Search results for "yo"

showing 10 items of 16837 documents

Effect of inhibition of the electrogenic Na+/K+ pump on the mechanical activity in the rat uterus.

1996

The effects of ouabain and K(+)-free solution were studied in estrogen-primed rat uterine strips under resting tone or repeatedly stimulated with KCl, acetylcholine or oxytocin applied for 20 minutes at 60 minute intervals. These effects were compared with those of the K+ channel opener cromakalim. In preparations under resting tone, ouabain (0.1 mM and 0.3 mM) induced rhythmic contractions which disappeared after 20-30 minutes whereas at a higher concentration (1 mM) it evoked a rapid, phasic response followed by a small tonic contraction. Exposure of the strip to a K(+)-free solution induced either rhythmic waves, which ceased after 8-10 minutes, or a single phasic contraction which was f…

medicine.medical_specialtyCromakalimPotassium ChannelsIn Vitro TechniquesOxytocinOuabainchemistry.chemical_compoundUterine ContractionInternal medicinemedicineAnimalsPharmacology (medical)BenzopyransPyrrolesNa+/K+-ATPaseEnzyme InhibitorsRats WistarOuabainPharmacologyTetraethylammoniumVoltage-dependent calcium channelUterusMyometriumPotassium channel blockerAcetylcholineRatsEndocrinologychemistryCalciumFemalemedicine.symptomSodium-Potassium-Exchanging ATPaseCromakalimmedicine.drugMuscle contractionFundamentalclinical pharmacology
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Binge Drinking among adolescents is related to the development of Alcohol Use Disorders: results from a Cross-Sectional Study

2018

AbstractBinge drinking (BD) is a common pattern of alcohol consumption among adolescents. At present few data are available on the possible relationship between BD and alcohol use disorders (AUD) in adolescents. The aim of this study was to assess the prevalence of BD and relationship between BD behavior and AUD among adolescents. A total of 2704 students attending 10 purposively selected high schools from three Italian provinces were surveyed. Questionnaires regarding socio-demographic data, pattern and amount of alcohol intake, smoking habits, use of illicit drugs, and physical activity were administered. AUD and affective disorders were also evaluated. Alcohol intake was reported by 2126…

medicine.medical_specialtyCross-sectional studylcsh:MedicineBinge drinkingAlcoholLogistic regressionArticle03 medical and health scienceschemistry.chemical_compound0302 clinical medicinemental disordersmedicine030212 general & internal medicineYoung adultlcsh:SciencePsychiatryMultidisciplinarybusiness.industrylcsh:RSettore MED/09 - MEDICINA INTERNAchemistryPositive relationshiplcsh:QAlcohol intakebusinessAlcohol consumption030217 neurology & neurosurgeryScientific Reports
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Evaluation of the UP4FUN Intervention: A Cluster Randomized Trial to Reduce and Break Up Sitting Time in European 10-12-Year-Old Children

2015

Background The UP4FUN intervention is a family-involved school-based intervention aiming at reducing and breaking up sitting time at home (with special emphasis on screen time), and breaking up sitting time in school among 10–12 year olds in Europe. The purpose of the present paper was to evaluate its short term effects. Methodology/Principal Findings A total of 3147 pupils from Belgium, Germany, Greece, Hungary and Norway participated in a school-randomized controlled trial. The intervention included 1–2 school lessons per week for a period of six weeks, along with assignments for the children and their parents. Screen time and breaking up sitting time were registered by self-report and to…

medicine.medical_specialtyCross-sectional studylcsh:MedicineYOUNG-PEOPLE030209 endocrinology & metabolismMotor Activitylaw.invention03 medical and health sciencesScreen time0302 clinical medicineRandomized controlled triallawIntervention (counseling)Medicine and Health SciencesCROSS-SECTIONAL SURVEYmedicineHumansBALANCE-RELATED BEHAVIORSHome education030212 general & internal medicineCluster randomised controlled trialMotor activityProgram DevelopmentSCREEN TIMElcsh:ScienceChildEXCESSIVE WEIGHT-GAINMultidisciplinarybusiness.industrylcsh:RSEDENTARY BEHAVIORHEALTH INDICATORSSitting time3. Good healthEuropePHYSICAL-ACTIVITYMEDIA USEPhysical therapylcsh:QENERGY-PROJECTbusinessResearch ArticlePLoS ONE
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Preparation and karyotype analysis of mitotic chromosomes of the freshwater sponge Spongilla lacustris.

