0000000000008038

AUTHOR

Alejandro De La Sierra

showing 9 related works from this author

Effectiveness and Tolerability of Fixed-Dose Combination Enalapril plus Nitrendipine in Hypertensive Patients Results of the 3-Month Observational, P…

2009

Background and objective: Monotherapy with any class of antihypertensive drug effectively controls blood pressure (BP) in only about 50% of patients. Consequently, the majority of patients with hypertension require combined therapy with two or more medications. This study aimed to evaluate the effectiveness (systolic BP [SBP]/diastolic BP [DBP] control) and tolerability of the fixed-dose combination enalapril/nitrendipine 10 mg/20 mg administered as a single daily dose in hypertensive patients. Methods: This was a post-authorization, multicentre, prospective, observational study conducted in primary care with a 3-month follow-up. Patients throughout Spain with uncontrolled hypertension (>= …

Malemedicine.medical_specialtymedicine.drug_classSystolic hypertensionFixed-dose combinationPopulationAngiotensin-Converting Enzyme InhibitorsBlood PressureEssential hypertensionEnalaprilInternal medicinemedicineProduct Surveillance PostmarketingHumansPharmacology (medical)EnalaprilProspective StudieseducationAntihypertensive drugAntihypertensive Agentseducation.field_of_studyDose-Response Relationship DrugPrimary Health Carebusiness.industryNitrendipineGeneral MedicineMiddle Agedmedicine.diseaseCalcium Channel BlockersDrug CombinationsBlood pressureTolerabilityAnesthesiaHypertensionFemalebusinessmedicine.drug
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Response to Nondipping in Patients With Hypertension

2009

We thank Ben-Dov and Bursztyn for their interest in our article1 and also for their positive feedback and criticism.2 We would like to try to answer directly to the 3 points raised in their letter. First, is siesta influencing the nocturnal BP dip? In the Spanish ambulatory blood pressure monitoring registry, the daytime period was calculated from the time of wake-up in the morning to the time of going to bed in the evening. However, in our opinion, 2 aspects minimize a possible …

medicine.medical_specialtyAmbulatory blood pressureEveningbusiness.industryNocturnalSiestaEndocrinologyInternal medicineEmergency medicineInternal MedicinemedicineIn patientbusinessMorningHypertension
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European Society of Hypertension practice guidelines for ambulatory blood pressure monitoring

2014

Given the increasing use of ambulatory blood pressure monitoring (ABPM) in both clinical practice and hypertension research, a group of scientists, participating in the European Society of Hypertension Working Group on blood pressure monitoring and cardiovascular variability, in year 2013 published a comprehensive position paper dealing with all aspects of the technique, based on the available scientific evidence for ABPM. The present work represents an updated schematic summary of the most important aspects related to the use of ABPM in daily practice, and is aimed at providing recommendations for proper use of this technique in a clinical setting by both specialists and practicing physici…

AdultMalemedicine.medical_specialtyAmbulatory blood pressureAdolescentPhysiologyMEDLINEPharmacyWhite coat hypertensionPractice PatternsBlood Pressure MonitoringMasked HypertensionAtrial FibrillationAmbulatoryInternal MedicinemedicineHumansambulatory blood pressure monitoring arterial hypertension clinic blood pressure measurement clinical indications guidelines home blood pressure measurement practice recommendationsObesityPractice Patterns Physicians'ChildIntensive care medicineReimbursementPhysicians'business.industryMED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLAREBlood Pressure Monitoring Ambulatorymedicine.disease3. Good healthMasked HypertensionBlood pressureHypertensionPosition paperFemaleCardiology and Cardiovascular MedicinebusinessSoftwareWhite Coat HypertensionJournal of Hypertension
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Response to Timing of Antihypertensive Therapy and Circadian Blood Pressure Pattern

2009

We thank Almirall et al1 for their interest in our article.2 In the present answer to their letter, we provide data from the Spanish Ambulatory Blood Pressure Monitoring Registry regarding clinical differences among patients depending on the time that they received their medication (Table). As shown, several differences were evident among groups, with respect to age, duration of hypertension, prevalence of diabetes mellitus, and history of …

medicine.medical_specialtyAmbulatory blood pressureCircadian blood pressurebusiness.industryDiabetes mellitusEmergency medicineInternal MedicineMedicinebusinessmedicine.diseaseIntensive care medicineHypertension
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COSMIC project : consensus on the objectives of the metabolic syndrome in clinic

