Search results for "Β-oxydation"
showing 2 items of 2 documents
Molecular basis of the effects of argan oil on mitochondrial and peroxisomal metabolism of the fatty acids and inflammation
2012
The objective of this thesis work was to explore the molecular basis of Argan Oil (AO) effects on the mitochondrial and peroxisomal lipid metabolism and to elucidate its anti-inflammatory potential. We thus showed, initially, that the artisanal method preparation preserved the antioxidant properties of AO preventing the oxidation of the ferulic acid, by contrast to AO of commercial origin. Then, the treatment by the AO or lipopolysaccharides (LPS) of human fibroblasts, the cellular model of pseudo-neonatal adrenoleukodystrophy (P-NALD), revealed for the AO that peroxisomes proliferation is independent from the activation of the nuclear receptor PPARα and the co-activator PGC-1α. On the othe…
Aroma production by solid state fermentation
2018
The adaptation of the production of γ-decalactones from submerged fermentation (SmF) to solid state fermentation (SSF) by Yarrowia lipolytica was investigated in this work. First of all, different solid matrices (corncob, cellulose sponge, luffa sponge, and castor seeds) were used for the first adaptation of the production of γ-décalactones. Luffa sponge appeared to be the most interesting solid support on which lactones were produced in higher concentrations than in the other solid matrices used. Then, the production of lactones using luffa sponge as the solid support was carried out in three types of SSF reactors to monitor different aeration conditions (without aeration, with a static ae…