Search results for "σ"

showing 10 items of 40 documents

Sigma-fragmentability and the property SLD in C(K) spaces

AbstractWe characterize two topological properties in Banach spaces of type C(K), namely, being σ-fragmented by the norm metric and having a countable cover by sets of small local norm-diameter (briefly, the property norm-SLD). We apply our results to deduce that Cp(K) is σ-fragmented by the norm metric when K belongs to a certain class of Rosenthal compacta as well as to characterize the property norm-SLD in Cp(K) in case K is scattered.

Countable cover by sets of small local diameterRosenthal compactaRenormingsσ-fragmentabilityTopology and its Applications
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N-[2-(2,2-Di­methyl­propanamido)­pyrimidin-4-yl]-2,2-di­methyl­propanamide n-hexane 0.25-solvate hemihydrate

2013

The asymmetric unit of the title compound, C14H22N4O2·0.25C6H14·0.5H2O, contains two independent molecules of 2,4-bis(pivaloylamino)pyrimidine (M) with similar conformations, one water molecule and one-halfn-hexane solvent molecule situated on an inversion center. In one independentMmolecule, one of the twotert-butyl groups is rotationally disordered between two orientations in a 3:2 ratio. Then-hexane solvent molecule is disordered between two conformations in the same ratio. The water molecule bridges two independentMmoleculesviaO—H...O, N—H...O and O—H...N hydrogen bonds into a 2M·H2O unit, and these units are further linked by N—H...N hydrogen bonds into chains running in the [010] dire…

CrystallographyHydrogen bondHemihydrateGeneral Chemistrydata-to-parameter ratio = 14.2T = 123 KR factor = 0.079Condensed Matter PhysicsBioinformaticsPropanamideOrganic PapersSolventHexaneCrystallographychemistry.chemical_compoundwR factor = 0.164chemistryQD901-999mean σ(C–C) = 0.006 Åsingle-crystal X-ray studyGeneral Materials Scienceta116disorder in main residue
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Novel σ1 antagonists designed for tumor therapy: Structure – activity relationships of aminoethyl substituted cyclohexanes

2021

Abstract Depending on the substitution pattern and stereochemistry, 1,3-dioxanes 1 with an aminoethyl moiety in 4-position represent potent σ1 receptor antagonists. In order to increase the stability, a cyclohexane ring first replaced the acetalic 1, 3-dioxane ring of 1. A large set of aminoethyl substituted cyclohexane derivatives was prepared in a six-step synthesis. All enantiomers and diastereomers were separated by chiral HPLC at the stage of the primary alcohol 7, and their absolute configuration was determined by CD spectroscopy. Neither the relative nor the absolute configuration had a large impact on the σ1 affinity. The highest σ1 affinity was found for cis-configured benzylamines…

DU145 tumor cellsCachannelPrimary alcohol01 natural sciencesAminoethylcyclohexanes; Antagonistic activity; Biotransformation; Ca; 2+; influx assay; Calculated free energy of binding; CD spectroscopy; Chiral HPLC; DU145 tumor cells; Inhibition of human prostate tumor cell growth; Lipophilicity; Molecular dynamics simulations; Molecular interactions; per-residue binding free energy; Selectivity; Stereochemistry; Structure affinity relationships; Voltage gated Ca; 2+; channel; σ receptors; σ; 1; receptor affinityInhibition of human prostate tumor cell growthStereochemistryDrug DiscoveryMoietySelectivityBiotransformationσ receptor0303 health sciencesChemistryAminoethylcyclohexanesCD spectroscopyAbsolute configurationAminoethylcyclohexaneMolecular interactionGeneral MedicineAntagonistic activityper-residue binding free energyreceptor affinityLipophilicityVoltage gated CaStereochemistry12+Calculated free energy of bindingRetinal ganglion03 medical and health sciencesσMolecular dynamics simulationChiral HPLCLipophilicityMolecular interactionsStructure affinity relationship030304 developmental biologyPharmacologyDU145 tumor cellinflux assayMolecular dynamics simulations010405 organic chemistryOrganic ChemistryDiastereomer0104 chemical sciencesChiral column chromatographyσ receptorsStructure affinity relationshipsEnantiomerEuropean Journal of Medicinal Chemistry
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LA DOPPIA CITAZIONE DEL FR. 964 DI EURIPIDE NEL DE INDOLENTIA DI GALENO

