0000000000007247

AUTHOR

Sophie Pecquet

showing 4 related works from this author

Growth and safety evaluation of infant formulae containing oligosaccharides derived from bovine milk: a randomized, double-blind, noninferiority trial

2014

A limited number of nondigestible oligosaccharides are available for use in infant formula. This study evaluated growth and safety in infants fed formula supplemented with a mixture of bovine milk-derived oligosaccharides (BMOS). This mixture, which was generated from whey permeate, contains galactooligosaccharides and other oligosaccharides from bovine milk, such as 3′- and 6′-sialyllactose. We hypothesized that growth in infants fed BMOS-supplemented formula would be noninferior to that in infants fed standard formula. Healthy term infants ≤14 days old were randomly assigned to standard formula (control; n = 84); standard formula with BMOS (IF-BMOS; n = 99); or standard formula with BMOS …

Malemedicine.medical_specialtyPediatricsBifidobacterium longumOligosaccharidesGrowthWeight GainGastroenterologyInfant nutritionFecesChild DevelopmentLactobacillus rhamnosusDouble-Blind MethodInternal medicinemedicineAnimalsHumansPediatrics Perinatology and Child HealthGastrointestinal TransitFecesHealthy infantsbiologyAnthropometrybusiness.industryProbioticsInfant NewbornInfantbiology.organism_classificationConfidence intervalInfant FormulaMilkInfant formulaPediatrics Perinatology and Child HealthFood FortifiedVomitingCattleFemalemedicine.symptombusinessFlatulenceWeight gainBovine milk-derived oligosaccharidesResearch ArticleBMC Pediatrics
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Safety and Tolerance Evaluation of Milk Fat Globule Membrane-Enriched Infant Formulas: A Randomized Controlled Multicenter Non-Inferiority Trial in H…

2014

ObjectiveThis multicenter non-inferiority study evaluated the safety of infant formulas enriched with bovine milk fat globule membrane (MFGM) fractions.MethodsHealthy, full-term infants ( n = 119) age ≤14 days were randomized to standard infant formula (control), standard formula enriched with a lipid-rich MFGM fraction (MFGM-L), or standard formula enriched with a protein-rich MFGM fraction (MFGM-P). Primary outcome was mean weight gain per day from enrollment to age 4 months (non-inferiority margin: –3.0 g/day). Secondary (length, head circumference, tolerability, morbidity, adverse events) and exploratory (phospholipids, metabolic markers, immune markers) outcomes were also evaluated.Res…

safetymedicine.medical_specialtyinfant feedingbusiness.industrygrowthGeneral Engineeringlcsh:RJ1-570lcsh:PediatricsGastroenterologyPrimary outcomeTolerabilityStandard infant formulaformula toleranceInternal medicineMedicineNon inferiority trialGlobules of fatmedicine.symptombusinessAdverse effectMilk fat globuleWeight gainBiomedical engineeringOriginal Researchmilk fat globule membraneClinical Medicine Insights: Pediatrics
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368 Growth of Infant Fed Starter Formula Containing Prebiotics or Symbiotic

2010

Objective: To assess growth of infants fed starter formula supplemented with either prebiotics or symbiotic. In addition, gut microbiota was studied. Methods: Healthy, full term newborns (n= 240) were enrolled before the 14th day of their life and randomly assigned between 3 exclusively formula fed groups: starter IF, starter IF + prebiotics (CMOS+GOS), starter IF + prebiotics (CMOS+GOS) and probiotics (BL999 + LPR). Growth was assessed by body weight gain during 4 months. Gut microbiota profile was examined by measuring fecal counts in Bifidobacteria, Lactobacilli, Enterobacteria, Clostridium at 2 months of age. Incidence of morbidity was appraised. Results: Non inferiority in growth was e…

biologyPrebioticmedicine.medical_treatmentIncidence (epidemiology)Gut florabiology.organism_classificationConfidence intervalAnimal scienceClostridiumStarterPediatrics Perinatology and Child HealthmedicineFecesFull TermPediatric Research
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Growth of Infant Fed Starter Formula Containing Milk Fat Globule Membranes

2011

Objective: To assess growth of infants fed starter formula supplemented with milk fat globule membranes (MFGM).

MembraneStarterChemistryPediatric researchPediatrics Perinatology and Child HealthImmunologytechnology industry and agriculturebacteriafood and beveragesFood scienceMilk fat globulePediatric Research
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