0000000000002248

AUTHOR

Pierluigi Benedetti Panici

showing 5 related works from this author

Histologic analysis of specimens from laparoscopic endometrioma excision performed by different surgeons: does the surgeon matter?

2011

Objective To evaluate whether the amount of ovarian tissue inadvertently removed along with the endometrioma cyst wall at laparoscopy differs in relation to the operating surgeon's level of expertise. Design Multicenter, prospective trial. Setting Four tertiary care university hospitals. Patient(s) Fifty patients, aged 25 to 40 years, with monolateral ovarian endometriomas who underwent laparoscopic excision. Intervention(s) Operation with the stripping technique by surgeons with specific expertise in endometriosis surgery in four centers (groups A, B, C, and D) and by residents with average training in laparoscopic surgery (group E). Main Outcome Measure(s) Histologic examination for the e…

endometriosisLaparoscopic surgerymedicine.medical_treatmentEndometriosisEndometriosis laparoscopy ovarian cystsGynecologic Surgical Proceduresmorphologyovarian endometriomaMedicineSingle-Blind MethodOvarian DiseasesLaparoscopyclinical articleresidency educationmedicine.diagnostic_testmedical specialistarticleObstetrics and Gynecologyendometriosis; laparoscopy; ovarian cystsOrgan Sizelaparoscopic surgeryTumor Burdenendometrium tumorfemaleuterus surgerymedicine.anatomical_structurepriority journalstripping techniquehistopathologyClinical CompetenceAdultmedicine.medical_specialtyOvaryPhysiciansHumanshumanOvarian cystbusiness.industryOvaryHistologymedicine.diseasehuman tissuethicknessSurgeryEndoscopyadult; article; clinical article; endometriosis; endometrium tumor; female; histopathology; human; human tissue; laparoscopic surgery; medical specialist; morphology; multicenter study; ovarian endometrioma; ovary; priority journal; residency education; stripping technique; surgeon; thickness; uterus surgery Adult; Clinical Competence; Endometriosis; Female; Gynecologic Surgical Procedures; Humans; Laparoscopy; Organ Size; Ovarian Diseases; Ovary; Physicians; Single-Blind Method; Tumor Burdenmulticenter studySettore MED/40 - GINECOLOGIA E OSTETRICIAReproductive MedicinesurgeonLaparoscopyHistopathologybusiness
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Escalating doses of paclitaxel and epirubicin in combination with cisplatin in advanced ovarian epithelial carcinoma: a phase I–II study

2003

Our objective was to identify a new active three-drug combination regimen consisting of paclitaxel (PTX), epirubicin (EPI) and cisplatin as first-line line chemotherapy for advanced ovarian carcinoma. A phase I study was carried out to evaluate the dose-limiting toxicity (DLT) and the maximally tolerated dose (MTD) of PXT and EPI in combination with a fixed dose of cisplatin every 4 weeks. Side-effects were recorded according to the NCI Common Toxicity Criteria. Patients were treated in cohorts of three with fixed-dose cisplatin 80 mg/m 2 and EPI 80 → 100 mg/ m 2 and PXT 100 → 160 mg/m 2 until DLT was reached. Once MTD was identified, a single-step phase II study was therefore carried out t…

AdultMaleCancer Researchmedicine.medical_specialtyAdolescentPaclitaxelmedicine.medical_treatmentUrologyPhases of clinical researchAntineoplastic AgentsPharmacologyAntineoplastic Combined Chemotherapy ProtocolsMucositisHumansMedicinePharmacology (medical)AgedEpirubicinNeoplasm StagingOvarian NeoplasmsPharmacologyCisplatinChemotherapyAntibiotics AntineoplasticDose-Response Relationship Drugbusiness.industryCarcinomaMiddle Agedmedicine.diseaseAntineoplastic Agents PhytogenicSurvival AnalysisRegimenOncologyToxicityAntiemeticsFemaleCisplatinbusinessFebrile neutropeniamedicine.drugEpirubicinAnti-Cancer Drugs
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Risk factors associated with adverse fetal outcomes in pregnancies affected by Coronavirus disease 2019 (COVID-19): a secondary analysis of the WAPM …

2020

Abstract Objectives To evaluate the strength of association between maternal and pregnancy characteristics and the risk of adverse perinatal outcomes in pregnancies with laboratory confirmed COVID-19. Methods Secondary analysis of a multinational, cohort study on all consecutive pregnant women with laboratory-confirmed COVID-19 from February 1, 2020 to April 30, 2020 from 73 centers from 22 different countries. A confirmed case of COVID-19 was defined as a positive result on real-time reverse-transcriptase-polymerase-chain-reaction (RT-PCR) assay of nasal and pharyngeal swab specimens. The primary outcome was a composite adverse fetal outcome, defined as the presence of either abortion (pre…