2013

The purpose of this study is to demonstrate that the second quotation of the Euripidean fr. 964 N 2 in the De indolentia, a Galenic treatise recently saved from oblivion thanks to Antoine Pietrobelli, is in fact an interpolation due to the enterprise of a scribe. The argumentation is based on words coming immediately before and after the presumed quotation.

De indolentia Galien fr. 964 N 2 di Euripide ἀλυπίας.
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Measure and dimension functions: measurability and densities

1997

During the past several years, new types of geometric measure and dimension have been introduced; the packing measure and dimension, see [Su], [Tr] and [TT1]. These notions are playing an increasingly prevalent role in various aspects of dynamics and measure theory. Packing measure is a sort of dual of Hausdorff measure in that it is defined in terms of packings rather than coverings. However, in contrast to Hausdorff measure, the usual definition of packing measure requires two limiting procedures, first the construction of a premeasure and then a second standard limiting process to obtain the measure. This makes packing measure somewhat delicate to deal with. The question arises as to whe…

Discrete mathematicsPacking dimensionGeneral MathematicsHausdorff dimensionDimension functionOuter measureHausdorff measureEffective dimensionσ-finite measureBorel measureMathematicsMathematical Proceedings of the Cambridge Philosophical Society
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A note on the distance set problem in the plane

2001

We use a simple geometric-combinatorial argument to establish a quantitative relation between the generalized Hausdorff measure of a set and its distance set, extending a result originally due to Falconer.

Discrete mathematicsPlane (geometry)Applied MathematicsGeneral MathematicsMathematical analysisσ-finite measureMeasure (mathematics)Set (abstract data type)Simple (abstract algebra)Mathematics::Metric GeometryHausdorff measureOuter measureBorel measureMathematicsProceedings of the American Mathematical Society
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On the conical density properties of measures on $\mathbb{R}^n$

2005

We compare conical density properties and spherical density properties for general Borel measures on $\mathbb{R}^n$ . As a consequence, we obtain results for packing and Hausdorff measures $\mathcal{P}_h$ and $\mathcal{H}_h$ provided that the gauge function $h$ satisfies certain conditions. One consequence of our general results is the following: let $m, n\,{\in}\,\mathbb{N}, 0\,{\lt}\,s\,{\lt}\,m\,{\leq}\,n$ , $0\,{\lt}\,\eta\,{\lt}\,1$ , and suppose that $V$ is an $m$ -dimensional linear subspace of $\mathbb{R}^n$ . Let $\mu$ be either the $s$ -dimensional Hausdorff measure or the $s$ -dimensional packing measure restricted to a set $A$ with $\mu(A)\,{\lt}\,\infty$ . Then for $\mu$ -almos…

Discrete mathematicsRandom measureGeneral MathematicsDimension functionOuter measureHausdorff measureBorel setσ-finite measureBorel measureLinear subspaceMathematicsMathematical Proceedings of the Cambridge Philosophical Society
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Orlicz–Sobolev extensions and measure density condition

2010

Abstract We study the extension properties of Orlicz–Sobolev functions both in Euclidean spaces and in metric measure spaces equipped with a doubling measure. We show that a set E ⊂ R satisfying a measure density condition admits a bounded linear extension operator from the trace space W 1 , Ψ ( R n ) | E to W 1 , Ψ ( R n ) . Then we show that a domain, in which the Sobolev embedding theorem or a Poincare-type inequality holds, satisfies the measure density condition. It follows that the existence of a bounded, possibly non-linear extension operator or even the surjectivity of the trace operator implies the measure density condition and hence the existence of a bounded linear extension oper…

Discrete mathematicsTransverse measureComplete measureApplied MathematicsBounded functionComplex measureσ-finite measureMeasure (mathematics)AnalysisSobolev inequalityTrace operatorMathematicsJournal of Mathematical Analysis and Applications
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Carga global, regional y nacional de neurológicas. Desórdenes, 1990-2016: un análisis sistemático para el Global Estudio de la carga de enfermedad 20…

2019

Publisher´s version (útgefin grein).

