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showing 10 items of 16837 documents

Lemierre syndrome: Current evidence and rationale of the Bacteria-Associated Thrombosis, Thrombophlebitis and LEmierre syndrome (BATTLE) registry.

2020

Abstract Lemierre syndrome is a rare but potentially fatal condition characterized by septic thrombophlebitis of the head and neck district, preferentially affecting adolescents and young adults and manifesting as a complication of a local bacterial infection – typically, a pharyngotonsillitis or an abscess. It is historically associated with the Gram-negative anaerobic rod Fusobacterium necrophorum and with thrombophlebitis of the internal jugular vein. However, its definition has never been firmly established, and its spectrum within the continuum of bacteria-associated thrombophlebitis may be larger than what presumed so far. Recent evidence suggests that its prognosis remains serious ev…

medicine.medical_specialtyAdolescent2720 Hematologyved/biology.organism_classification_rank.species610 Medicine & health030204 cardiovascular system & hematologyThrombophlebitis03 medical and health sciencesYoung Adult0302 clinical medicineDisease registryFusobacterium necrophorumEpidemiologymedicineHumansSeptic thrombophlebitisRegistriesAbscessIntensive care medicinebiologyved/biologybusiness.industry10031 Clinic for AngiologyHematologyLemierre SyndromeThrombophlebitisbiology.organism_classificationmedicine.diseasePharyngitisAnti-Bacterial AgentsFusobacterium necrophorumFusobacterium030220 oncology & carcinogenesismedicine.symptomJugular VeinsbusinessThrombosis research
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Choosing an ideal pharmacotherapeutic strategy for dyslipidemia in children.

2018

Dyslipdiemia can manifest at a young age, and it is a risk factor for atherosclerotic cardiovascular disease (ASCVD), the principal cause of mortality in developed nations. Therefore, treating it a...

medicine.medical_specialtyAdolescentFamilial hypercholesterolemiastatins03 medical and health sciences0302 clinical medicineEzetimibechildrenmedicinePharmacology (medical)Risk factorIntensive care medicinePharmacologyfamilial hypercholesterolemiaAtherosclerotic cardiovascular diseasebusiness.industryfungidyslipidemiafood and beveragesGeneral Medicinemedicine.diseaseYoung age030220 oncology & carcinogenesisbusinessDeveloped country030217 neurology & neurosurgeryDyslipidemiamedicine.drugezetimibeExpert opinion on pharmacotherapy
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Prevalence of Genital Human Papilloma Virus Infection and Genotypes among Young Women in Sicily, South Italy

2008

Abstract Infection with oncogenic human papilloma virus (HPV) types is a necessary cause of cervical cancer. This study assessed the prevalence of HPV infection and genotypes among 1,006 randomly selected women, ages 18 to 24 years, living in Sicily (south Italy). The overall HPV rate was 24.1% (95% confidence interval, 21.5-26.9). The most frequent types were HPV-16 (4.5%), HPV-53 (2.7%), and HPV-84 (2.6%). The prevalence of vaccine types HPV-6, HPV-11, and HPV-18 was 1.4%, 0.1%, and 1.3%, respectively. Cytologic abnormalities were uncommon (3.1%) and associated with HPV detection (P < 0.0001). The only risk factor for HPV infection was the number of sexual partners (women with 2-3 …

medicine.medical_specialtyAdolescentGenotypeEpidemiologyYoung AdultEpidemiologymedicinePrevalenceHumansSex organYoung adultPapillomaviridaeRisk factorfemale genotype Human papillomavirusPapillomaviridaeCervical cancerChi-Square Distributionbiologybusiness.industryObstetricsPapillomavirus InfectionsHPV infectionvirus diseasesOdds ratioSexually Transmitted Diseases Viralbiology.organism_classificationmedicine.diseasefemale genital diseases and pregnancy complicationsLogistic ModelsOncologyItalyImmunologyFemalebusiness
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Rotational flywheel training in youth female team sport athletes: could inter-repetition movement variability be beneficial?

