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Functional characterization of circulating tumor cells (CTCs) from metastatic ER+/HER2− breast cancer reveals dependence on HER2 and FOXM1 for endocr…
2021
Simple Summary Acquired endocrine resistance and late recurrence in patients with ER+/HER2− breast cancer are complex and not fully understood. Here, we evaluated mechanisms of acquired resistance in circulating tumor cells (CTCs) from an ER+/HER2− breast cancer patient who initially responded but later progressed under endocrine treatment. We found a switch from ERα-dependent to HER2-dependent and ERα-independent expression of FOXM1, which may enable disseminated ER+/HER2− cells to re-initiate tumor cell growth and metastasis formation in the presence of endocrine treatment. We found that NFkB signaling sustains HER2 and FOXM1 expression in CTCs in the presence of ERα inhibitors suggesting…
Observation of e + e − → ηψ(2S) at center-of-mass energies from 4.236 to 4.600 GeV
2021
Journal of high energy physics 2021(10), 177 (2021). doi:10.1007/JHEP10(2021)177
Regards documentaires sur la recherche francophone iranienne et perspectives pour Synergies Iran: de l'orientalisme au verbo-tonalisme
2020
C���est en portant nos regards sur le paysage ��ditorial francophone iranien directement visible en ligne que nous saluons la fondation de la revue Synergies Iran et la parution, en 2020, de son premier num��ro. Cette d��marche s���effectue dans un premier temps de fa��on globale, dans le but de rassembler des institutions et associations qui ��uvrent, chacune �� sa mani��re, depuis la 2�� moiti�� du XXe si��cle, pour la diffusion des ��tudes iraniennes. Puis dans un second temps, la d��marche se pr��cise afin de sonder les contenus scientifiques iraniens pr��sents sur le R��seau des publications du GERFLINT, Groupe d�����tudes et de recherches pour le fran��ais langue internationale fond��…
Quatre recueils d'articles
2020
Ce num��ro 28 de la revue Synergies Alg��rie contient les d��finitions liminaires de multi et de pluri en didactologie/didactique des langues-cultures et didactique de la langue-culture fran��aise, deux concepts vieux comme le monde : Le multi, c���est la quantit�� ; le pluri, encore et toujours, depuis Saussure et Bally��� et d���autres ��� c���est la diff��rence. (���) Avec le multi et le nombre, on est dans la connaissance d��notative (l���organisation grammaticale et lexicale, par exemple (���) ; avec le pluri, on plonge dans l���infini, dans le gouffre rimbaldien du sens, dans les variations connotatives, l���interpr��tation, la traduction��� (Jacques Cort��s, Pr��face). Ces d��finitio…
Primeros hallazgos del molusco marino invasor Pinctada radiata (Leach, 1840) (Bivalvia: F. Margaritidae) en la costa valenciana (España)
2021
Se dan a conocer por primera vez diversos hallazgos del molusco bivalvo marino lessepsiano Pinctada radiata en la costa valenciana, concretamente en la costa del Golfo de Valencia (España). Esta especie puede causar efectos negativos sobre el ecosistema, afectando a su biodiversidad autóctona. Se proporcionan datos conquiológicos de la concha y el mapa de distribución geográfica actual de esta especie en la costa valenciana y en el mediterráneo occidental. -- First findings of invasive marine mollusc Pinctada radiata (Leach, 1840) (Bivalvia: F. Margaritidae) on the Valencian coast (Spain). Several findings of the marine Lessepsian bivalve mollusc Pinctada radiata are disclosed for the first…
Breast Cancer Patients' Fear of Treatment: Results from the Multicenter Longitudinal Study BRENDA II.
2015
Background: Fear of cancer treatment can become overwhelming. It is important to understand what patients are mainly afraid of and what factors are correlated with intense fear of treatment. Methods: Patients with primary breast cancer (n = 761) completed questionnaires about fear of treatment before surgery (t1), and before (t2) and after (t3) adjuvant treatment. Psychological co-morbidity was assessed using the Patient Health Questionnaire. Logistic regression identified predictors of intense fear of treatment. Results: Patients were most afraid of chemotherapy (mean score 3.5), and fear remained high throughout follow-up; fear of radiotherapy and of surgery was lower and decreased over t…
Programs' Efficacy to Develop Employable Skills for People With Functional Diversity: A Meta-Analysis
2021
Purpose: Promoting the labour integration of people with functional diversity is a key element to achieve their social inclusion. This meta-analysis aims to examine the effectiveness of experimental programs in developing employable skills for people with disabilities. Methods: Literature searches up to June 2019 were conducted in four databases (Web of Science, Scopus, PsycINFO and ERIC). Studies that met the following criteria were selected: (1) The program should develop employable skills; (2) the participants should be people with functional diversity; (3) the study should have a design with an experimental group and a control group as well as pretest and posttest measurements; (4) the …
International Vocational Education and Training Research: An Introduction to the Special Issue
2021
The seven articles in this special issue represent a wide range of international comparative and review studies by international research teams from China, Germany, India, Russia, Switzerland and Mexico. The presented projects are part of the national program "Research on the Internationalisation of Vocational Education and Training", funded by the German Federal Ministry of Education and Research (BMBF). An adapted version of Urie Bronfenbrenner���s ecological systems theory forms the conceptual framework of the special issue. The four system levels (micro, meso, exo and macro) are addressed by one article each. The article on the microsystem level focuses on the intended and implemented c…
Sukupuoli ja subjektius sosiaalityössä : tulkintoja naistyöntekijöiden muistoista
2005
"Table 41: figure 5 supplemental" of "Production of $\pi^0$ and $\eta$ mesons in Cu$+$Au collisions at $\sqrt{s_{_{NN}}}$=200 GeV"
2021
$\eta$ $R_{AB}$ supplemental to figure 5 from 60-90% peripheral Cu+Au collisions. Type A uncertainties are uncorrelated point-to-point. Type B uncertainties are correlated point-to-point. Type C uncertainties affect the scale of the data.