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showing 10 items of 16837 documents

Residual coronary stenosis after thrombolysis with rt-PA or streptokinase: acute results and 3 weeks follow-up

1987

Ninety-one patients with acute myocardial infarction were assigned to intravenous treatment with streptokinase or rt-PA as part of the randomized trial carried out by the European Study Group for Recombinant Tissue-Type Plasminogen Activator (rt-PA). A patent coronary artery was found in 37 of 45 (82%) patients treated with rt-PA and in 27 of 46 (59%) patients treated with streptokinase 75-90 minutes after start of infusion. Patients were subsequently anticoagulated with heparin or dicoumarol up to a repeat angiography 3 weeks after the infarction. Of the 64 patients with successful reperfusion, 3 died and 3 suffered reocclusion of the vessel. Quantitative analysis of the coronary stenosis …

medicine.medical_specialtymedicine.medical_treatmentStreptokinaseInfarctionCoronary DiseaseCoronary AngiographyRandom AllocationReperfusion therapyRecurrenceInternal medicineHumansMedicineStreptokinaseMyocardial infarctionVascular PatencyClinical Trials as Topicmedicine.diagnostic_testbusiness.industryHeparinThrombolysisMiddle Agedmedicine.diseaseRecombinant Proteinsmedicine.anatomical_structureTissue Plasminogen ActivatorAngiographyCardiologyCineangiographyRadiographic Image Interpretation Computer-AssistedCardiology and Cardiovascular MedicinebusinessFollow-Up Studiesmedicine.drugArteryEuropean Heart Journal
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HDlive imaging of cystic uterine leiomyoma degeneration

2016

medicine.medical_specialtymedicine.medical_treatmentTreatment outcomeDegeneration (medical)03 medical and health scienceschemistry.chemical_compound0302 clinical medicineUlipristal acetatemedicineRadiology Nuclear Medicine and imaging030212 general & internal medicine030219 obstetrics & reproductive medicineHysterectomyUterine leiomyomaRadiological and Ultrasound Technologymedicine.diagnostic_testbusiness.industryObstetrics and GynecologyMagnetic resonance imagingGeneral Medicinemedicine.diseaseLeiomyomaReproductive MedicinechemistryRadiologyUltrasonographybusinessUltrasound in Obstetrics & Gynecology
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Fragmentation of bile duct stones: a prospective systematic in vitro evaluation of argon plasma coagulation, cryotechnology, and water-jet technology

2009

Background and study aim Choledocholithiasis is a common disease in the West. Lithotripsy by mechanical methods using baskets and by laser or electrohydraulic methods varies in effectiveness. With argon plasma coagulation (APC), high temperatures are used for devitalization and fragmentation; cryogenic techniques use the selective controlled application of freeze-thaw cycles to devitalize pathological tissue; and the dissecting water jet exploits the high pressure action of a thin laminar jet. We aimed to assess the feasibility and effectiveness of APC, cryotechnology, and the dissecting water jet as options for the fragmentation of bile duct stones. Methods In an in vitro feasibility study…

medicine.medical_specialtymedicine.medical_treatmentUrologyArgon plasma coagulationGallstonesIn Vitro TechniquesLithotripsyCryosurgeryElectrocoagulationLithotripsyElectrocoagulationPressuremedicineHumansArgonFragmentation (cell biology)Jet (fluid)Bile ductbusiness.industryGastroenterologyWaterWater jetSurgeryCholedocholithiasismedicine.anatomical_structureFragmentation rateFeasibility StudiesbusinessEndoscopy
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Identification of Flow-Limiting Coronary Stenosis With PCS: A New Cost-Effective Index Derived From the Product of Corrected TIMI Frame Count and Per…

2021

Background: Identifying functional coronary stenosis with simple and cost-effective methods during invasive coronary angiography is still challenging. Corrected TIMI frame count (CTFC) is considered to be the frame count velocity of coronary blood flow. We aimed to propose a simple and cost-effective index based on CTFC and percent diameter stenosis (DS) to identify flow-limiting coronary stenosis. For this, a new index was put forward as the product of CTFC and DS (PCS). PCS can be regarded as the loss of coronary blood flow due to diameter stenosis.Methods: DS, CTFC, PCS, and Fractional flow reserve (FFR) of 111 vessels in 84 patients with suspected coronary heart disease were measured. F…

