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RESEARCH PRODUCT
Characteristics and patterns of care of endometrial cancer before and during COVID-19 pandemic
Giorgio BoganiGiovanni ScambiaChiara CimminoFrancesco FanfaniBarbara CostantiniMatteo LoverroGabriella FerrandinaFabio LandoniLuca BazzuriniTommaso GrassiDomenico VitobelloGabriele SiestoAnna Myriam PerroneVanna ZanagnoloPierandrea De IacoFrancesco MultinuFabio GhezziJvan CasarinRoberto BerrettaVito A CapozziErrico ZupiGabriele CentiniAntonio PellegrinoSilvia CorsoGuido StevenazziSerena MontoliAnna Chiara BoschiGiuseppe ComerciPantaleo GrecoRuby MartinelloFrancesco SopracordevoleGiorgio GiordaTommaso SimonciniMarta CarettoEnrico SartoriFederico FerrariAntonio CianciGiuseppe SarpietroMaria Grazia MatarazzoFulvio ZulloGiuseppe BifulcoMichele MorelliAnnamaria FerreroNicoletta BigliaFabio BarraSimone FerreroUmberto Leone Roberti MaggioreStefano CianciVito ChianteraAlfredo ErcoliGiulio SozziAngela MartocciaSergio SchettiniTeresa OrlandoFrancesco G CannoneGiuseppe EttoreAndrea PuppoMartina BorgheseCanio MartinelliLudovico MuziiViolante Di DonatoLorenza DriulStefano RestainoAlice BergaminiGiorgio CandottiLuca BoccioloneFrancesco PlottiRoberto AngioliGiulia MantovaniMarcello CeccaroniChiara CassaniMattia DominoniLaura GiambancoSilvia AmodeoLivio LeoRaphael ThomassetDiego RaimondoRenato SeracchioliMario MalzoniFranco GorleroMartina Di LucaEnrico BusatoSami KilzieAndrea Dell'acquaGiovanna ScarfonePaolo VercelliniMarco PetrilloSalvatore DessoleGiampiero CapobiancoAndrea CiavattiniGiovanni Delli CarpiniLuca GiannellaLiliana MereuSaverio TateoFlavia SorbiMassimiliano FambriniStefania CicognaFederico RomanoGiuseppe RicciGiuseppe TrojanoRoberto ConsonniSimona CantaluppiAntonio LippolisRaffaele TinelliGiovanni D'ippolitoLorenzo AguzzoliVincenzo D MandatoStefano PalombaDavide CalandraMaurizio RosatiCinzia GalloDaniela SuricoValentino RemorgidaFrancesco RuscittoPaolo BerettaPierluigi Benedetti PaniciFrancesco Raspagliesisubject
medicine.medical_specialtyendometrial neoplasmsCoronavirus disease 2019 (COVID-19)Endometrial Cancer; COVID-19; Uterine cancer; SARS-CoV-2covid-19; endometrial cancer; sars-cov-2; uterine cancer; female; humans; pandemics; retrospective studies; sars-cov-2; covid-19; endometrial neoplasmspandemicsEndometrial CancerNOCOVID-19; Endometrial Cancer; SARS-CoV-2; Uterine cancerRetrospective StudiePandemicmedicineUterine cancerhumansPatterns of carePandemicObstetricsbusiness.industrySARS-CoV-2Endometrial cancerObstetrics and GynecologyCOVID-19General Medicinemedicine.diseaseEndometrial Neoplasmsretrospective studiesSettore MED/40 - GINECOLOGIA E OSTETRICIAfemaleOncologyOriginal ArticleFemalebusinessHumandescription
Objective Coronavirus disease 2019 (COVID-19) outbreak has correlated with the disruption of screening activities and diagnostic assessments. Endometrial cancer (EC) is one of the most common gynecological malignancies and it is often detected at an early stage, because it frequently produces symptoms. Here, we aim to investigate the impact of COVID-19 outbreak on patterns of presentation and treatment of EC patients. Methods This is a retrospective study involving 54 centers in Italy. We evaluated patterns of presentation and treatment of EC patients before (period 1: March 1, 2019 to February 29, 2020) and during (period 2: April 1, 2020 to March 31, 2021) the COVID-19 outbreak. Results Medical records of 5,164 EC patients have been retrieved: 2,718 and 2,446 women treated in period 1 and period 2, respectively. Surgery was the mainstay of treatment in both periods (p=0.356). Nodal assessment was omitted in 689 (27.3%) and 484 (21.2%) patients treated in period 1 and 2, respectively (p<0.001). While, the prevalence of patients undergoing sentinel node mapping (with or without backup lymphadenectomy) has increased during the COVID-19 pandemic (46.7% in period 1 vs. 52.8% in period 2; p<0.001). Overall, 1,280 (50.4%) and 1,021 (44.7%) patients had no adjuvant therapy in period 1 and 2, respectively (p<0.001). Adjuvant therapy use has increased during COVID-19 pandemic (p<0.001). Conclusion Our data suggest that the COVID-19 pandemic had a significant impact on the characteristics and patterns of care of EC patients. These findings highlight the need to implement healthcare services during the pandemic.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2021-08-31 |