Search results for "wt"
showing 10 items of 5424 documents
In vivo and in vitro sensitivity of blastic plasmacytoid dendritic cell neoplasm to SL-401, an interleukin-3 receptor targeted biologic agent.
2015
International audience; Blastic plasmacytoid dendritic cell neoplasm is an aggressive malignancy derived from plasmacytoid dendritic cells. There is currently no accepted standard of care for treating this neoplasm, and therapeutic strategies have never been prospectively evaluated. Since blastic plasmacytoid dendritic cell neoplasm cells express high levels of interleukin-3 receptor α chain (IL3-Rα or CD123), antitumor effects of the interleukin-3 receptor-targeted drug SL-401 against blastic plasmacytoid dendritic cell neoplasm were evaluated in vitro and in vivo. The cytotoxicity of SL-401 was assessed in patient-derived blastic plasmacytoid dendritic cell neoplasm cell lines (CAL-1 and …
Effects of biomass, age and functional traits on regrowth of arable weeds after cutting
2008
Conference: 24th German Conference on Weed Biology and Weed ControlLocation: Stuttgart Hohenheim, GERMANYDate: MAR 04-06, 2008; International audience; In sown field margin stripes or pluriannual forage crops, arable weeds are exposed to high competition and regular mowing or hay cutting, to which they may react very differently. A greenhouse experiment permitted to understand some key factors shaping the ability of common arable weeds and forage crops to grow after such cuttings. Even without competition, cutting shoots at 5cm height reduced biomass production of all 10 species studied, but 6 annual broadleaf weeds were much more affected than 2 perennial forage crops (Dactylis, Medicago) …
Identification of Traits Implicated in the Rhizosphere Competence of Fluorescent Pseudomonads: Description of a Strategy Based on Population and Mode…
2009
E-book; International audience; The lack of consistency of the beneficial effects of inoculated fluorescent pseudomonads has often been related to their bad survival in the rhizosphere. In this review, we describe the strategy followed over the last decade to study traits involved in the rhizosphere competence of these bacteria. The diversity of indigenous populations associated with plant roots was first compared to that of populations associated with uncultivated soils in order to identify traits that discriminate these populations. The involvement of these bacterial traits in the rhizosphere competence was then assessed by comparing the competitiveness of a wild-type strain to that of mu…
Methods for studying root colonization by introduced beneficial bacteria
2003
e-Book; Some free-living rhizobacteria are considered as potential biocontrol and plant growth-promoting agents. Successful application of beneficial bacteria as microbial inoculants requires their presence and activity at the appropriate level, but even more, at the right time and place. Various markers are described in the literature to differentiate introduced bacteria from indigenous microflora and to visualize them. These markers are presented together with the methods currently applied to quantify bacterial densities and to characterize the distribution of introduced bacteria. The methods to quantify bacterial densities are either based on bacterial cultivation or not. Different types…
Role of the small heat shock protein alphaB-crystallin in pulmonary fibrosis and its implication in the signaling pathway of the Transforming Growth …
2013
Idiopathic pulmonary fibrosis (IPF) has no effective current treatment. It is characterized by a sub-pleural onset and the presence of myofibroblasts, responsible for the excessive extracellular matrix synthesis. Transforming Growth Factor (TGF)-β1 is considered as the major profibrotic cytokine. Its signaling pathway occurs through the Smads proteins, including Smad4. TGF-β1 allows the differentiation of lung fibroblasts and epithelial and mesothelial cells into myofibroblasts. AB-crystallin is a small heat shock protein overexpressed in liver, renal and vascular fibrosis and can be induced by TGF-β1. In this study, we assessed the role of αB-crystallin in pleural and pulmonary fibrosis. W…
Free-living plant-beneficial microorganisms and soil quality.
2005
CABI Publishing, Wallingford Oxon, UK,
Involvement of communication systems during the sessile growth of Listeria monocytogenes
2007
International audience
Digital tools for a biomass prediction from a plant-growth model. Application to a weed control in wheat crop
2019
International audience; Weed control is essential for crop quality and yield. Usually, the main factors affectingdecision-making of farmers in weeding are based on the presence of certain weedvarieties and their density (plants/m2). However, the weed management at the scale ofthe crop cycle refers to other competition indicators, more reliable, such as plantbiomass or leaf area index (LAI). Classically, plant biomass measurements are obtainedby a destructive method of sampling, time consuming and it turns out to be unworkablein practice for farmers. This project proposes to study an innovative method of biomassevaluation which is based on the acquisition of plot images to determine the leaf…
Growth and development of Ambrosia artemisiifolia L. under different trophic conditions
2014
Ambrosia artemisiifolia L. (common ragweed) is an annual weed regarded as an invasive plant in France. This species can be found in a large range of soil types with regard to texture, pH or nutrient contents. Furthermore, its tolerance to different forms of stress increases its spread potential. This work was undertaken to evaluate the development and growth of common ragweed under different trophic conditions in a common garden. Three cohorts of 15 plants per treatments were sown in spring 2013 and the effects of nitrogen and irrigation were compared on each sowing dates. During the first weeks, vegetative appearance is strongly linked with the sum of temperature. For the first cohort, the…
Characterization of the role of flagellin in the innate immunity triggered by the endophytic pgpr burkholderia phytofirmans in arabidopsis and grapev…
2014
International audience