesInternal medicineDiabetes mellitusCardiometabolic risk; Cushing’s disease; Hypercortisolism; Pasireotide; Visceral adiposity index; Endocrinology Diabetes and Metabolism; EndocrinologyHumansPituitary ACTH Hypersecretionbusiness.industryRisk FactorCushing's diseaseAnthropometryAtherosclerosismedicine.diseasePasireotideCardiometabolic riskMetabolic DiseaseVisceral adiposity indexProspective StudiechemistryObservational studybusiness
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Knowledge, stigma, health seeking behaviour and its determinants among patients with post kalaazar dermal leishmaniasis, Bihar, India

2018

Background Lesishmaniasis is a neglected tropical disease endemic in Bihar, India. Inappropriate health seeking behaviour of post kala-azar dermal leishmaniasis (PKDL) patients may increase the disease duration, severity and transmissibility. Simultaneously, lack of knowledge and perceived stigma may also increase the length of delay in receiving treatment. This ultimately effects the kala-azar elimination program. Methods A cross sectional study was conducted in 120 confirmed PKDL patients, aged 18 years and older. Data related to knowledge and health seeking behaviour was collected by a pre-tested questionnaire. EMIC stigma scale was used for assessing the perceived stigma. Patients were …

MaleHealth Knowledge Attitudes PracticePediatricsTime FactorsSocial stigmaCross-sectional studyHealth Care ProvidersHealth BehaviorSocial Stigmalcsh:MedicineDiseaseDisease VectorsPathology and Laboratory Medicine0302 clinical medicineInformed consentZoonosesMedicine and Health SciencesMedicinePublic and Occupational Health030212 general & internal medicineYoung adultlcsh:ScienceLeishmaniasisMultidisciplinaryMiddle AgedInfectious DiseasesLeishmaniasis VisceralFemaleBehavioral and Social Aspects of HealthResearch ArticleNeglected Tropical DiseasesAdultmedicine.medical_specialtyAdolescentPatients030231 tropical medicineAntiprotozoal AgentsIndiaLeishmaniasis CutaneousStigma (botany)DermatologySkin DiseasesYoung AdultKala-Azar03 medical and health sciencesSigns and SymptomsDiagnostic Medicineparasitic diseasesParasitic DiseasesHumansAgedProtozoan Infectionsbusiness.industrylcsh:RBiology and Life SciencesTropical diseasePatient Acceptance of Health CareTropical Diseasesmedicine.diseaseInsect VectorsSand FliesHealth CareSpecies InteractionsCross-Sectional StudiesLesionslcsh:QbusinessLeishmania donovaniPatient educationPLOS ONE
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A 6 day course of liposomal amphotericin B in the treatment of infantile visceral leishmaniasis: the Italian experience

2004

Objectives To evaluate in a retrospective analysis the efficacy and safety of a 6 day course of liposomal amphotericin B (L-AmB) in infantile cases of Mediterranean visceral leishmaniasis (VL) diagnosed over a 10 year period in Italy. Patients and methods Patients included were diagnosed as having VL consecutively admitted from December 1992 to December 2001 at four main referral children's hospitals in Italy and treated with six intravenous doses of 3 mg/kg L-AmB given on days 1-5 and 10 (a total dose of 18 mg/kg). Demographic data, nutritional status, underlying diseases, clinical and laboratory findings, and therapy outcome were considered. Results A total of 164 HIV-negative children (m…

MaleMicrobiology (medical)medicine.medical_specialtyAdolescentFeverAntiprotozoal AgentsFluorescent Antibody TechniqueNutritional Statusitaly; leishmania infantum; therapyBone MarrowRecurrenceAmphotericin BInternal medicineAmphotericin BmedicineHumansPharmacology (medical)ChildAdverse effectleishmaniasisRetrospective StudiesPharmacologyDrug Carriersbiologybusiness.industryInfantRetrospective cohort studyLeishmaniasismedicine.diseasebiology.organism_classificationSurgeryRegimenTreatment OutcomeInfectious DiseasesVisceral leishmaniasisItalyEl NiñoChild PreschoolLiposomesLeishmaniasis VisceralFemaleLeishmania infantumbusinessmedicine.drug
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Mid- and Longer-term Follow up of Chimney and/or Periscope Grafts and Risk Factors for Failure

2016

Objective The aim was to report on chimney and periscope grafts (CPGs) and their mid- and longer-term outcomes when they are used to preserve reno-visceral artery (RVA) perfusion in endovascular repair of pararenal (PRAAs) or thoraco-abdominal aortic aneurysm (TAAAs). In addition, factors associated with CPG failure are presented. Limited data exist on the outcomes of CPGs, and mid- and long-term results are generally not reported. Methods This was a prospective study in a cohort of 100 patients with PRAA (69) or TAAA (31). A total of 224 (mean 2.24 per patient) RVAs were preserved with 136 (61%) chimney and 88 (39%) periscope grafts. CPGs were constructed mainly using self expandable stent…

