Search results for "yield"

showing 10 items of 1338 documents

Synthesis of fluorine-18 labeled sulfonureas as ?-cell imaging agents

2001

Tolbutamide (1) and glyburide (7) are hypoglycemic drugs used to stimulate insulin secretion in type 2 diabetic patients. We have synthesized their fluorine-18 labeled analogs, 1-[(4-[ 18 F]fluorobenzenesulfonyl)]-3-butyl]urea (p-[ 18 F]fluorotolbutamide, 3a) and N-{4-[β-(2-[ 18 F]fluoroethoxybenzene carboxamido)ethyl]benzenesulfonyl)-N'-cyclohexylurea (2-[ 18 F]fluoroethoxyglyburide, 6a) as β-cell imaging agents. Compound 3a was synthesized via two approaches: One-step synthesis via nucleophilic substitution of p-nitrotolbutamide (2) with K[ 18 F]/Kryptofix 2.2.2 in either CH 3 CN or DMSO gave a complicated mixture; a two-step synthesis via preparation and reaction of 4-[ 18 F]fluorobenzen…

medicine.drug_classStereochemistryOrganic ChemistryCarboxamideAlkylationBiochemistryChemical synthesisMedicinal chemistryHigh-performance liquid chromatographyAnalytical Chemistrychemistry.chemical_compoundTolbutamidechemistryYield (chemistry)Drug DiscoverymedicineUreaNucleophilic substitutionRadiology Nuclear Medicine and imagingSpectroscopymedicine.drugJournal of Labelled Compounds and Radiopharmaceuticals
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Effect of propylene glycol on pre- and post-partum performance by dairy ewes

2005

This study was carried out in order to determine the effects, after feeding propylene glycol to Valle del Belice ewes 30 days prepartum and 30 days postpartum, on metabolic profiles, body-condition score, milk yield, milk composition, milk clotting ability and the performance of suckling lambs. Ewes were blocked by parity, body-condition score and previous milk production, and assigned randomly to either a control diet or a diet containing propylene glycol fed at the rate of 80 g/ewe/day (low PG) or 160 g/ewe/day (high PG). Feeding propylene glycol prepartum decreased the concentration of BHBA and NEFA and increased the concentration of glucose in the ewes’ plasma. Milk yield from ewes fed …

medicine.medical_specialtyMilk yieldMilk proteinChemistryKeywords: EweMilk productionPolyvinyl alcoholEwechemistry.chemical_compoundfluids and secretionsAnimal scienceMilk yieldEndocrinologyNEFAPropylene glycolFood AnimalsPostpartumInternal medicineMilk fatKeywords: Ewe Propylene glycol Prepartum Postpartum Milk yieldmedicineAnimal Science and ZoologyComposition (visual arts)PrepartumSettore AGR/18 - Nutrizione E Alimentazione Animale
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Through-the-needle biopsy of pancreatic cystic lesions: stronger evidences of higher diagnostic yield compared with cytology

2020

No abstract available

medicine.medical_specialtyYield (engineering)business.industryBiopsy NeedleGastroenterologyCystic lesionCytologyNeedle biopsyHumansPancreaMedicineRadiology Nuclear Medicine and imagingRadiologyPancreatic CystbusinessPancreasPancreatic Cyst.HumanGastrointestinal Endoscopy
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Drainage großer Brustdrüsenabszesse unter ästhetischen und funktionellen Aspekten

1991

In 11 puerperal women, a breast abscess was treated by drainage from the inframammary fold. Eight patients wished to continue breast feeding. During the healing period, the babies were not breast fed on the operated side. In 3 patients, the skin over the abscess necrotised, resulting in a defect of 1 to 2 cm. In 2 patients, a small seroma had to be punctured after removing the drainage tube. Aesthetic results were judged by the patients as good. Resumation of suckling on the operated side revealed only 15 to 20% milk yield compared to that of the other breast. This treatment meets aesthetic and function-preserving criteria.

medicine.medical_specialtybusiness.industryMammary glandObstetrics and Gynecologymedicine.diseaseSurgerymedicine.anatomical_structureMilk yieldLarge breastSeromaMaternity and MidwiferymedicineInframammary foldDrainageAbscessbusinessBreast feedingGeburtshilfe und Frauenheilkunde
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Application of Molecular Topology for the Prediction of Reaction Yields and Anti-Inflammatory Activity of Heterocyclic Amidine Derivatives

2011

Topological-mathematical models based on multiple linear regression analyses have been built to predict the reaction yields and the anti-inflammatory activity of a set of heterocylic amidine derivatives, synthesized under environmental friendly conditions, using microwave irradiation. Two models with three variables each were selected. The models were validated by cross-validation and randomization tests. The final outcome demonstrates a good agreement between the predicted and experimental results, confirming the robustness of the method. These models also enabled the screening of virtual libraries for new amidine derivatives predicted to show higher values of reaction yields and anti-infl…

multilineal regression analysisQSAR analysisAmidinesAnti-Inflammatory AgentsQuantitative Structure-Activity RelationshipArticleCatalysismolecular topologylcsh:ChemistryInorganic ChemistryAmidineHeterocyclic Compounds 1-Ringchemistry.chemical_compoundComputational chemistryLinear regressionOrganic chemistryPhysical and Theoretical Chemistryyield reactionanti-inflammatory activitylcsh:QH301-705.5Molecular BiologySpectroscopyChemistryOrganic ChemistryGeneral MedicineComputer Science Applicationslcsh:Biology (General)lcsh:QD1-999Microwave irradiationMolecular topologyAlgorithmsamidine derivativesInternational Journal of Molecular Sciences
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Theory of storage implications in the European natural gas market