2018

Juan Pedro-Botet,1 Juan F Ascaso,2,3 Vivencio Barrios,4,5 Alejandro De la Sierra,6 Javier Escalada,7,8 Jesús Millán,9 Jose M Mostaza,10 Pablo Pérez-Martínez,8,11 Xavier Pintó,8,12 Jordi Salas-Salvadó,8,13 Pedro Valdivielso14 1Lipids and Vascular Risk Unit, Hospital del Mar, Universitat Autònoma de Barcelona, Barcelona, Spain; 2Endocrinology and Nutrition Service, Hospital Clínico, Universitat de Valencia, Valencia, Spain; 3INCLIVA Research Institute, Diabetes and Metabolic Diseases Ciber (Networked Biomedical Research Centres – CIBERDEM), Carlos III, Valencia, Spain; 4Cardiology Service, Hospital Universitario Ramón y Caja…

medicine.medical_specialtydiabetes preventionSpecialties of internal medicineReviewDiseaseType 2 diabetes030204 cardiovascular system & hematologymetabolic syndromeScientific evidence03 medical and health sciences0302 clinical medicineDiabetes mellitusinsulin resistanceInternal MedicinemedicineCor -- Malalties -- Prevenció030212 general & internal medicineObesityRisk factorDiabetes preventionIntensive care medicineAbdominal obesityobesity.Pharmacologybusiness.industrycardiovascular preventionInsulin resistancemedicine.diseaseDiabetis -- PrevencióCardiovascular preventionRC581-951DyslipidemiaHypertensionObesitatHipertensióMetabolic syndromemedicine.symptombusinessDyslipidemia
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Methodology and technology for peripheral and central blood pressure and blood pressure variability measurement: current status and future directions…

2016

Office blood pressure measurement has been the basis for hypertension evaluation for almost a century. However, the evaluation of blood pressure out of the office using ambulatory or self-home monitoring is now strongly recommended for the accurate diagnosis in many, if not all, cases with suspected hypertension. Moreover, there is evidence that the variability of blood pressure might offer prognostic information that is independent of the average blood pressure level. Recently, advancement in technology has provided noninvasive evaluation of central (aortic) blood pressure, which might have attributes that are additive to the conventional brachial blood pressure measurement. This position …

Position statementmedicine.medical_specialtyAmbulatory blood pressurePhysiologycentral blood pressureBlood Pressureclinic blood pressure030204 cardiovascular system & hematologylaw.inventionperipheral blood pressure03 medical and health sciences0302 clinical medicineCentral blood pressurelawaortic blood pressuremedicineInternal MedicineHumansBlood pressure monitoring030212 general & internal medicineIntensive care medicineambulatory blood pressureSocieties Medicalbrachial blood pressurebusiness.industryself-measurementMedicine (all)Blood Pressure DeterminationPeripheralEuropemonitoringPressure measurementBlood pressurePractice Guidelines as TopicAmbulatoryblood pressure variabilitymeasurementbusinessCardiology and Cardiovascular Medicine
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MASked-unconTrolled hypERtension management based on office BP or on ambulatory blood pressure measurement (MASTER) Study: a randomised controlled tr…

2018

Introduction Masked uncontrolled hypertension (MUCH) carries an increased risk of cardiovascular (CV) complications and can be identified through combined use of office (O) and ambulatory (A) blood pressure (BP) monitoring (M) in treated patients. However, it is still debated whether the information carried by ABPM should be considered for MUCH management. Aim of the MASked-unconTrolled hypERtension management based on OBP or on ambulatory blood pressure measurement (MASTER) Study is to assess the impact on outcome of MUCH management based on OBPM or ABPM. Methods and analysis MASTER is a 4-year prospective, randomised, open-label, blinded-endpoint investigation. A total of 1240 treated hyp…

