Search results for "visual"

showing 10 items of 7386 documents

CoverageAnalyzer (CAn): A Tool for Inspection of Modification Signatures in RNA Sequencing Profiles

2016

Combination of reverse transcription (RT) and deep sequencing has emerged as a powerful instrument for the detection of RNA modifications, a field that has seen a recent surge in activity because of its importance in gene regulation. Recent studies yielded high-resolution RT signatures of modified ribonucleotides relying on both sequence-dependent mismatch patterns and reverse transcription arrests. Common alignment viewers lack specialized functionality, such as filtering, tailored visualization, image export and differential analysis. Consequently, the community will profit from a platform seamlessly connecting detailed visual inspection of RT signatures and automated screening for modifi…

0301 basic medicineRNA modifications; reverse transcription; reverse transcription (RT) signature; RNA sequencing (RNA-Seq); Next-Generation Sequencing (NGS); candidate screening; alignment viewerNext-Generation Sequencing (NGS)lcsh:QR1-502[ SDV.BBM.BM ] Life Sciences [q-bio]/Biochemistry Molecular Biology/Molecular biologyBiologycomputer.software_genre01 natural sciencesBiochemistryField (computer science)Differential analysisDeep sequencinglcsh:MicrobiologyArticleWorld Wide Web03 medical and health sciencesUser-Computer InterfaceRNA modificationsRNA sequencing (RNA-Seq)[SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry Molecular Biology/Genomics [q-bio.GN]candidate screeningMolecular BiologyComputingMilieux_MISCELLANEOUS010405 organic chemistrySequence Analysis RNAGene Expression ProfilingRNAComputational BiologyHigh-Throughput Nucleotide Sequencing[SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry Molecular Biology/Molecular biologyreverse transcription (RT) signaturereverse transcriptionFile formatalignment viewer0104 chemical sciencesVisualizationVisual inspection030104 developmental biology[ SDV.BBM.GTP ] Life Sciences [q-bio]/Biochemistry Molecular Biology/Genomics [q-bio.GN]Data miningcomputerSoftwareBiomolecules
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RepeatsDB 2.0: improved annotation, classification, search and visualization of repeat protein structures

2017

RepeatsDB 2.0 (URL: http://repeatsdb.bio.unipd.it/) is an update of the database of annotated tandem repeat protein structures. Repeat proteins are a widespread class of non-globular proteins carrying heterogeneous functions involved in several diseases. Here we provide a new version of RepeatsDB with an improved classification schema including high quality annotations for ∼5400 protein structures. RepeatsDB 2.0 features information on start and end positions for the repeat regions and units for all entries. The extensive growth of repeat unit characterization was possible by applying the novel ReUPred annotation method over the entire Protein Data Bank, with data quality is guaranteed by a…

0301 basic medicineRepetitive Sequences Amino Acid[SDV.BC]Life Sciences [q-bio]/Cellular BiologyBiologyBioinformaticsSearch engineAnnotationStructure-Activity Relationship03 medical and health sciences0302 clinical medicineTandem repeatGeneticsAnimalsHumansDatabase IssueDatabases ProteinComputingMilieux_MISCELLANEOUSRepeat unit030304 developmental biology0303 health sciencesInformation retrievalProteinscomputer.file_formatProtein Data BankVisualizationSchema (genetic algorithms)030104 developmental biologyData qualityCorrigendumcomputerSoftware030217 neurology & neurosurgeryNucleic Acids Research
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Peripherin-2 differentially interacts with cone opsins in outer segments of cone photoreceptors

2016

Peripherin-2 is a glycomembrane protein exclusively expressed in the light-sensing compartments of rod and cone photoreceptors designated as outer segments (OS). Mutations in peripherin-2 are associated with degenerative retinal diseases either affecting rod or cone photoreceptors. While peripherin-2 has been extensively studied in rods, there is only little information on its supramolecular organization and function in cones. Recently, we have demonstrated that peripherin-2 interacts with the light detector rhodopsin in OS of rods. It remains unclear, however, if peripherin-2 also binds to cone opsins. Here, using a combination of co-immunoprecipitation analyses, transmission electron micr…

0301 basic medicineRhodopsinOpsingenetic structuresmacromolecular substances030105 genetics & heredityBiologymedicine.disease_causeRetinaMice03 medical and health scienceschemistry.chemical_compoundImmunolabelingMicroscopy Electron TransmissionAntigens NeoplasmFluorescence Resonance Energy TransferGeneticsmedicineAnimalsHumansPeripherin 2Molecular BiologyGenetics (clinical)MutationRetinal DegenerationRetinalGeneral MedicineCone Opsinseye diseases030104 developmental biologyFörster resonance energy transfernervous systemchemistryRhodopsinMutationRetinal Cone Photoreceptor CellsBiophysicsbiology.proteinsense organsProtein BindingVisual phototransductionHuman Molecular Genetics
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Correlation between work impairment, scores of rhinitis severity and asthma using the MASK-air ® App