1993

The present study documents for the first time the karyotype and mitotic chromosomes of a sponge. For the studies the freshwater sponge Spongilla lacustris (Lin. 1758) was used. Its karyotype comprises nine different chromosome pairs ranging in size from 2.1 to < or = 0.7 microns. Changes in size and shape of the chromosomes during the progression of mitosis are documented both light and electron microscopically. The data reveal that the lowest multicellular eukaryotes, the sponges, have already reached a high level of evolution of the mitotic mechanism.

medicine.medical_specialtyCytogeneticsZoologyChromosomeMitosisKaryotypeDNABiologybiology.organism_classificationPoriferaSpongeMicroscopy ElectronSpongilla lacustrisKaryotypingGeneticsMicrochromosomemedicineAnimalsMitosisDevelopmental biologyGenetics (clinical)Chromosoma
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Tendencias de la mortalidad por cáncer en españa, en especial del cáncer de pulmón, en comparación con otros países desarrollados

1994

ResumenSe estudia la evolución de la mortalidad global por cáncer en España (1970–1987), y especialmente por cáncer de pulmón, por sexos y grupos de edad, estableciendo comparaciones con otros países (EEUU, Inglaterra y Gales).En cuanto a la evolución de la mortalidad global por cáncer se observa que únicamente en las edades más juveniles se detectan descensos notables de la mortalidad, en tanto que, en los otros países con los que se compara, se observa también una disminución en edades más avanzadas. Asimismo, aunque las tasas de mortalidad por cáncer de pulmón en España tienen unos valores inferiores a los de los países mencionados, se observa un incremento de la mortalidad de ambos sexo…

medicine.medical_specialtyCáncer de pulmónEpidemiologybusiness.industryPublic Health Environmental and Occupational HealthCancerCáncermedicine.diseaseYoung ageAge groupsMortalidadEpidemiologyEpidemiologíaMedicineMortalityLung cancerbusinessMortality trendsLung cancerLower mortalityDeveloped countryCancerDemographyGaceta Sanitaria
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The Use of a Nonimmersive Virtual Reality Programme in Anorexia Nervosa: A Single Case-Report

2011

Objective: People with anorexia nervosa (AN) experience high levels of fear and anxiety related to eating. The aim of this case report was to describe the use of a virtual reality (VR) programme developed to facilitate exposure to food as a supplement to treatment for a person with AN. Method: A 21-year-old patient with AN was given the VR module in addition to the Maudsley Model of Treatment for Adults with Anorexia Nervosa. Weight, eating disorder symptomatology (EDE-Q) and general psychopathology (DASS) were assessed before and after the module was delivered. Results: At the end of the module, the patient reported lower levels of anxiety, safety behaviours and fears related to food. Both…

medicine.medical_specialtyDASSdigestive oral and skin physiologymedicine.diseasePsychiatry and Mental healthClinical PsychologyDistressEating disordersAnorexia nervosa (differential diagnoses)Severity of illnessmedicineAnxietyYoung adultmedicine.symptomPsychologyPsychiatryBody mass indexClinical psychologyEuropean Eating Disorders Review
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A fully automatic 2D segmentation method for uterine fibroid in MRgFUS treatment evaluation

2015

PurposeMagnetic Resonance guided Focused UltraSound (MRgFUS) represents a non-invasive surgical approach that uses thermal ablation to treat uterine fibroids. After the MRgFUS treatment, an operator must manually segment the treated fibroid areas to evaluate the NonPerfused Volume (NPV). This manual approach is operator-dependent, introducing issues of result reproducibility, which could lead to errors in the subsequent follow-up phase. Moreover, manual segmentation is time-consuming, and can have a negative impact on the optimization of both machine-time and operator-time. MethodTo address these issues, in this paper a novel fully automatic method based on the unsupervised Fuzzy C-Means cl…

medicine.medical_specialtyDatabases FactualUterine fibroidsComputer scienceAdaptive thresholdingImage ProcessingAdaptive thresholding; Automatic segmentation; Fuzzy C-Means clustering; MRgFUS treatment; Uterine fibroids; Female; Humans; Image Processing Computer-Assisted; Leiomyoma; Radiography; Algorithms; Databases Factual; Magnetic Resonance Imaging; Ultrasonography InterventionalHealth InformaticsFuzzy logicDatabasesComputer-AssistedImage Processing Computer-AssistedmedicineHumansSegmentationCluster analysisFactualUltrasonography InterventionalUltrasonographySettore ING-INF/05 - Sistemi Di Elaborazione Delle InformazioniInterventionalLeiomyomaPixelbusiness.industryPattern recognitionmedicine.diseaseMagnetic Resonance ImagingFuzzy C-Means clusteringComputer Science ApplicationsSurgeryRadiographyTreatment evaluationMRgFUS treatmentFully automaticFemaleManual segmentationArtificial intelligenceAutomatic segmentationAdaptive thresholding Automatic segmentation Fuzzy C-Means clustering MRgFUS treatment Uterine fibroidsbusinessAlgorithmsUterine fibroids
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Data-driven discovery of changes in clinical code usage over time: a case-study on changes in cardiovascular disease recording in two English electro…