2020

Background: The aim of this study was to analyse the effects of an inter-repetition variable rotational flywheel training program (Variable) over standard rotational flywheel training (Standard). Methods: Twenty-four youth female team-sports players were randomly assigned to both training groups (Variable, n = 12; Standard, n = 12), which consisted of 1 set of 3 rotational flywheel exercises x 10-12 repetitions, biweekly for a period of 6-weeks. The participants included in Variable group were instructed to perform the movement randomly in one of the three directions (0o, 45o right, and 45o left). Measurements included reactive strength, jumping, change of direction, and sprinting tests; pa…

medicine.medical_specialtyAdolescentTeam sportMovementPhysical Therapy Sports Therapy and RehabilitationAthletic Performancemedicine.disease_causeFlywheel03 medical and health sciencesVertical jump0302 clinical medicineJumpingPhysical medicine and rehabilitationmedicineHumansOrthopedics and Sports MedicineExercisebiologyAthletesMovement (music)Youth SportsTraining (meteorology)Resistance Training030229 sport sciencesbiology.organism_classificationAdaptation PhysiologicalLower ExtremityJumpFemalePsychology030217 neurology & neurosurgeryThe Journal of Sports Medicine and Physical Fitness
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Beta-adrenoceptor-mediated facilitation of endogenous noradrenaline release from rat isolated trachea.

1994

Overflow of endogenous noradrenaline from rat isolated trachea was evoked by electrical field stimulation (3 Hz, 540 pulses) in the presence of yohimbine, desipramine and tyrosine. Isoprenaline 100 nmol/l increased the evoked overflow of noradrenaline by about 65%. This effect was antagonized by propranolol (100 nmol/l) and the beta 2-selective adrenoceptor antagonist ICI 118,551 (100 nmol/l), but not by the beta 1-selective adrenoceptor antagonist CGP 20712 A (100 nmol/l). The beta 2-selective adrenoceptor agonist formoterol (1-100 nmol/l) also facilitated the evoked overflow of noradrenaline, but maximally by only about 25% at 10 nmol/l, i.e. formoterol behaved as a partial agonist at the…

medicine.medical_specialtyAdrenergic beta-AntagonistsIndomethacinAdrenergicPropranololIn Vitro TechniquesPartial agonistNorepinephrine (medication)Rats Sprague-DawleyNorepinephrineAdrenergic AgentsIsoprenalineInternal medicineReceptors Adrenergic betamedicineAnimalsPharmacologyChemistryAntagonistGeneral MedicineElectric StimulationYohimbineRatsTracheaEndocrinologycardiovascular systemFemaleFormoterolmedicine.drugSignal TransductionNaunyn-Schmiedeberg's archives of pharmacology
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Motor asymmetry attenuation in older adults during imagined arm movements

2014

International audience; Laterality is an important feature of motor behavior. Several studies have shown that lateralization in right-handed young adults (i.e., right versus left arm superiority) emerges also during imagined actions, that is when an action is internally simulated without any motor output. Such information, however, is lacking for elderly people and it could be valuable to further comprehend the evolution of mental states of action in normal aging. Here, we evaluated the influence of age on motor laterality during mental actions. Twenty-four young (mean age: 24.7 +/- 4.4 years) and 24 elderly (mean age: 72.4 +/- 3.6 years) participants mentally simulated and actually execute…

medicine.medical_specialtyAgingAGE-RELATED DIFFERENCESRIGHT HANDSCognitive NeuroscienceRight armNormal agingIMAGERYLeft armLateralization of brain functionDevelopmental psychologylcsh:RC321-571Physical medicine and rehabilitationMotor imageryArm musclemedicineYoung adultMotor asymmetrylcsh:Neurosciences. Biological psychiatry. NeuropsychiatryOriginal Researchmovement durationNONDOMINANT ARMMuscle activationCORTICOSPINAL EXCITABILITYAGING BRAINPERFORMANCEMENTAL SIMULATIONTEMPORAL FEATURESMotor asymmetryLateralityLIMB DYNAMICSMotor Imagery[ SCCO ] Cognitive sciencePsychologyNeuroscience
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Polycystic ovary syndrome: metabolic consequences and long-term management.

2014

Young women with polycystic ovary syndrome (PCOS) present an increased risk for type II diabetes and cardiovascular diseases. The prevalence of altered glucose tolerance ranges between 20 and 35 % in patients while the prevalence of type II diabetes ranges between 2 and 8 % and seems related to body weight and ethnic group. Moving from the young fertile age to the 40s and the menopause the prevalence of type II diabetes continues to increase compared to the general female population and may reach 10-16 % of PCOS women. However, prevalence of altered glucose tolerance does not increase. Also cardiovascular risk is increased in a large part of young PCOS women but this risk tends to be normal…

medicine.medical_specialtyAgingClinical BiochemistryPhysiologyAge DistributionRisk FactorsInternal medicineLong term managementmedicineHumansIn patientbusiness.industryGeneral Medicinemedicine.diseasePolycystic ovaryObesityAndrogen secretionMenopausePostmenopauseYoung ageEndocrinologyIncreased riskDiabetes Mellitus Type 2Cardiovascular DiseasesFemalebusinessPolycystic Ovary SyndromeScandinavian journal of clinical and laboratory investigation. Supplementum
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Motor unit discharge rate in dynamic movements of the aging soleus