DánarmeinMaleEpidemiologyDiseasesMalalties cerebralsGlobal Burden of DiseaseDisability Evaluation0302 clinical medicineCase fatality ratePsychologyKonurCause of deathAged 80 and overeducation.field_of_studyIncidenceMenTaugavísindiddc:3. Good healthSálfræðiWorld healthMuerteNeurologyGBD 2016 Neurology CollaboratorsBrain diseasesQuality-Adjusted Life YearsAlzheimer diseaseCarga global de enfermedadesNervous systemmedicine.medical_specialtyGlobal burden of diseasesLífsgæðiArticle03 medical and health sciencesHealth SciencesHumansWomeneducationTrastornos neurológicosVLAGAgedScience & Technology3112 NeurosciencesGlobal Burden of Diseases030104 developmental biologyYears of potential life lostΕπιστήμες ΥγείαςDementiaHuman medicineNeurosciences & NeurologyNeurology (clinical)Clinical Medicine1109 NeurosciencesNeurological disorders030217 neurology & neurosurgerydementiaRC0301 basic medicinePediatricsDánartíðniNutrition and Disease3124 Neurology and psychiatryDisease StudyTaugasjúkdómarRisk FactorsVoeding en ZiekteCause of DeathGlobal healthPrevalenceNeurological disorders; Global Burden of DiseasesCauses of deathPublic healthMortality rateMental DisordersAge FactorsPublic Health Global Health Social Medicine and EpidemiologyMiddle Agedneurologic diseaseDeathLýðheilsaFemaleLife Sciences & BiomedicineQuality of lifeAdultPopulationClinical NeurologySex FactorsmedicineLife ScienceDisability-adjusted life year:Medicine [Science]MortalityPsychiatryDisease burdenNeurology & Neurosurgeryburden of neurological disordersFaraldsfræðibusiness.industryKlinisk medicinCauses de la mort1103 Clinical SciencesFolkhälsovetenskap global hälsa socialmedicin och epidemiologiSocioeconomic FactorsKarlarglobal disease burdenNervous System DiseasesCause of death/trendsbusiness
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Le comportement du soufre et les conditions d'oxydoréduction dans les basaltes hydratés de l'Etna inférés par des inclusions vitreuses et des verres …

2017

Sulfur is an important volatile component of magmas that presents different oxidation states, depending on the redox conditions and on the phase of occurrence: in silicate melts it is typically dissolved as S⁶⁺ and/or S²⁻ , in the gas phase it occurs principally as SO₂ (S⁴⁺ ) and H₂S (S²⁻). Mount Etna, in which magmatic redox conditions are poorly constrained, is used as a case study to investigate sulfur behavior in hydrous basaltic magmas during magma differentiation and degassing. This research integrates the study of natural olivine-hosted melt inclusions with an experimental study on S solubility in hydrous alkali basalts at magmatic conditions.Experimental results suggest the importan…

ExpériencesInclusions vitreuses silicatiquesSoufreSettore GEO/07 - Petrologia E Petrografia[SDU.STU]Sciences of the Universe [physics]/Earth Sciencesoxygen fugacitysilicate melt inclusionsexperimentsXANES Fe3+/ΣFe ratiosulfur silicate melt inclusions experiments XANES Fe3+/ΣFe ratio oxygen fugacityXANES Fe³⁺/ΣFe ratioSilicate melt inclusionssulfurFugacité d'oxygèneExperimentsSulfurOxygen fugacity
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