COVID-19 VaccineInfectious Disease TransmissionPerinatal DeathAbortionClinical Laboratory TechniqueMiscarriageCohort Studies0302 clinical medicineCOVID-19 TestingPregnancyRisk Factors3123 Gynaecology and paediatricsSecondary analysisPerinatal medicineAbortion SpontaneouMedicineVertical030212 general & internal medicineViralPregnancy Complications Infectiouscoronavirus; perinatal morbidity; perinatal mortality; covid-19Coronavirus; perinatal morbidity; perinatal mortality; Abortion Spontaneous; COVID-19; COVID-19 Testing; COVID-19 Vaccines; Clinical Laboratory Techniques; Cohort Studies; Coronavirus Infections; Female; Gestational Age; Humans; Infant Newborn; Infant Premature; Infectious Disease Transmission Vertical; Pandemics; Pneumonia Viral; Pregnancy; Pregnancy Complications Infectious; Pregnancy Outcome; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; SARS-CoV-2; Betacoronavirus; Fetal Death; Perinatal Deathperinatal morbidity030219 obstetrics & reproductive medicineObstetricsReverse Transcriptase Polymerase Chain ReactionInfectiousPregnancy OutcomeGestational ageObstetrics and Gynecology3. Good healthSettore MED/40perinatal mortalityGestationFemaleCoronavirus InfectionsInfant PrematureHumanmedicine.medical_specialtyCOVID-19 VaccinesCoronavirus disease 2019 (COVID-19)CoronaviruPneumonia ViralSocio-culturaleGestational AgeIntrauterine deviceCoronavirus; perinatal morbidity; perinatal mortality03 medical and health sciencesBetacoronavirusPARVOVIRUS B19 INFECTIONCoronavirus perinatal morbidity perinatal mortalityHumansAdverse effectPrematurePandemicsFetal DeathPregnancyFetusBetacoronaviruPandemicCoronavirus Infectionbusiness.industryClinical Laboratory TechniquesSARS-CoV-2Risk FactorSpontaneousMORTALITYInfant NewbornAbortionCOVID-19InfantOdds ratioPneumoniamedicine.diseaseNewbornInfectious Disease Transmission VerticalAbortion SpontaneousPregnancy ComplicationsCoronavirusPediatrics Perinatology and Child HealthPregnancy Complications InfectiouCohort StudiebusinessCoronavirus; perinatal mortality; perinatal morbidityJournal of perinatal medicine
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Impact of covid-19 in gynecologic oncology: A nationwide italian survey of the sigo and mito groups

2020

Objective Coronavirus disease 2019 (COVID-19) has caused rapid and drastic changes in cancer management. The Italian Society of Gynecology and Obstetrics (SIGO), and the Multicenter Italian Trials in Ovarian cancer and gynecologic malignancies (MITO) promoted a national survey aiming to evaluate the impact of COVID-19 on clinical activity of gynecologist oncologists and to assess the implementation of containment measures against COVID-19 diffusion. Methods The survey consisted of a self-administered, anonymous, online questionnaire. The survey was sent via email to all the members of the SIGO, and MITO groups on April 7, 2020, and was closed on April 20, 2020. Results Overall, 604 particip…

International CooperationComputer-assisted web interviewingCOVID-19; Health Care Surveys; SARS-CoV-2 Infection; Surgical Oncology; Betacoronavirus; COVID-19; Coronavirus Infections; Female; Genital Neoplasms Female; Gynecologic Surgical Procedures; Gynecology; Humans; Infection Control; International Cooperation; Italy; Medical Oncology; Pandemics; Pneumonia Viral; SARS-CoV-2; Societies Medical; Surveys and Questionnaires; TriageMedical Oncology0302 clinical medicineGynecologic Surgical ProceduresSurgical oncologyGynecologic Surgical ProcedureSurveys and QuestionnairesPandemicHealth careMedicineInfection controlViralStatistics & numerical dataSurveySocieties Medical030219 obstetrics & reproductive medicineObstetrics and GynecologyGeneral MedicineSurgical OncologyOncologyItaly030220 oncology & carcinogenesisSARS-CoV-2 InfectionOriginal ArticleFemaleGenital NeoplasmsCoronavirus Infectionsmedicine.medical_specialtyGenital Neoplasms FemalePneumonia ViralGynecologic oncology03 medical and health sciencesBetacoronavirusMedicalHumansCOVID-19; Health Care Surveys; SARS-CoV-2 Infection; Surgical OncologyPandemicsInfection ControlBetacoronaviruPandemicbusiness.industryCoronavirus InfectionSARS-CoV-2COVID-19PneumoniaTriageSettore MED/40 - GINECOLOGIA E OSTETRICIAHealth Care SurveyGynecologyFamily medicineHealth Care SurveysTriagebusinessSocieties
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Characteristics and patterns of care of endometrial cancer before and during COVID-19 pandemic

2021

Objective Coronavirus disease 2019 (COVID-19) outbreak has correlated with the disruption of screening activities and diagnostic assessments. Endometrial cancer (EC) is one of the most common gynecological malignancies and it is often detected at an early stage, because it frequently produces symptoms. Here, we aim to investigate the impact of COVID-19 outbreak on patterns of presentation and treatment of EC patients. Methods This is a retrospective study involving 54 centers in Italy. We evaluated patterns of presentation and treatment of EC patients before (period 1: March 1, 2019 to February 29, 2020) and during (period 2: April 1, 2020 to March 31, 2021) the COVID-19 outbreak. Results M…

medicine.medical_specialtyendometrial neoplasmsCoronavirus disease 2019 (COVID-19)Endometrial Cancer; COVID-19; Uterine cancer; SARS-CoV-2covid-19; endometrial cancer; sars-cov-2; uterine cancer; female; humans; pandemics; retrospective studies; sars-cov-2; covid-19; endometrial neoplasmspandemicsEndometrial CancerNOCOVID-19; Endometrial Cancer; SARS-CoV-2; Uterine cancerRetrospective StudiePandemicmedicineUterine cancerhumansPatterns of carePandemicObstetricsbusiness.industrySARS-CoV-2Endometrial cancerObstetrics and GynecologyCOVID-19General Medicinemedicine.diseaseEndometrial Neoplasmsretrospective studiesSettore MED/40 - GINECOLOGIA E OSTETRICIAfemaleOncologyOriginal ArticleFemalebusinessHuman
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