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Causal analysis of short-term cardiovascular variability: state-dependent contribution of feedback and feedforward mechanisms.
2016
Baroreflex function is usually assessed from spontaneous oscillations of blood pressure (BP) and cardiac RR interval assuming a unidirectional influence from BP to RR. However, the interaction of BP and RR is bidirectionalâRR also influences BP. Novel methods based on the concept of Granger causality were recently developed for separate analysis of feedback (baroreflex) and feedforward (mechanical) interactions between RR and BP. We aimed at assessing the proportion of the two causal directions of the interactions between RR and systolic BP (SBP) oscillations during various conditions, and at comparing causality measures from SBP to RR with baroreflex gain indexes. Arterial BP and ECG sig…
Cardiovascular magnetic resonance-derived aortic compliance, distensibility and pulse wave velocity at rest and during a supine bicycle exercise in y…
2014
Background Purpose: Risk of aortic rupture is evaluated based on the vessel diameter; this parameter is probably insufficient. In vivo evaluation of biomechanical property of the aortic tissue might be of interest to discriminate between normal and altered aortic tissue (A Lalande et al, JMRI 2008). The purpose of this study was to describe a technique to measure regional aortic compliance (AC), aortic distensibility (AD) and aortic stiffness with 1.5 T MRI in young individuals under resting conditions and during supine bicycle exercise.
Clinical evaluation of the European LeukaemiaNet criteria for clinicohaematological response and resistance/intolerance to hydroxycarbamide in essent…
2010
Standardized criteria of response to treatment and a unified definition of resistance/intolerance to hydroxycarbamide (HC) in essential thrombocythaemia (ET) have been proposed by the European LeukaemiaNet (ELN). We have retrospectively evaluated such criteria in 166 ET patients treated with HC for a median of 4·5 years. Overall, 134 patients achieved a complete clinicohaematological response (CR) and 25 a partial response. Thirty-three patients met at least one of the ELN criteria defining resistance (n = 15) or intolerance (n = 21) to HC. Fifteen cases developed anaemia with thrombocytosis, which was associated with a high incidence of myelofibrosis and death from any cause. Other definit…
Toothguide Training Box for Dental Color Choice Training
2011
The purpose of this study was to evaluate the use of the Toothguide Training Box (TTB) for training dental students in color identification. The seventy-four volunteers who took part in the study attended a seminar on the Vita 3D Master Guide (MG) and the TTB system as well as a demonstration of the equipment before training began. At the end of the training they took the TTB final test. In addition, the participants were asked to recognize ten MG shade tabs in a blind manner before and after TTB training. The training times and percentages of correct answers were compared using the paired t-test. Variations in scores with training times and percentages of correct answers before and after t…
Is GH dosing optimal in female patients with adult-onset GH deficiency? An analysis from the NordiNet® International Outcome Study
2017
SummaryObjective To evaluate gender differences in GH dosing, IGF-I and cardiovascular risk markers in adults with GH deficiency (GHD). Design NordiNet® International Outcome Study (NCT00960128), a noninterventional, multicentre study, evaluates the long-term effectiveness and safety of Norditropin® (Novo Nordisk A/S) in the real-life clinical setting. Patients Nondiabetic patients (n = 252; 41·7% female) with adult-onset GHD (age ≥20 years at GH start), ≥4 years’ GH therapy and glycosylated haemoglobin (HbA1c) data at baseline and 4 years. Measurements Effects of gender (adjusted for baseline age and body mass index [BMI], average GH dose, treatment duration and concomitant medication) on …
Esthesioneuroblastoma presenting with epifora in a young child
1997
Esthesioneuroblastoma (ENB) is an uncommon tumor believed to arise from the olfactory epithelium. 1 This neoplasm has rarely been reported in children, with only 12 cases reported to date among patients younger than 10 years. 2 The usual initial symptom in children, as in older patients, is nasal obstruction or epistaxis 3 ; consequently, the tumor is often first seen by an otorhinolaryngologist. We report a case of ENB in a young child in whom the initial symptom was epiphora; to our knowledge, this initial symptom is previously unreported, and ENB must now be considered in the differential diagnosis of epiphora in childhood. Report of a Case. A white 6-year-old male child was seen on Janu…
Gender and Age Group Differences in Stereotypes about Mental Health Care Providers
2013
Mental health care providers play a significant role in the prevention of mental health problems and promotion of well-being. The aim of the study was to explore gender and age group differences in stereotypes about helping professionals in the mental health care field. The data were derived from 338 Latvian-speaking adults aged 18 to 87. They rated stereotypic characteristics of five typical helping professionals (a family doctor, a psychologist, a psychiatrist, a clergyman, and an astrologer) on a seven-point Likert-type scale. The stereotype content model was used to measure warmth and competence stereotypes (Fiske, Xu, Cuddy, & Glick, 1999). Gender differences show that women rate a typ…
Incidence and Risk Factors for Tractional Macular Detachment after Anti-Vascular Endothelial Growth Factor Agent Pretreatment before Vitrectomy for C…
2019
The study&rsquo
A School-Based Randomized Controlled Trial to Promote Cycling to School in Adolescents: The PACO Study
2021
This manuscript describes the rationale and protocol of a school-based randomized controlled trial called “Cycling and Walk to School” (PACO, by its Spanish acronym) that aims to promote cycling to and from school and physical activity (PA) in adolescents. This study will examine the effects of this intervention in cycling and active commuting to and from school (ACS), PA and several ACS-related factors based on self-determination theory (SDT) and a social-ecological model (SEM). A total of 360 adolescents attending six high schools (three experimental and three control) from three Spanish cities will participate in this randomized controlled trial. The intervention (four cycling sessions; …
Differences in the Motor Coordination Abilities Among Adolescent Gymnasts, Swimmers, and Ice Hockey Players
2017
AbstractPurpose. Motor coordination is proposed to be a relatively stable age-related construct, unlikely to be influenced by aligned experiential factors such as intensive sport-specific training. The purpose of the study is to investigate if there are differences in motor coordination abilities among young artistic gymnasts, swimmers, and ice hockey players.Methods. The participants of the study were 508 female and 258 male adolescents (age, M = 12.80, SD = 1.10) comprising artistic gymnasts (n = 463), swimmers (n = 70), and ice hockey players (n = 233). The KTK-test protocol was used to analyse their gross motor coordination abilities.Results. The results of the study demonstrated that g…