HYPERTENSION MANAGEMENTHipertensión.1302masked uncontrolled hypertensionEnfermedades cardiovasculares - Pacientes - Factores de riesgo.office blood pressureMASKED UNCONTROLLED HYPERTENSIONMedicina ClínicaCardiovascular Medicine030204 cardiovascular system & hematologyAMBULATORY BLOOD PRESSURE MONITORINGlaw.invention0302 clinical medicineClinical trialsRandomized controlled triallawBlood Pressure MonitoringMasked Hypertension//purl.org/becyt/ford/3.2 [https]ProtocolMulticenter Studies as Topic1506030212 general & internal medicineCardiovascular system - Diseases - Patients - Risk factors.Blood pressure.OFFICE BLOOD PRESSURERandomized Controlled Trials as TopicSistemas Cardíaco y CardiovascularGeneral MedicineBlood Pressure Monitoring Ambulatory3. Good healthCor MalaltiesEchocardiographyAmbulatoryHypertensionBlood pressure//purl.org/becyt/ford/3 [https]Hipertensióambulatory blood pressure monitoring; hypertension; hypertension management; masked uncontrolled hypertension; office blood pressure; treated hypertensive patientsTREATED HYPERTENSIVE PATIENTS1683medicine.medical_specialtyAmbulatory blood pressureCIENCIAS MÉDICAS Y DE LA SALUDhypertensionHeart Ventriclestreated hypertensive patientPressió sanguínia03 medical and health sciencesAmbulatoryHypertension.medicineAlbuminuriaHumansAntihypertensive AgentsProtocol (science)business.industryConsolidated Standards of Reporting Trialsambulatory blood pressure monitoring; hypertension; hypertension management; masked uncontrolled hypertension; office blood pressure; treated hypertensive patients; Albuminuria; Antihypertensive Agents; Echocardiography; Heart Ventricles; Humans; Masked Hypertension; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Blood Pressure Monitoring Ambulatorytreated hypertensive patientsambulatory blood pressure monitoringBlood pressurePresión sanguínea.Good clinical practiceEmergency medicinebusinessDeclaration of Helsinkihypertension managementAssaigs clínicsBMJ Open
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COSMIC project: consensus on the objectives of the metabolic syndrome in clinic

2018

Juan Pedro-Botet,1 Juan F Ascaso,2,3 Vivencio Barrios,4,5 Alejandro De la Sierra,6 Javier Escalada,7,8 Jesús Millán,9 Jose M Mostaza,10 Pablo Pérez-Martínez,8,11 Xavier Pintó,8,12 Jordi Salas-Salvadó,8,13 Pedro Valdivielso14 1Lipids and Vascular Risk Unit, Hospital del Mar, Universitat Autònoma de Barcelona, Barcelona, Spain; 2Endocrinology and Nutrition Service, Hospital Clínico, Universitat de Valencia, Valencia, Spain; 3INCLIVA Research Institute, Diabetes and Metabolic Diseases Ciber (Networked Biomedical Research Centres – CIBERDEM), Carlos III, Valencia, Spain; 4Cardiology Service, Hospit…

Targets and Therapy [Diabetes Metabolic Syndrome and Obesity]Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
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European society of hypertension position paper on ambulatory blood pressure monitoring

2013

Ambulatory blood pressure monitoring (ABPM) is being used increasingly in both clinical practice and hypertension research. Although there are many guidelines that emphasize the indications for ABPM, there is no comprehensive guideline dealing with all aspects of the technique. It was agreed at a consensus meeting on ABPM in Milan in 2011 that the 34 attendees should prepare a comprehensive position paper on the scientific evidence for ABPM.This position paper considers the historical background, the advantages and limitations of ABPM, the threshold levels for practice, and the cost-effectiveness of the technique. It examines the need for selecting an appropriate device, the accuracy of dev…

Arterial hypertensionmedicine.medical_specialtyAmbulatory blood pressurePhysiologyMEDLINEWhite coat hypertension030204 cardiovascular system & hematologylaw.invention03 medical and health sciencesresearch application0302 clinical medicineRandomized controlled triallawInternal Medicinemedicine030212 general & internal medicineguidelinesIntensive care medicineambulatory blood pressure monitoring clinic blood pressure measurement clinical indications guidelines home blood pressure measurement recommendations research applicationReimbursementbusiness.industryGuidelinemedicine.diseasehome blood pressure measurement3. Good healthMasked Hypertensionambulatory blood pressure monitoringrecommendationsPosition paperclinic blood pressure measurementCardiology and Cardiovascular Medicinebusinessclinical indications
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