Search results for "work"

showing 10 items of 14511 documents

Metabolic Reprogramming of Innate Immune Cells as a Possible Source of New Therapeutic Approaches in Autoimmunity.

2022

Immune cells undergo different metabolic pathways or immunometabolisms to interact with various antigens. Immunometabolism links immunological and metabolic processes and is critical for innate and adaptive immunity. Although metabolic reprogramming is necessary for cell differentiation and proliferation, it may mediate the imbalance of immune homeostasis, leading to the pathogenesis and development of some diseases, such as autoimmune diseases. Here, we discuss the effects of metabolic changes in autoimmune diseases, exerted by the leading actors of innate immunity, and their role in autoimmunity pathogenesis, suggesting many immunotherapeutic approaches.

therapyoxidative phosphorylationchronic inflammatory diseaseAutoimmunityGeneral MedicineglycolysisAdaptive Immunityimmune responseImmunity InnateAutoimmune Diseasesmetabolic pathwaysHumansinnate immunityMetabolic Networks and PathwaysCells
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El edificio gremial de los abaixadors o tundidores, en Valencia

2020

In the ?barri del mercat?, in the city of Valencia and very close to its Lonja, there is a building complex which is the object of this study. The research, carried out from the simple field of toponymy, to the constructive analysis, lead us to suppose that it is the building of the Valencian trade union of cloth-shearers. It can be seen how the building now camouflaged by other subsequent interventions, corresponds to a type that cannot be related to those usually built in the city of Valencia. Its origins clearly from the Valencian self-governing period splendor, its dimensions and the finishes used in its construction seem to refer to a medieval workshop. A structure of great importance …

there is a building complex which is the object of this study. The researchUNESCO::CIENCIAS DE LAS ARTES Y LAS LETRASin the city of Valencia and very close to its Lonjahave come to confirm this hypothesis. This article offers unpublished graphic documentationits dimensions and the finishes used in its construction seem to refer to a medieval workshop. A structure of great importance has been recognized that jointly affects the different properties today. This together with other circumstances of their own as necessary to exercise the office of abaxadoren Valencia Gómez Gilwhich gives an account of the current status of the property and suggests a reconstructive hypothesisRamón0211-5808 9678 Archivo de arte valenciano 564145 2020 101 7707981 El edificio gremial de los abaixadors o tundidoresAntonioAmanda In the ?barri del mercat?existing in the buildingcorresponds to a type that cannot be related to those usually built in the city of Valencia. Its origins clearly from the Valencian self-governing period splendor:CIENCIAS DE LAS ARTES Y LAS LETRAS [UNESCO]both in plan and in volume. 127 145carried out from the simple field of toponymyto the constructive analysislead us to suppose that it is the building of the Valencian trade union of cloth-shearers. It can be seen how the building now camouflaged by other subsequent interventions
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Thermal anomalies detection in a photovoltaic plant using artificial intelligence: Italy case studies

2021

This paper proposes the application of artificial intelligence techniques for the identification of thermal anomalies that occur in a photovoltaic system due to malfunctions or faults, with the aim to limit the energy production losses by detecting faults at an early stage. The proposed approach is based on a Thermographic Non-Destructive Test conducted with Unmanned Aerial Vehicles equipped with a thermal imaging camera, which allows the detection of abnormal operating conditions without interrupting the normal operation of the PV system rapidly and cost-effectively. The thermographic images and videos are automatically inspected using a Convolutional Neural Network, developed by an open-s…

thermal anomaliesbusiness.industryComputer sciencePhotovoltaic systemSettore ING-IND/32 - Convertitori Macchine E Azionamenti Elettriciartificial intelligenceConvolutional neural networkReduction (complexity)Identification (information)photovoltaic systeminfrared thermographyLimit (music)ThermalAutomatic detectionStage (hydrology)Artificial intelligencebusinessEnergy (signal processing)2021 IEEE International Conference on Environment and Electrical Engineering and 2021 IEEE Industrial and Commercial Power Systems Europe (EEEIC / I&CPS Europe)
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The thermal performances of historic masonry: In-situ measurements of thermal conductance on calcarenite stone walls in Palermo

