0000000000001727

AUTHOR

Longevo-sca Registry Investigators

showing 4 related works from this author

Frequency of Renal Dysfunction and Frailty in Patients ≥80 Years of Age With Acute Coronary Syndromes.

2019

While a significant association between renal function and outcomes in patients with acute coronary syndromes (ACS) has been consistently described, little information exists about the magnitude of this association in patients at older ages. No study assessed the prognostic role of renal function according to frailty in patients with ACS. The LONGEVO-SCA registry included unselected ACS patients aged≥80 years. Frailty was asessesed by the FRAIL scale, and baseline creatinine clearance was calculated by the Cockroff-Gault formula. We evaluated the impact of renal function on mortality or readmission at 6-months according to frailty status by the Cox regression method. A total of 473 patients…

Malemedicine.medical_specialtyFrail ElderlyRenal function030204 cardiovascular system & hematology03 medical and health sciences0302 clinical medicineInternal medicinemedicineHumansIn patient030212 general & internal medicineProspective StudiesRegistriesAcute Coronary SyndromeProspective cohort studyGeriatric AssessmentAged 80 and overFrailtyProportional hazards modelbusiness.industryRiñonesMean ageEnfermedadesMulticenter studySpainMortalidadCardiologyObservational studyFemaleKidney DiseasesCardiology and Cardiovascular MedicinebusinessEnfermedadGlomerular Filtration RateThe American journal of cardiology
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Prognostic impact of anemia according to frailty status in elderly patients with acute coronary syndromes.

2019

Aims Anemia is associated with poorer outcomes in patients with acute coronary syndromes (ACS), but the magnitude of this association in elderly patients remains poorly understood. No study has assessed the prognostic impact of anemia according to frailty status in this setting. Methods The LONGEVO-SCA registry included unselected ACS patients aged at least 80 years. A geriatric assessment was performed during hospitalization, including frailty assessment using the FRAIL scale. Anemia was defined by the WHO criteria. We evaluated the impact of anemia on 6-month mortality according to the presence of frailty. Results A total of 517 patients were assessed. Mean age was 84.3 years, and a total…

Malemedicine.medical_specialtyAgingTime FactorsAnemiaFrail Elderly030204 cardiovascular system & hematologyRisk Assessment03 medical and health sciences0302 clinical medicinePredictive Value of TestsRisk Factorshemic and lymphatic diseasesInternal medicinemedicineHumans030212 general & internal medicineProspective StudiesRegistriesAcute Coronary SyndromeProspective cohort studyGeriatric AssessmentAged 80 and overFrailtybusiness.industryIncidence (epidemiology)IncidenceHazard ratioAge FactorsAnemiaGeneral Medicinemedicine.diseasePrognosisSpainPredictive value of testsCohortObservational studyFemaleCardiology and Cardiovascular MedicineRisk assessmentbusinessJournal of cardiovascular medicine (Hagerstown, Md.)
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Impact of frailty and atrial fibrillation in elderly patients with acute coronary syndromes

2021

Background: There is scarce information on the prognostic role of frailty and Atrial Fibrillation (AF) in elderly patients Acute Coronary Syndrome (ACS). Methods: The aim was to analyse the management of elderly patients with frailty and AF who suffered an ACS using data of the prospective multicentre LONGEVO-SCA registry. We evaluated the predictive performance of FRAIL, Charlson scores and AF status for adverse events at 6 months follow-up. Results: A total of 531 unselected patients with ACS and above 80 years old [mean age 84.4 (SD=3.6) years; 322 (60.6%) male] were enrolled, of whom 128 (24.1%) with AF and 145 (27.3%) with frailty. Mutually exclusive number of patients were as follows:…

MaleAcute coronary syndromemedicine.medical_specialtyEnfermedad cardiovascularAncianoClinical BiochemistryCharlson indexComorbidity030204 cardiovascular system & hematologyMutually exclusive eventsPatient ReadmissionSeverity of Illness IndexBiochemistry03 medical and health sciences0302 clinical medicineInternal medicineAtrial FibrillationDiabetes MellitusMyocardial RevascularizationmedicineHumansCognitive DysfunctionSinus rhythm030212 general & internal medicineAcute Coronary SyndromeMortalityAdverse effectAnciano frágilAgedProportional Hazards ModelsAged 80 and overHeart FailureFibrilación atrialFrailtybusiness.industryInsuficiencia cardíacaAtrial fibrillationMean ageGeneral Medicinemedicine.diseaseStrokeFunctional StatusCardiovascular DiseasesCardiologyFemaleFunctional statusbusinessEuropean Journal of Clinical Investigation
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Baseline CHA 2 DS 2 ‐VASc score and prognosis in octogenarians with non‐ST segment elevation acute coronary syndrome

2021

Background CHA2DS2-VASc Score is widely used to predict thromboembolic risk in patients with Atrial Fibrillation (AF). We sought to study if this score predicts outcomes in elderly patients with Non-ST segment Elevation Acute Coronary Syndromes (NSTEACS). Methods The multicenter LONGEVO-SCA prospective registry included 532 unselected patients with NSTEACS aged ≥80 years. Data to calculate CHA2DS2-VASc Score were available in 523 patients (98.3%). They were classified according to CHA2DS2-VASc Score: group 1 (score ≤ 4), and 2 (5-9). We studied outcomes in terms of mortality or readmission at 6 months follow-up. Results A total of 266 patients (51%) had a high CHA2DS2-VASc Score (group 2). …

Acute coronary syndromemedicine.medical_specialtyEjection fractionbusiness.industryGerontologíaEnfermedad cardiovascularAtrial fibrillationGeneral Medicinemedicine.diseaseHeart failureInternal medicineCHA2DS2–VASc scoremedicineCardiologyST segmentSíndrome coronario agudoInfarto de miocardiobusinessStrokeKillip classInternational Journal of Clinical Practice
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