medicine.medical_specialtymedicine.medical_treatmentYouden's J statisticFractional flow reserveCardiovascular MedicinePercent Diameter StenosisCoronary artery diseaseInternal medicinemedicineDiseases of the circulatory (Cardiovascular) systemfractional flow reserveOriginal Researchbusiness.industrypercutaneous coronary interventionPercutaneous coronary interventioncorrected TIMI frame countBlood flowmedicine.diseaseflow-limiting coronary stenosisStenosisRC666-701CardiologyCardiology and Cardiovascular MedicinebusinessTIMIcoronary artery diseaseFrontiers in Cardiovascular Medicine
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Multivessel Intervention in Myocardial Infarction with Cardiogenic Shock: CULPRIT-SHOCK Trial Outcomes in the PL-ACS Registry

2021

Background: The aim of the study was a comparison of culprit-lesion-only (CL-PCI) with the multivessel percutaneous coronary intervention (MV-PCI) in terms of 30-day and 12-month mortality in a national registry. Methods: Patients from the PL-ACS registry with MI and CS were analyzed. Patients meeting the criteria of the CULPRIT-SHOCK trial were divided into two groups: CL-PCI and MV-PCI groups. Results: Of the 3265 patients in the PL-ACS registry with MI complicated by CS, the criteria of the CULPRIT-SHOCK trial were met by 2084 patients (63.8%). The CL-PCI was performed in 883 patients, and MV-PCI was performed in 1045 patients. After the propensity score matching analysis, 617 well-match…

medicine.medical_specialtymedicine.medical_treatmentacute myocardial infarction030204 cardiovascular system & hematologyRevascularizationacute myocardial infarction; cardiogenic shock; percutaneous coronary interventionCulpritArticle03 medical and health sciences0302 clinical medicineInternal medicineMedicinecardiovascular diseases030212 general & internal medicineMyocardial infarctionbusiness.industryCardiogenic shockcardiogenic shockpercutaneous coronary interventionRPercutaneous coronary interventionGeneral Medicinemedicine.diseasesurgical procedures operativemedicine.anatomical_structureShock (circulatory)Propensity score matchingMedicinemedicine.symptombusinessArteryJournal of Clinical Medicine
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Long-Term Outcome with New Generation Prostheses in Patients Undergoing Transcatheter Aortic Valve Replacement

2021

The aim of this study was to compare patients with transcatheter aortic valve replacement (TAVR) receiving new generation prostheses SAPIEN 3 (S3, Edwards Lifesc.) and Evolut R (ER, Medtronic Inc.) in terms of periprocedural and long-term outcome. Our retrospective, single-center analysis included 359 consecutive patients with severe aortic stenosis who underwent TAVR with S3 or ER from 2014–2016 (mean age 82 ± 7 years, 47% male, mean EuroSCORE II 8.0 ± 8%, mean follow-up 3.8 years). Device Success was equal (S3 93.0% vs. ER 92.4%, p = 0.812). We report a 30-day mortality of 2.8% in the S3 group, and 2.1% in the ER group (p = 0.674). There was no difference in stroke, conversion to open sur…

medicine.medical_specialtymedicine.medical_treatmentaortic valve stenosis030204 cardiovascular system & hematologyTAVRnew-generation trans-catheter heart valvesProsthesisArticle03 medical and health sciences0302 clinical medicineValve replacementInternal medicinemedicine030212 general & internal medicineMyocardial infarctionStrokeEjection fractionbusiness.industryRGeneral Medicinemedicine.diseaseStenosisAortic valve stenosisCardiologyMedicineImplantbusinesslong-term outcomesJournal of Clinical Medicine
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Effect of ischemic postconditioning on microvascular obstruction in reperfused myocardial infarction. Results of a randomized study in patients and o…

2014

Background: Ischemic postconditioning (PCON) appears as a potentially beneficial tool in ST-segment elevation myocardial infarction (STEMI). We evaluated the effect of PCON on microvascular obstruction (MVO) in STEMI patients and in an experimental swine model. Methods: A prospective randomized study in patients and an experimental study in swine were carried out in two university hospitals in Spain. 101 consecutive STEMI patients were randomized to undergo primary angio-plasty followed by PCON or primary angioplasty alone (non-PCON). Using late gadolinium enhancement cardiovascular magnetic resonance, infarct size and MVO were quantified (% of left ventricular mass). In swine, using an ang…

medicine.medical_specialtymedicine.medical_treatmentlaw.inventionTECNOLOGIA ELECTRONICARandomized controlled triallawInternal medicineAngioplastymedicineIn patientMyocardial infarctioncardiovascular diseasesIschemic postconditioningEjection fractionmedicine.diagnostic_testExperimental modelbusiness.industryIschemic postconditioning Myocardial infarction PerfusionMagnetic resonance imagingmedicine.diseasePerfusionMyocardial infarctionsurgical procedures operativeCardiologyCardiology and Cardiovascular MedicinebusinessPerfusion
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A method of reconstruction after pancreaticoduodenectomy for pancreatic malignancies in very young children: Two cases reports