2014

Aging is related to changes at the muscular level, leading to a decline in motor performance increasing the risk of falling and injury. It seems that the age-related changes in motor unit activation are muscle- and intensity dependent. The purpose of this study was to examine possible differences in soleus motor unit discharge rate (MUDR) in both isometric and dynamic contractions between young and elderly adults. 11 young (YOUNG) and 8 elderly (OLD) males participated in the study. The subjects performed isometric and dynamic plantar flexions while seated in an ankle dynamometer. The force levels studied were 10, 20, 40, 60, 80 and 100% of the isometric (ISO) MVC in ISO and 10, 20 and 40% …

medicine.medical_specialtyAgingDynamic contractionIsometric exerciseConcentricintramuscular electromyographyBehavioral NeurosciencePhysical medicine and rehabilitationmotor unitSoleusmedicineEccentricOriginal Research Articleta315Biological PsychiatrysoleusDynamometerbusiness.industryMotor unitagingIntramuscular electromyographyCoactivationIntensity (physics)Motor unitPsychiatry and Mental healthNeuropsychology and Physiological Psychologymedicine.anatomical_structureNeurologyPhysical therapysense organsdynamic contractionAnklebusinessNeuroscience
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Muscle hypertrophy, strength development, and serum hormones during strength training in elderly women with fibromyalgia.

2005

To examine the effects of strength training on maximal force, cross-sectional area (CSA), and electromyographic (EMG) activity of muscles and serum hormone concentrations in elderly females with fibromyalgia (FM).Twenty-six patients with FM were randomly assigned to a training (FMT; n = 13; mean age 60 years) or a control (FMC; n = 13; 59 years) group. FMT performed progressive strength training twice a week for 21 weeks. The measurements included maximal isometric and concentric leg extension forces, EMG activity of the vastus lateralis and medialis, CSA of the quadriceps femoris, and serum concentrations of testosterone (T), free testosterone (FT), growth hormone (GH), insulin-like growth…

medicine.medical_specialtyAgingFibromyalgiaWeight LiftingStrength trainingImmunologyIsometric exerciseElectromyographySeverity of Illness IndexMuscle hypertrophychemistry.chemical_compoundDehydroepiandrosterone sulfateRheumatologyReference ValuesInternal medicineFibromyalgiamedicineImmunology and AllergyHumansHormone metabolismMuscle SkeletalTestosteronePhysical Therapy ModalitiesAgedProbabilitymedicine.diagnostic_testbusiness.industryElectromyographyGeneral MedicineHypertrophyMiddle Agedmedicine.diseaseHormonesExercise TherapyEndocrinologyCross-Sectional StudiesTreatment OutcomechemistryPhysical FitnessFemalebusinessFollow-Up StudiesScandinavian journal of rheumatology
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OGT and OGA expression in postmenopausal skeletal muscle associates with hormone replacement therapy and muscle cross-sectional area

2013

Protein glycosylation via O-linked N-acetylglucosaminylation (O-GlcNAcylation) is an important post-translational regulatory mechanism mediated by O-GlcNAc transferase (OGT) and responsive to nutrients and stress. OGT attaches an O-GlcNAc moiety to proteins, while O-GlcNAcase (OGA) catalyzes O-GlcNAc removal. In skeletal muscle of experimental animals, prolonged increase in O-GlcNAcylation associates with age and muscle atrophy. Here we examined the effects of hormone replacement therapy (HRT) and power training (PT) on muscle OGT and OGA gene expression in postmenopausal women generally prone to age-related muscle weakness. In addition, the associations of OGT and OGA gene expressions with…

medicine.medical_specialtyAgingGlycosylationTime Factorsmedicine.drug_classPlyometric ExerciseBiologyta3111N-AcetylglucosaminyltransferasesBiochemistryGene Expression Regulation EnzymologicEndocrinologyDownregulation and upregulationInternal medicineGene expressionGeneticsmedicineHumansMuscle StrengthRNA Messengerta315Muscle SkeletalMolecular BiologyFinlandGlyceraldehyde 3-phosphate dehydrogenasePlyometric power trainingEstrogen Replacement Therapyta1182Age FactorsMuscle weaknessSkeletal muscleta3141Cell BiologyMiddle Agedbeta-N-AcetylhexosaminidasesMuscle atrophyPostmenopausePhenotypeTreatment OutcomeEndocrinologymedicine.anatomical_structureEstrogenbiology.proteinFemaleMuscle atrophymedicine.symptomProtein Processing Post-TranslationalMuscle ContractionMuscle contraction
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