2020

Background: In allergic rhinitis, a relevant outcome providing information on the effectiveness of interventions is needed. In MASK-air (Mobile Airways Sentinel Network), a visual analogue scale (VAS) for work is used as a relevant outcome. This study aimed to assess the performance of the work VAS work by comparing VAS work with other VAS measurements and symptom-medication scores obtained concurrently. Methods: All consecutive MASK-air users in 23 countries from 1 June 2016 to 31 October 2018 were included (14 189 users; 205 904 days). Geolocalized users self-assessed daily symptom control using the touchscreen functionality on their smart phone to click on VAS scores (ranging from 0 to 1…

0301 basic medicineSYMPTOMSSmart phoneAllergyEscala visual analógicaINNOVATION[SDV]Life Sciences [q-bio]Medical and Health SciencesCorrelationvisual analogue scale0302 clinical medicineQuality of lifeVisual analogue scaleQUALITY-OF-LIFEMàscaresImmunology and AllergyscoreNoseRinitisRhinitisPRODUCTIVITY COSTSasthma; MASK; rhinitis; score; visual analogue scaleScoreExplained variationResponse VariabilityMobile ApplicationsALLERGIC RHINITISrhinitimedicine.anatomical_structureTRIALSRinite1107 Immunology[SDV.IMM]Life Sciences [q-bio]/ImmunologySmartphonemedicine.medical_specialtyMASKVisual analogue scaleMASK study groupImmunologyMACVIA-ARIA03 medical and health sciencesAllergicrhinitismedicineHumansvisual analogue scale.TECHNOLOGYIMMUNOTHERAPYAsmaAsthmabusiness.industryasthma; MASK; rhinitis; score; visual analogue scale; Humans; Smartphone; Asthma; Mobile Applications; Rhinitis; Rhinitis Allergicasthmamedicine.diseaseRhinitis AllergicAsthmaRHINOCONJUNCTIVITIS030104 developmental biology030228 respiratory system3121 General medicine internal medicine and other clinical medicinePhysical therapyClinical Medicinebusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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Effects of in-office bleaching on human enamel and dentin. Morphological and mineral changes

2017

Abstract Background The effects of HP-based products upon dental enamel and dentin are inconclusive. Aim To evaluate changes in micromorphology and composition of calcium (Ca) and phosphate (P) in enamel and dentin after the application of 37.5% hydrogen peroxide (HP) and 35% carbamide peroxide (CP) Methods Crowns of 20 human teeth were divided in two halves. One half was used as control specimen and the other as experimental specimen. The control specimens were kept in artificial saliva, and the experimental specimens were divided into four groups (n = 5 each): group 1 (enamel HP for 45 min); group 2 (dentin HP for 45 min); group 3 (enamel CP for 90 min); and group 4 (dentin CP for 90 min)…

0301 basic medicineSalivaDentistryCarbamide PeroxidePhosphates03 medical and health scienceschemistry.chemical_compoundDogs0302 clinical medicinestomatognathic systemTooth BleachingDentinmedicineAnimalsHumansUreaDental EnamelTooth Bleaching AgentsHydrogen peroxideEnvironmental scanning electron microscopeMineralsMicroscopy ConfocalEnamel paintbusiness.industryDental enamelHydrogen Peroxide030206 dentistryGeneral MedicinePeroxidesstomatognathic diseases030104 developmental biologymedicine.anatomical_structurechemistryvisual_artDentinvisual_art.visual_art_mediumUreaCalciumAnatomyCarbamide peroxidebusinessToothDevelopmental BiologyAnnals of Anatomy - Anatomischer Anzeiger
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Evaluation of the erosive capacity of children’s beverages on primary teeth enamel: An in vitro study

2018

Background The consumption of acidified beverages, associated with lower mineralization of primary enamel, is the ideal combination for the development and progression of dental erosion. The objective of this study is to analyze the erosive capacity and the surface roughness of primary teeth enamel after exposure to three different brands of grape juices. Material and Methods Forty enamel blocks of primary teeth were obtained, attened and polished. They were submitted to initial surface roughness analysis (baseline), and randomly assigned into four groups (n = 10): NAT: natural grape juice (Campo Largo); IND: industrialized grape juice (Dell Vale Kapo); SOY: soy-based grape juice (Ades); an…

0301 basic medicineSalivaEnamel paintChemistryDental enamelfungiTitratable acid030206 dentistry:CIENCIAS MÉDICAS [UNESCO]Mineralization (biology)stomatognathic diseases03 medical and health sciences030104 developmental biology0302 clinical medicinestomatognathic systemGrape juicesvisual_artUNESCO::CIENCIAS MÉDICASSurface roughnessvisual_art.visual_art_mediumIn vitro studyFood scienceGeneral DentistryJournal of Clinical and Experimental Dentistry
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Anti-erosive effect of calcium carbonate suspensions