MalePercutaneousmedicine.medical_treatment030204 cardiovascular system & hematologyEndovascular aneurysm repairSettore MED/22 - Chirurgia VascolareAortic aneurysm0302 clinical medicineRenal ArteryRisk FactorsOcclusion030212 general & internal medicineTreatment FailureProspective cohort studyAortaPararenal aortic aneurysm10042 Clinic for Diagnostic and Interventional RadiologyReno2746 SurgeryAortic AneurysmFemaleRadiologyCardiology and Cardiovascular Medicinemedicine.medical_specialty610 Medicine & health2705 Cardiology and Cardiovascular Medicine03 medical and health sciencesEndovascular aneurysm repairabdominal aortic aneurysmAneurysmChimney and periscope graftChimney and periscope graft; Complex aortic aneurysm; Endovascular aneurysm repair; Pararenal aortic aneurysm; Reno-visceral arteries; Thoraco-abdominal aortic aneurysm; Cardiology and Cardiovascular Medicine; SurgerymedicineHumansAgedRetrospective StudiesReno-visceral arterieThoraco-abdominal aortic aneurysmbusiness.industryComplex aortic aneurysmStentRetrospective cohort studyThoracomedicine.diseaseSurgeryvisceral arteriesSurgeryVascular GraftingbusinessFollow-Up Studies
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Arginase activity in the blood of patients with visceral leishmaniasis and HIV infection.

2013

Background Visceral leishmaniasis is a parasitic disease associated with high mortality. The most important foci of visceral leishmaniasis in Ethiopia are in the Northwest and are predominantly associated with high rates of HIV co-infection. Co-infection of visceral leishmaniasis patients with HIV results in higher mortality, treatment failure and relapse. We have previously shown that arginase, an enzyme associated with immunosuppression, was increased in patients with visceral leishmaniasis and in HIV seropositive patients; further our results showed that high arginase activity is a marker of disease severity. Here, we tested the hypothesis that increased arginase activities associated wi…

MaleViral Diseasesmedicine.medical_treatmentEnzyme MetabolismHIV InfectionsParasite loadBiochemistrySeverity of Illness Index0302 clinical medicineBlood plasmaSUPPRESSOR-CELLSMACROPHAGESPLASMA AMINO-ACIDS0303 health sciencesCoinfectionPARASITOLOGYlcsh:Public aspects of medicineImmunosuppression11 Medical And Health SciencesIMMUNODEFICIENCY-VIRUS TYPE-13. Good healthEnzymesSEROPOSITIVE PATIENTSArginaseInfectious DiseasesCoinfectionMedicineLeishmaniasis VisceralBiological MarkersLife Sciences & BiomedicineResearch ArticleNeglected Tropical DiseasesAdultlcsh:Arctic medicine. Tropical medicineAdolescentlcsh:RC955-962030231 tropical medicineINHIBITIONPeripheral blood mononuclear cellMECHANISMS03 medical and health sciencesYoung AdultDONOVANITropical MedicinemedicineParasitic DiseasesACTIVATED GRANULOCYTESHumansAdolescent; Adult; Arginase/blood; Biological Markers/blood; Coinfection/diagnosis; Coinfection/pathology; Cross-Sectional Studies; Ethiopia; HIV Infections/complications; HIV Infections/diagnosis; Humans; Leishmaniasis Visceral/complications; Leishmaniasis Visceral/diagnosis; Male; Severity of Illness Index; Young AdultBiology030304 developmental biologyScience & TechnologyArginasebusiness.industryPublic Health Environmental and Occupational HealthLeishmaniasislcsh:RA1-127006 Biological Sciencesmedicine.diseaseVisceral leishmaniasisCross-Sectional StudiesImmunologyEthiopiabusinessBiomarkersRESPONSES
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The current version of the visceral adiposity index is not suitable for application in pediatric populations: comments on the article by Al-Daghri et…

2014

The current version of the visceral adiposity index is not suitable for application in pediatric populations: comments on the article by Al-Daghri et al .

MaleVisceral Adiposity IndexGerontologyIndex (economics)Anthropometrybusiness.industryeducationMEDLINEIntra-Abdominal FatPediatrics Perinatology and Child HealthHumansMedicineFemalebusinessAdiposityPediatric Research
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Head-Mounted Mixed-Reality Technology During Robotic-Assisted Transanal Total Mesorectal Excision

2019

INTRODUCTION Head-mounted mixed-reality technologies may enable advanced intraoperative visualization during visceral surgery. In this technical note, we describe an innovative use of real-time mixed reality during robotic-assisted transanal total mesorectal excision. TECHNIQUE Video signals from the robotic console and video endoscopic transanal approach were displayed on a virtual monitor using a head-up display. The surgeon, assistant, and a surgical trainee used this technique during abdominal and transanal robotic-assisted total mesorectal excision. We evaluated the feasibility and usability of this approach with the use of validated scales. RESULTS The technical feasibility of the rea…

MaleVisceral surgerymedicine.medical_specialtyRobotic assistedComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISIONTransanal approachAdenocarcinoma03 medical and health sciences0302 clinical medicineRobotic Surgical ProceduresHumansMedicineMesenteryMedical physicsAgedTransanal Endoscopic SurgeryProctectomyRectal Neoplasmsbusiness.industryVirtual RealityGastroenterologyTechnical noteUsabilityGeneral MedicineTotal mesorectal excisionMixed realityVisualization030220 oncology & carcinogenesis030211 gastroenterology & hepatologybusinessDiseases of the Colon & Rectum
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