Search results for "wt"

showing 10 items of 5424 documents

Thiazole Analogues of the Marine Alkaloid Nortopsentin as Inhibitors of Bacterial Biofilm Formation

2020

Anti-virulence strategy is currently considered a promising approach to overcome the global threat of the antibiotic resistance. Among different bacterial virulence factors, the biofilm formation is recognized as one of the most relevant. Considering the high and growing percentage of multi-drug resistant infections that are biofilm-mediated, new therapeutic agents capable of counteracting the formation of biofilms are urgently required. In this scenario, a new series of 18 thiazole derivatives was efficiently synthesized and evaluated for its ability to inhibit biofilm formation against the Gram-positive bacterial reference strains Staphylococcus aureus ATCC 25923 and S. aureus ATCC 6538 a…

thiazole derivativeAquatic OrganismsStaphylococcus aureusIndolesantibiotic resistanceSettore BIO/05 - ZoologiaPharmaceutical ScienceMicrobial Sensitivity TestsBacterial growthSettore BIO/19 - Microbiologia Generalemedicine.disease_cause01 natural sciencesArticlenortopsentinAnalytical ChemistryMicrobiologylcsh:QD241-441Inhibitory Concentration 50chemistry.chemical_compoundAlkaloidsAntibiotic resistancelcsh:Organic chemistryDrug DiscoverymedicinePhysical and Theoretical ChemistryThiazoleStrain (chemistry)010405 organic chemistryPseudomonas aeruginosamarine alkaloids analoguesAlkaloidOrganic ChemistryImidazolesBiofilmantibiofilm agentsSettore CHIM/08 - Chimica Farmaceuticamarine alkaloids analogueantibiofilm agent0104 chemical sciencesThiazoles010404 medicinal & biomolecular chemistrychemistryChemistry (miscellaneous)Staphylococcus aureusBiofilmsPseudomonas aeruginosathiazole derivativesMolecular MedicineMolecules
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Esseitä Humen luonnonfilosofiasta

2016

Väitöstilaisuuden lektio pidetty 17.9.2016, klo 12 Ruusupuiston Helena-salissa, Jyväskylän yliopistossa.

tieteenfilosofiakokeellisuuslektiotNewton Isaacaika ja avaruustodellisuusnaturalismi (filosofia)kausaliteettiEinstein AlbertluonnonlaitempirismiLektiotHume DavidluonnonfilosofiaAjatus
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Essays concerning Hume's natural philosophy

2016

The subject of this essay-based dissertation is Hume’s natural philosophy. The dissertation consists of four separate essays and an introduction. These essays do not only treat Hume’s views on the topic of natural philosophy, but his views are placed into a broader context of history of philosophy and science, physics in particular. The introductory section outlines the historical context, shows how the individual essays are connected, expounds what kind of research methodology has been used, and encapsulates the research contributions of the essays. The first essay treats Newton’s experimentalist methodology in gravity research and its relation to Hume’s causal philosophy. It is argued tha…

tieteenhistoriatieteenfilosofiakokeellisuusNewton IsaacexperimentalismHume's Forkcausationavaruusspace and timekausaliteettiEinstein AlbertaikaluonnonlaitväittämätHume Davidlaws of natureluonnonfilosofiaHumen haarukkahistory of philosophy and science
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Information, Communications and Media Technologies for Sustainability: Constructing Data-Driven Policy Narratives

2021

This paper introduces the idea of data-driven narratives to examine how the use of information, communications, and media technologies (ICMTs) impacts the sustainable growth of economies. While ICMTs have regularly been advocated as a policy tool for growth and development, there is a research gap in empirical studies validating how such policies may be effective. This analysis is based on historical panel data from 39 economies across the developed North (19) and developing South (20). The industry-standard Cross-Industry Standard Process for Data Mining (CRISP-DM) methodology was applied to construct narratives that weave extant theories with empirical data. The art of developing data-dri…

tieto- ja viestintätekniikkalcsh:TJ807-830Geography Planning and Developmenttulotasolcsh:Renewable energy sourcestaloudellinen kehitysCRISP-DM methodologyManagement Monitoring Policy and LawtalouskasvuEmpirical researchPolitical scienceNarrativedata analytics and modelinglcsh:Environmental scienceslcsh:GE1-350Sustainable developmentkestävä kehitysRenewable Energy Sustainability and the Environmentbusiness.industrylcsh:Environmental effects of industries and plantstaloudellinen kestävyysanalyysimenetelmätPublic relationssustainable development goalskansainvälinen vertailuCross-Industry Standard Process for Data Mining (CRISP-DM)tavoitteetlcsh:TD194-195kehitysmaatIT for developmentdataSustainabilityIntermediationtiedonlouhintabusinessSustainable growth rateConstruct (philosophy)Panel dataSustainability
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Qualitative analysis of housing demand using Google trends data

