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Effect of endothelial cell heterogeneity on nanoparticle uptake.
2020
Endothelial cells exhibit distinct properties in morphology and functions in different organs that can be exploited for nanomedicine targeting. In this work, endothelial cells from different organs, i.e. brain, lung, liver, and kidney, were exposed to plain, carboxylated, and amino-modified silica. As expected, different protein coronas were formed on the different nanoparticle types and these changed when foetal bovine serum (FBS) or human serum were used. Uptake efficiencies differed strongly in the different endothelia, confirming that the cells retained some of their organ-specific differences. However, all endothelia showed higher uptake for the amino-modified silica in FBS, but, inter…
Fast comparison of DNA sequences by oligonucleotide profiling
2008
Provisional abstact and full-text PDF files correspond to the article as it appeared upon acceptance. Fully formatted PDF and final abstract will be made available soon.
Antecedentes de las consultas de boca-oído online sobre hoteles
2017
Las consultas online sobre productos y servicios antes de la compra han recibido menor atención en la literatura que la generación de comentarios después de la experiencia. Nuestro trabajo aborda, por tanto, el estudio de la conducta de boca-oído online desde la perspectiva del receptor. El objetivo es investigar las variables que contribuyen en la adopción de boca-oído online para tomar la decisión de elección de un hotel. Para ello, se analiza la cadena de relaciones “motivaciones→intención de consultar→volumen→adopción”, considerando tres tipos de motivaciones: conveniencia, riesgo y sociales. Con una muestra de 393 huéspedes de hoteles de 3, 4 y 5 estrellas y a partir de un modelo de ec…
Coherence between brain activation and speech envelope at word and sentence levels showed age-related differences in low frequency bands
2021
Abstract Speech perception is dynamic and shows changes across development. In parallel, functional differences in brain development over time have been well documented and these differences may interact with changes in speech perception during infancy and childhood. Further, there is evidence that the two hemispheres contribute unequally to speech segmentation at the sentence and phonemic levels. To disentangle those contributions, we studied the cortical tracking of various sized units of speech that are crucial for spoken language processing in children (4.7–9.3 years old, N = 34) and adults (N = 19). We measured participants’ magnetoencephalogram (MEG) responses to syllables, words, and…
Production et circulation des épées à poignée métallique de l'âge du Bronze en Europe occidentale
2022
Several regional syntheses have been published on Bronze Age solid-hilted swords, but none for France and the Benelux countries. This dissertation aims first at filling this gap by listing the swords from this region. By adding data from these pre-existing studies, it is possible to study the distribution of solid-hilted swords on a European scale. The building of an inventory is an essential condition to study the diffusion of these weapons over long distances. This must come along with models to characterise the organisation of the swords production and the ways they spread out. It requires us to question the status of the craftsmen, their organisation and their location. One of the first…
L’épée, arme et symbole. Le point de vue technique sur les fonctions des épées à poignée métallique de l’âge du Bronze
2018
The sword, which was invented during Bronze Age, is certainly the ultimate weapon, associated to war and warriors, designed to fight during combats. However, because of its technical complexity, its ostentatious aspect, especially when it is equipped with a bronze hilt, or its strong individualization for example through ornaments, swords can also be considered as symbols. This symbol can be connected to an individual, a social position, a community or to another concept we cannot precisely understand. Of course, material and immaterial aspects do not always exclude each other, and a single object can be used for both. However, a first inspection of these weapons shows that some of them cou…
L’épée à poignée métallique de Niffer (Haut-Rhin) : un exemple de production occidentale au Bronze moyen
2018
National audience
Were Bronze Age metalworkers skilled?: Perspectives from the study of the making of Bronze Age swords
2019
International audience; Beyond the provocation of the title, the question of ancient metalworkers’ skills, that has been recently discussed by Maikel Kuijpers for Bronze Age axes, makes perfect sense concerning Bronze Age swords, especially when equipped with a metallic hilt. These weapons are indeed almost always described as masterpieces of metalwork made by skilled and specialized craftsmen. This does not take into account the breakthroughs made since the 1960s in the study of the fabrication techniques of bronze artefacts. Even if it is true that most Bronze Age swords are looking flawless on the surface, imaging techniques such as X-ray or CT-scan enable archaeologists to have a glimps…
The true and the fake: archaeometric investigations on two Bronze Age solid-hilted swords from East Flanders (Belgium)
2020
International audience
Réparations et appropriation. Quelques considérations sur des épées personnalisées du Bronze final
2019
International audience; Repair is an action aiming at giving an object is functionality back. This is of course an economic process: if it is not possible to use an artefact for the purpose it was designed for, for example if it is flawed or worn out, then it needs to be smelted or repaired. But the cultural aspect of functionality shall not be forgotten. In Bronze Age societies, all items crafted had to look a certain way, and not another, varying according to the considered regions or time periods.Bronze Age swords are no exception to the rule. The shape of the hilt is particularly standardized, contributing to the visual identity of the weapon. For example, at the end of the Bronze Age (…