2016

Abstract Pancreatic tumors are very rare diseases in very young children. Most information about those diseases in children was published in cases reports. Due to the rare nature of pancreatic tumors in children, there remains the absence of diagnostic algorithms, clear radiographic and morphological assessments as well as evidence based best treatment options. Because of the young age of patients and the rare occurrence of pancreatic neoplasms, tumor detection remains poor. For malignancies affecting the head of the pancreas the only possibility for achieving clear surgical margins is performing a pancreaticoduodenectomy (PD). We describe two cases of diagnostic and treatment of pancreatic…

medicine.medical_specialtymedicine.medical_treatmentlcsh:SurgeryYoung childrenPancreaticoduodenectomy03 medical and health sciencesPancreatic tumor0302 clinical medicinePancreatic tumormedicinePancreatic tumors; Pancreaticoduodenectomy; Young children; Pediatrics Perinatology and Child Health; SurgeryPancreatic tumorsbusiness.industryGeneral surgerySettore MED/20 - Chirurgia Pediatrica E Infantilelcsh:RJ1-570Treatment optionslcsh:PediatricsDiagnostic algorithmslcsh:RD1-811medicine.diseasePancreaticoduodenectomySettore MED/18 - Chirurgia GeneraleYoung ageTumor detection030220 oncology & carcinogenesisPediatrics Perinatology and Child Health030211 gastroenterology & hepatologySurgerybusinessJournal of Pediatric Surgery Case Reports
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Online gambling: A treatment for sports betting addiction

2020

Resumen Antecedentes : el juego de azar online (apuestas, juegos de casino, póquer, etc.) es una actividad que se está extendiendo mundialmente, incluso en los países en los cuales todavía no está legalizado. A pesar de que la situación en Latinoamérica es de lo más diversa, es probable que conforme se desarrolle y promocione el juego online aparezcan problemas de adicción, de forma similar a lo que está ocurriendo en España desde que este tipo de juegos se legalizó en 2011. De manera que la ciencia psicológica debe ir desarrollando programas de tratamiento que hagan frente a la nueva realidad. Objetivo: el artículo presenta el procedimiento seguido para el tratamiento de un joven con probl…

medicine.medical_specialtymedicine.medical_treatmentmedia_common.quotation_subjectOnline gamblingtrastorno por juego de apuestasPromotion (rank)tratamientojuego ético.online gamblingIntervention (counseling)medicinePsychologyPsychiatryjuventudmedia_commonLegalizationyouthtreatmentAddictionTreatment phasesjuego onlinegambling disorderjuego éticoBF1-990Cognitive behavioral therapyethical gambling.Test scoreadicción al juegoPsychologygambling addiction
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Microvascular Obstruction in ST-Segment Elevation Myocardial Infarction: Looking Back to Move Forward. Focus on CMR

2019

After a myocardial infarction (MI), despite the resolution of the coronary occlusion, the deterioration of myocardial perfusion persists in a considerable number of patients. This phenomenon is known as microvascular obstruction (MVO). Initially, the focus was placed on re-establishing blood flow in the epicardial artery. Then, the observation that MVO has profound negative structural and prognostic repercussions revived interest in microcirculation. In the near future, the availability of co-adjuvant therapies (beyond timely coronary reperfusion) aimed at preventing, minimizing, and repairing MVOs and finding convincing answers to questions regarding what, when, how, and where to administe…

medicine.medical_specialtymicrovascular obstructionlcsh:MedicineReview030204 cardiovascular system & hematologyMicrocirculation03 medical and health sciences0302 clinical medicineInternal medicinemedicineST segmentIn patient030212 general & internal medicineMyocardial infarctionbusiness.industrylcsh:RGeneral MedicineBlood flowreperfusion injurymedicine.diseasemyocardial infarctionmedicine.anatomical_structureCoronary occlusionCardiologybusinessReperfusion injuryArteryJournal of Clinical Medicine
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