2023

The theory of storage stands that futures prices should be equal to the spot price plus the interest forgone in storing the commodity and the warehousing costs minus the convenience yield on the inventory. In this paper, we test several implications of the theory of storage on the pricing of United Kingdom natural gas futures. We obtain partial evidence for the theory of storage as a complete explanation of the pricing of this futures contract. Explicitly, (i) we obtain evidence to explain convenience yield seasonality with spot price volatility, unexpected demand shocks when supply is tight, inventory variations, and trading activity in the futures markets; (ii) we obtain indirect evidence…

natural gasEconomics and EconometricsUNESCO::CIENCIAS ECONÓMICASconvenience yieldfutures marketsFinanceJournal of Commodity Markets
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Optimization of the JUNO liquid scintillator composition using a Daya Bay antineutrino detector

2021

To maximize the light yield of the liquid scintillator (LS) for the Jiangmen Underground Neutrino Observatory (JUNO), a 20 t LS sample was produced in a pilot plant at Daya Bay. The optical properties of the new LS in various compositions were studied by replacing the gadolinium-loaded LS in one antineutrino detector. The concentrations of the fluor, PPO, and the wavelength shifter, bis-MSB, were increased in 12 steps from 0.5 g/L and 0.01 mg/L to 4 g/L and 13 mg/L, respectively. The numbers of total detected photoelectrons suggest that, with the optically purified solvent, the bis-MSB concentration does not need to be more than 4 mg/L. To bridge the one order of magnitude in the detector s…

neutrinoantimateriailmaisimetlight yieldtutkimuslaitteetneutriinothiukkasfysiikkaliquid scintillator
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Diels–Alder reaction of β-fluoro-β-nitrostyrenes with cyclic dienes

2021

The Diels–Alder reaction of β-fluoro-β-nitrostyrenes with cyclic 1,3-dienes was investigated. A series of novel monofluorinated norbornenes was prepared in up to 97% yield. The reaction with 1,3-cyclohexadiene permits the preparation of monofluorinated bicyclo[2.2.2]oct-2-enes. The kinetic data of the reactions with 1,3-cyclopentadiene and 1,3-cyclohexadiene were used to calculate activation parameters. Furthermore, the synthetic utility of the cycloadducts obtained was demonstrated.

nitrostyreneBicyclic moleculeChemistryOrganic Chemistrystereochemistrychemistry.chemical_elementnorborneneMedicinal chemistryFull Research Paperlcsh:QD241-441Chemistrychemistry.chemical_compoundlcsh:Organic chemistryDiels–Alder reactionfluorineYield (chemistry)Fluorinelcsh:Qlcsh:ScienceNorborneneDiels–Alder reactionBeilstein Journal of Organic Chemistry
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Vibrational Spectrum of HXeSH revisited : Combined computational and experimental study

2020

Vibrational spectrum of HXeSH embedded in low-temperature matrix is experimentally studied. To support the spectrum interpretation, anharmonic vibrational analysis is performed using different models and basis sets and the data is compared with previous experimental and theoretical analyses. Computations of overtones and combination modes allowed for new band assignments. The HXeSH molecule exhibits high anharmonicity similarly as other molecules from the noble-gas hydride family. Comparison of the employed computational methods shows once again that the modelling of the noble-gas compounds faces theoretical challenges to yield quantitatively reliable results. peerReviewed

noble gasXenonInfraredspektroskopiaGeneral Physics and AstronomyInfrared spectroscopyksenonhydride02 engineering and technology010402 general chemistry01 natural sciencesMolecular physicsMatrix (mathematics)värähtelytinfrapunasäteilyMoleculePhysical and Theoretical ChemistryPhysics::Chemical PhysicsPhysicsBasis (linear algebra)anharmonicityAnharmonicityMatrix isolationmatrix isolationjalokaasut021001 nanoscience & nanotechnologylaskennallinen kemiacomputational chemistryvibrational spectroscopy0104 chemical sciencesinfrared spectrumYield (chemistry)hydridit0210 nano-technology
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Recent experiments at the JYFLTRAP Penning trap

2020

AbstractThe JYFLTRAP double Penning trap mass spectrometer at the Ion Guide Isotope Separator On-Line (IGISOL) facility offers excellent possibilities for high-precision mass measurements of radioactive ions. Around 400 atomic masses, including around 50 isomeric states, have been measured since JYFLTRAP became operational. JYFLTRAP has also been used as a high-resolution mass separator for decay spectroscopy experiments as well as an ion counter for fission yield studies. In this contribution, an overview of recent activities at the JYFLTRAP Penning trap is given, with a focus on nuclei discussed in the PLATAN2019 meeting.

nuclear binding energymassaspektrometriaNuclear and High Energy PhysicstutkimuslaitteetFission product yieldMass spectrometry7. Clean energy01 natural sciencesIonNuclear physicsPhysics in General0103 physical sciencesPhysical and Theoretical Chemistry010306 general physicsSpectroscopyPhysicsIsotope010308 nuclear & particles physicsatomic masspenning trapCondensed Matter PhysicsPenning trapAtomic and Molecular Physics and OpticsAtomic massNuclear binding energyisomersydinfysiikkaHyperfine Interactions
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