Search results for "wound-healing"
showing 2 items of 2 documents
C1q as a novel player in angiogenesis with therapeutic implication in wound healing
2014
We have previously shown that C1q is expressed on endothelial cells (ECs) of newly formed decidual tissue. Here we demonstrate that C1q is deposited in wound-healing skin in the absence of C4 and C3 and that C1q mRNA is locally expressed as revealed by real-time PCR and in situ hybridization. C1q was found to induce permeability of the EC monolayer, to stimulate EC proliferation and migration, and to promote tube formation and sprouting of new vessels in a rat aortic ring assay. Using a murine model of wound healing we observed that vessel formation was defective in C1qa(-/-) mice and was restored to normal after local application of C1q. The mean vessel density of wound-healing tissue and …
Organizacja opieki nad pacjentami z ranami przewlekłymi
2008
W pracy omówiono problemy związane z organizacją leczenia ran przewlekłych. Model systemu opieki nad chorym z przewlekłą raną powinien opierać się na trzech filarach: lokalnej poradni leczenia ran, specjalistycznych centrach leczenia ran pełniących rolę ośrodka referencyjnego oraz na klubach pacjentów, w których można rozwiązać problemy psychospołeczne.