2018

Abstract Rich literature explores materials and construction techniques of historic buildings, but limited information is available about the thermal and hygrometric features of their envelope. Nevertheless, accurate hygrothermal data are essential for identifying effective energy upgrade measures, which must be compatible with the conservation of the architectural heritage. In order to fill this gap, it is necessary to refer to local contexts, where the variety of historic buildings is limited and their material and construction features are comparable. This paper focuses on historic masonry walls and discusses the results of twenty in-situ measurements of thermal conductance, performed al…

thermal conductance020209 energy0211 other engineering and technologiestrasmittanza termicaSettore ICAR/10 - Architettura Tecnicaconduttanza termicahistoric masonry02 engineering and technologyPalermoedifici storicihistoric buildingThermal conductivityEffective energyArchitectural heritagecalcarenite021105 building & constructionThermalefficienza energetica0202 electrical engineering electronic engineering information engineeringKnowledge frameworkGeotechnical engineeringarchitettura storicaElectrical and Electronic Engineeringenergy efficiencyCivil and Structural Engineeringthermal transmittancebusiness.industryMechanical EngineeringBuilding and ConstructionMasonrycalcarenite stone wallCalcareniteThermal transmittancebusinessGeologyEnergy and Buildings
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Interactive Tools for the Preservation, Dissemination and Study of Silk Heritage—An Introduction to the SILKNOW Project

2018

Silk was a major factor for progress in Europe, mostly along the Western Silk Road’s network of production and market centers. The silk trade also allowed for the exchange of ideas and innovations, having impacts at economic, technical, functional, cultural and symbolic levels. However, silk has today become a seriously endangered heritage. Although many European specialized museums are devoted to its preservation, they usually lack the size and resources to take advantage of state-of-the-art digital technologies. The aim of this paper is twofold; firstly, we introduce SILKNOW, an interdisciplinary project that has been recently funded by the H2020 Programme of the European Union in order t…

thesaurusArchitectural engineeringComputer Networks and CommunicationsNeuroscience (miscellaneous)silk heritage02 engineering and technologyinteractive toolslcsh:Technology01 natural sciencesOrder (exchange)0202 electrical engineering electronic engineering information engineeringmedia_common.cataloged_instanceEuropean unionlcsh:SciencePatrimoni culturalmedia_commonlcsh:T010401 analytical chemistry020207 software engineering0104 chemical sciencesComputer Science ApplicationsHuman-Computer InteractionSILKvirtuallcsh:QBusinessMultimodal Technologies and Interaction
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The (im)possible success of disadvantaged students. Reflections on education, migration and social change

2019

The paper focuses on the ?unexpected pathways? of successful students with an immigrant background: these biographical routes, that seems socially impossible, raise theoretical issues around the individual-society, actor-structure relationship. Disadvantaged students who succeed represent a sociological challenge in the attempt to understand atypical situations and to identify the institutional processes and the structural opportunities that facilitate them, reducing ethnic inequalities in education. This framework is the starting point of the Su.Per. project (Success in educational pathways of students with immigrant background), based on the collection of written autobiographies of 65 imm…

these biographical routes [Mariagrazia The paper focuses on the ?unexpected pathways? of successful students with an immigrant background]relación educación-migración-sociedadmigration and social change Santagatithat seems socially impossibleattending upper secondary education in Northern Italy. The biographical approach allows to deepen the social change that derives from the positive impact of immigration on education. Within this interpretative perspectiveéxito escolar 51 57raise theoretical issues around the individual-societyactor-structure relationship. Disadvantaged students who succeed represent a sociological challenge in the attempt to understand atypical situations and to identify the institutional processes and the structural opportunities that facilitate thembut also giving voice and supports to disadvantaged studentsschool successSettore SPS/08 - SOCIOLOGIA DEI PROCESSI CULTURALI E COMUNICATIVIthat considers possible the educational success of immigrant studentsimmigrant students:SOCIOLOGÍA [UNESCO]students of immigrant originreducing ethnic inequalities in education. This framework is the starting point of the Su.Per. project (Success in educational pathways of students with immigrant background)the article underlines the contribute of the Su.Per. project to a new ?definition of the situation?and introducing them to a field of unforeseen possibilities. education-migration-society relationship1137-7038 8537 Arxius de sociologia 525290 2019 40 7038139 The (im)possible success of disadvantaged students. Reflections on educationdrawing new narratives and discourses on inequalitieseducational successUNESCO::SOCIOLOGÍAMariagrazia The paper focuses on the ?unexpected pathways? of successful students with an immigrant background: these biographical routesbased on the collection of written autobiographies of 65 immigrant studentsalumnos de origen inmigrante
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The new face of university–business cooperation in Finland