2020

[EN] Objectives To demonstrate how data-driven variability methods can be used to identify changes in disease recording in two English electronic health records databases between 2001 and 2015. Design Repeated cross-sectional analysis that applied data-driven temporal variability methods to assess month-by-month changes in routinely collected medical data. A measure of difference between months was calculated based on joint distributions of age, gender, socioeconomic status and recorded cardiovascular diseases. Distances between months were used to identify temporal trends in data recording. Setting 400 English primary care practices from the Clinical Practice Research Datalink (CPRD GOLD) …

medicine.medical_specialtyDatabases Factualstatistics & research methodsLibrary scienceHealth InformaticsDiseaseHealth records030204 cardiovascular system & hematologycomputer.software_genreAngina03 medical and health sciencesWelsh0302 clinical medicinecardiovascular diseaseHumans1702data qualityMedicine1506Myocardial infarction030212 general & internal medicineMedical diagnosisOriginal ResearchData collectionDatabasebusiness.industryPublic healthRClinical CodingGeneral Medicinemedicine.diseaseMedical researchNASA Chief Scientistlanguage.human_language3. Good healthSocial researchCross-Sectional Studieselectronic health recordsCardiovascular DiseasesFISICA APLICADAConcomitantHeart failureData qualitylanguageMedicinebusinesscomputerCareer developmentBMJ Open
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Cardiovascular imaging in the diagnosis and monitoring of cardiotoxicity: cardiovascular magnetic resonance and nuclear cardiology

2016

Chemotherapy-induced cardiotoxicity (CTX) is a determining factor for the quality of life and mortality of patients administered potentially cardiotoxic drugs and in long-term cancer survivors. Therefore, prevention and early detection of CTX are highly desirable, as is the exploration of alternative therapeutic strategies and/or the proposal of potentially cardioprotective treatments. In recent years, cardiovascular imaging has acquired a pivotal role in this setting. Although echocardiography remains the diagnostic method most used to monitor cancer patients, the need for more reliable, reproducible and accurate detection of early chemotherapy-induced CTX has encouraged the introduction o…

medicine.medical_specialtyDiagnostic methodspositron emission tomographycardiotoxicityEarly detectionAntineoplastic Agents030204 cardiovascular system & hematologynuclear cardiologyVentricular Function Left030218 nuclear medicine & medical imagingAntineoplastic Agent03 medical and health sciencescardiovascular magnetic resonance0302 clinical medicineQuality of lifeNeoplasmsInternal medicineEarly DiagnosimedicineHumanscardiotoxicity; cardiovascular magnetic resonanceCardiotoxicitymedicine.diagnostic_testbusiness.industryMyocardiumcardiotoxicity; cardiovascular magnetic resonance; nuclear cardiology; positron emission tomography; Antineoplastic Agents; Cardiotoxicity; Echocardiography; Humans; Neoplasms; Quality of Life; Early Diagnosis; Magnetic Resonance Imaging; Positron-Emission TomographyCancerMagnetic resonance imagingGeneral Medicinemedicine.diseaseMagnetic Resonance ImagingOxygenEarly DiagnosisCardiovascular DiseasesPositron emission tomographyEchocardiographyPositron-Emission TomographyCardiologyQuality of Lifecardiotoxicity cardiovascular magnetic resonance nuclear cardiology positron emission tomographyNeoplasmCardiology and Cardiovascular MedicineCardiac magnetic resonancebusinessHuman
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First-trimester neck abnormalities: three-dimensional evaluation.

1998

In order to study the first trimester ultrasonographic differences between nuchal translucency and hygroma colli, we rescanned 25 fetuses (13 with nuchal translucency and 12 with hygroma colli) using transvaginal and three-dimensional ultrasonography, after obtaining a fetal karyotype report. Our objective was to test the premise that the different physiopathologic mechanisms of both processes would be reflected in detectable sonographic differences. Our retrospective analysis showed that the most striking ultrasonographic difference was the presence of bullae as well as greater irregularity, extent, and amplitude of the membrane in cases of hygroma colli. Fetuses with simple nuchal translu…

medicine.medical_specialtyDiagnostico diferencialUltrasonography PrenatalNuchal translucencyPregnancymedicineRetrospective analysisHumansRadiology Nuclear Medicine and imagingHygroma colliRetrospective StudiesRadiological and Ultrasound Technologybusiness.industrySurgeryFirst trimesterFetal DiseasesPregnancy Trimester FirstHomogeneousHead and Neck NeoplasmsKaryotypingFemaleRadiologyLymphangioma CysticUltrasonographybusinessNeckJournal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
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