2018

Background This study aimed to investigate the ability of different concentrations of calcium carbonate (CaCO3) suspensions to control enamel surface loss. Material and methods Seventy-five enamel slabs were embedded, ground and polished in a pneumatic grinder-polisher machine. Reference areas were created with UPVC tape and the specimens were randomly allocated into five groups (n = 15) for exposure to hydrochloric acid solution to simulate gastric juice (0.01 M, pH 2) for 2 minutes. The samples were then exposed to suspensions containing 0.0001, 0.001, 0.01 or 0.1 mmol/L CaCO3 for 1 minute. Artificial saliva was used as control. The samples were subjected to a total of five erosive cycles…

0301 basic medicineSalivaEnamel paintChemistryOptical profilometryResearch030106 microbiologyHydrochloric acid030206 dentistry:CIENCIAS MÉDICAS [UNESCO]Community and Preventive DentistrySurface lossSuspension (chemistry)03 medical and health scienceschemistry.chemical_compound0302 clinical medicineCalcium carbonatevisual_artUNESCO::CIENCIAS MÉDICASvisual_art.visual_art_mediumGastric acidGeneral DentistryNuclear chemistry
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Quantitative and Qualitative in vivo Analysis of Metal Residuals in the Saliva of Subjects with and without Fixed Orthodontic Appliances

2020

Aim of the Work: The aim of this work was to evaluate Ni e Cr ions in the saliva of subjects with and without fixed orthodontic appliances. Materials and Methods: This was a prospective, non-randomized study of 100 patients, so selected: 50 have undergone fixed orthodontic appliance at least from 24 months; others 50 subjects as control-group, without any fixed and/or removable orthodontic appliance It was conducted according to the Declaration of the World Medical Association of Helsinki. The two selected groups were compatible for age, sex, absence of restoration in amalgam or other metals in the oral cavity. The saliva of all the subjects was collected with standardized sterile methods. …

0301 basic medicineSalivaMaterials scienceMetal ions in aqueous solutionfungiMetallurgytechnology industry and agriculture030206 dentistryGeneral MedicineBiocompatible materialCorrosionMetal03 medical and health sciences030104 developmental biology0302 clinical medicineNickel titaniumFixed Orthodontic Appliancevisual_artGalvanic cellvisual_art.visual_art_mediumNickel ionsAtomic Absorption SpectrophotometryMetal IonSaliva
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The effect of aspartame and pH changes on the erosive potential of cola drinks in bovine enamel: an in vitro study

2018

Background The aim of this study was to clarify the mechanism behind the different erosive potential of regular and light cola drinks: pH difference and/or aspartame presence. Material and methods Sixty bovine enamel blocks were randomly divided into 5 groups: RC - regular cola, RCpH - addition of base to increase regular cola pH, RCAS - addition of aspartame to regular cola, LC - light cola, and LCpH - addition of acid to decrease light cola pH. Two-thirds of the blocks surface was coated with nail varnish for reference. The samples were daily subjected to four erosive challenges for 2 minutes. Between the erosive challenges (2h) and overnight the samples were maintained in artificial sali…

0301 basic medicineSalivaOLIGOPEPTÍDEOSPh changesCola (plant)03 medical and health scienceschemistry.chemical_compound0302 clinical medicineIn vitro studyBovine enamelFood scienceGeneral DentistryEnamel paintAspartamebiologyResearch030206 dentistrybiology.organism_classification:CIENCIAS MÉDICAS [UNESCO]Community and Preventive DentistrySurface losschemistryvisual_artUNESCO::CIENCIAS MÉDICASvisual_art.visual_art_medium030101 anatomy & morphology
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Demo

2017

We present an innovative smartphone-centric tracking system for indoor and outdoor environments, based on the joint utilization of dead-reckoning and computer vision (CV) techniques. The system is explicitly designed for visually impaired people (although it could be easily generalized to other users) and it is built under the assumption that special reference signals, such as painted lines, colored tapes or tactile pavings are deployed in the environment for guiding visually impaired users along pre-defined paths. Thanks to highly optimized software, we are able to execute the CV and sensor-fusion algorithms in run-time on low power hardware such as a normal smartphone, precisely tracking …

0301 basic medicineSensor FusionComputer scienceVisually impairedbusiness.industry05 social sciencesTracking systemSensor fusionNavigation03 medical and health sciencesComputer Networks and Communication030104 developmental biologySoftwareColoredHardware and ArchitectureLocalization0501 psychology and cognitive sciencesComputer visionArtificial intelligenceVisually ImpairedbusinessJoint (audio engineering)Software050107 human factorsProceedings of the 23rd Annual International Conference on Mobile Computing and Networking
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