2016

This paper analyses the development of university-business cooperation (UBC) in Finland in the context of the University Reform Act of 2009, drawing on the experience of four universities: Aalto University, University of Jyvaskyla, University of Turku, and Lappeenranta University of Technology. Six UBC dimensions are examined: institutional context, stakeholders, motivations, facilitators/inhibitors, benefits, and drawbacks. We find that UBC, while a relatively recent process, is growing fast in dynamic local innovation and entrepreneurship ecosystems. The University Act of 2009 had an uneven effect on the six UBC dimensions, with the most visible impact being manifested on motivations. Aal…

third missionPublic AdministrationGeography Planning and DevelopmentcooperationFace (sociological concept)Management Monitoring Policy and Law050905 science studiesPolitical science0502 economics and businessuniversity sectorstakeholderbusinessta512Finlandentrepreneurship educationeducationtechnology transferbusiness.industry05 social sciencesStakeholderentrepreneurinstitutional frameworkPublic relationsinnovationTechnology transferentrepreneurial university0509 other social sciencesbusiness050203 business & managementuniversitiesScience and Public Policy
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Reducing the Time to Detect Cyber Attacks : Combining Attack Simulation With Detection Logic

2021

Cyber attacks have become harder to detect, causing the average detection time of a successful data breach to be over six months and typically costing the target organization nearly four million dollars. The attacks are becoming more sophisticated and targeted, leaving unprepared environments easy prey for the attackers. Organizations with working antivirus systems and firewalls may be surprised when they discover their network has been encrypted by a ransomware operator. This raises a serious question, how did the attacks go undetected? The conducted research focuses on the most common pitfalls regarding late or even non-existent detection by defining the root cause behind the failed detec…

threat detectionorganisaatiotTK5101-6720threat analysiscyber defensetietotekniikkacybersecurity frameworktestauscyber attack simulationTelecommunicationsimulointisoctietoturvakyberturvallisuusverkkohyökkäyksetexploitationpalomuurit (tietoturva)
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ACTO II / ACT II Mujeres / Women ¿Es gay la música de Chopin? Aspectos de la recepción de la música de Chopin en el siglo XIX

2021

Considering that it is difficult, if not impossible, for an analysis of Chopin?s music to unmask some aspects of his private life (such as an alleged sexual and affective attraction for individuals of his own sex), we can however argue that, throughout the 19th century, a connection was established between his work and a ?feminine universe.? That connection might have had implications in the way in which the feminized image of its author was constructed. The analysis of certain aesthetic and stylistic traits of Chopin?s music can help understand the causes of that perception.

throughout the 19th centuryUNESCO::CIENCIAS DE LAS ARTES Y LAS LETRASrevista de investigación musical: territorios para el arte 590908 2021 7 8182078 ACTO II / ACT II Mujeres / Women ¿Es gay la música de Chopin? Aspectos de la recepción de la música de Chopin en el siglo XIX Alboterritorios para el arte 590908 2021 7 8182078 ACTO II / ACT II Mujeres / Women ¿Es gay la música de Chopin? Aspectos de la recepción de la música de Chopin en el siglo XIX Albo [revista de investigación musical]:CIENCIAS DE LAS ARTES Y LAS LETRAS [UNESCO]Francisco Javier Considering that it is difficultif not impossiblea connection was established between his work and a ?feminine universe.? That connection might have had implications in the way in which the feminized image of its author was constructed. The analysis of certain aesthetic and stylistic traits of Chopin?s music can help understand the causes of that perception. 489 5062386-8260 13268 Itamarfor an analysis of Chopin?s music to unmask some aspects of his private life (such as an alleged sexual and affective attraction for individuals of his own sex)we can however argue that
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Overview of Power Electronic Switches: A Summary of the Past, State-of-the-Art and Illumination of the Future.

2020

As the need for green and effective utilization of energy continues to grow, the advancements in the energy and power electronics industry are constantly driven by this need, as both industries are intertwined for obvious reasons. The developments in the power electronics industry has over the years hinged on the progress of the semiconductor device industry. The semiconductor device industry could be said to be on the edge of a turn into a new era, a paradigm shift from the conventional silicon devices to the wide band gap semiconductor technologies. While a lot of work is being done in research and manufacturing sectors, it is important to look back at the past, evaluate the current progr…

thyristorsEngineeringinsulated gate bipolar transistorslcsh:Mechanical engineering and machinery02 engineering and technologyReviewbipolar transistors01 natural sciencesElectronic switchpower semiconductor devicesPower electronics0103 physical sciences0202 electrical engineering electronic engineering information engineeringPower semiconductor devicelcsh:TJ1-1570Electrical and Electronic Engineering010302 applied physicsbusiness.industrypower semiconductor switchesMechanical Engineering020208 electrical & electronic engineeringThyristorSemiconductor deviceVDP::Teknologi: 500Work (electrical)Control and Systems EngineeringParadigm shiftState (computer science)businessTelecommunicationspower transistorsMicromachines
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