2019

Big data analytics often refer to the breakdown of huge amounts of data into a more readable and useful format. This study utilises Google Trends big data as a proxy for an analysis of housing demand. We employ a qualitative method (fuzzy set/Qualitative Comparative Analysis, fsQCA), instead of a quantitative method, for our estimate and forecast. The empirical results show that fsQCA successfully forecasts seasonal time series, even though the dataset is small in size. Our findings fill the gap in the qualitative and time series forecasting literature, and the forecasting procedure herein also offers a good standard for industry.

time series modelshousing demandEconomics and Econometricsbusiness.industryComputer scienceSèries temporals AnàlisiBig datalcsh:Regional economics. Space in economicsData sciencelcsh:HD72-88lcsh:HT388Proxy (climate)lcsh:Economic growth development planningQualitative analysisTime series models; qualitative forecasting; housing demandbusinessqualitative forecastingEconomic Research-Ekonomska Istraživanja
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Honey Bee Pollen in Meagre (Argyrosomus regius) Juvenile Diets: Effects on Growth, Diet Digestibility, Intestinal Traits, and Biochemical Markers Rel…

2020

This research aimed to evaluate the effects of the inclusion of honey bee pollen (HBP) in meagre (Argyrosoumus regius) juveniles&rsquo

total serum proteingrowth trialtrace elementsArgyrosomus regiusmedicine.disease_causemeagre honey bee pollen growth trial digestibility trial TNF-α HSP70 intestinal immunohistochemistry toxic elements trace elements total serum proteinArticleintestinal immunohistochemistry03 medical and health sciencesAnimal sciencePredatory fishIntestinal mucosaSettore AGR/20 - ZoocolturePollenlcsh:Zoologymedicinelcsh:QL1-991toxic elementKeywords: meagreDigestibility trial; Growth trial; Honey bee pollen; HSP70; Intestinal immunohistochemistry; Meagre; TNF-α; Total serum protein; Toxic elements; Trace elementsHSP70030304 developmental biology2. Zero hungertoxic elements0303 health sciencesLamina proprialcsh:Veterinary medicineGeneral Veterinarybiologydigestibility trialfood and beveragestrace elementHistology04 agricultural and veterinary sciencesHoney beebiology.organism_classificationmeagre3. Good healthmedicine.anatomical_structureBee pollenTNF-α040102 fisherieslcsh:SF600-11000401 agriculture forestry and fisheriesAnimal Science and Zoologyhoney bee pollenAnimals
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Relationship of transforming growth factor-beta1 with tumor necrosis factor-alpha and endothelial activation in patients with stable renal transplant…

2008

transforming growth factor-beta tumor necrosis factor-alpha endothelial activation renal transplantation
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Tumor-derived exosomes as factors that promote metastatic niche formation: evaluation of the effects induced by colon cancer derived exosomes on func…

2023

transforming growth factor‑β1 (TGFβ1)colorectal cancer-derived small extracellular vesicleshepatocyteliver metastasis.
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Las Leyes de Newton de la mecánica: Una revisión histórica y sus implicaciones en los textos de enseñanza

2013

Este trabajo destaca la importancia de una presentación coherente y actualizada de la dinámica clásica como un factor clave para su aprendizaje. La primera parte de este trabajo contiene un análisis histórico de los aspectos críticos de las leyes de la dinámica clásica que muestra sus ambigüedades y sus posibles interpretaciones. A continuación, se analizan las alternativas de enseñanza en algunos libros de texto haciendo especial énfasis en sus características fundamentales. Como resultado, se concluye que la presentación de la dinámica clásica, tal como se hace actualmente, muestra deficiencias tanto de coherencia como de actualización, lo que sugiere la necesidad de una revisión general …

transposición didácticadinámica clásica; leyes de Newton; transposición didáctica; contenido curricularcontenido curriculardidáctica de la físicadinámica clásicaleyes de Newton
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EXTRACORPOREAL SHOCK WAVE THERAPY (ESWT) IN CHRONIC LOW BACK PAIN: A SYSTEMATIC REVIEW OF RANDOMIZED CLINICAL TRIALS

2020

Background: Extracorporeal Shock Wave Therapy (ESWT) has become a popular tool to treat musculoskeletal disorders and chronic low back pain. Aim of the study: To review the current scientific literature and assess the utility of ESWT in treating chronic low back pain. Methods: This systematic review was conducted from November 2019 to January 2020. Its purpose was to determine what the effectiveness is of the various forms of ESWT for the treatment of chronic low back pain. The critical review of the literature on the use of ESWT in chronic low back was made using the scientifically recognized medical databases PubMed, MEDLINE, Physiotherapy Evidence Database (PEDro) and Web of Science Core…

treatmentExtracorporeal shock wave therapybusiness.industryESWTshock wavesLow back painChronic low back painlaw.inventionRandomized controlled triallawAnesthesiamedicinemedicine.symptombusinesslow back painMedical Science Pulse
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