0000000000009530

AUTHOR

Florence Molinie

0000-0002-0645-4017

showing 5 related works from this author

Unbiased estimates of long-term net survival of solid cancers in France

2013

In cancer studies, net survival (observed if cancer was the only cause of death) is a useful indicator but survival estimation at 5 years is insufficient for planning healthcare needs. We estimated the net survivals at 5 and 10 years in a cohort of 387,961 patients who had solid tumors between 1989 and 2004 and were followed-up until January 1, 2008. The cases were actively followed-up. Net survival was estimated with the unbiased Pohar-Perme method. The standardized net survival used the international cancer survival standard weights. In men, the standardized net survivals ranged from 92% at 5 years and 89% at 10 years (testis) to 6% at 5 years and 5% at 10 years (pancreas). In women, it r…

AdultMaleCancer Researchmedicine.medical_specialty[SDV]Life Sciences [q-bio]03 medical and health sciences0302 clinical medicineBreast cancerAge DistributionBiasRisk FactorsNeoplasmsmedicineHumans030212 general & internal medicineRegistriesSex DistributionNet SurvivalSurvival analysisCause of deathAgedModels Statisticalbusiness.industrySurvival estimationAge FactorsCancerMiddle Agedmedicine.diseasePrognosisSurvival Analysis3. Good healthSurgeryOncology030220 oncology & carcinogenesisCancer managementCohortFemaleFrancebusinessDemography
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How do age and social environment affect the dynamics of death hazard and survival in patients with breast or gynecological cancer in France?

2021

Several studies have investigated the association between net survival and social inequalities in people with cancer, highlighting a varying influence of deprivation depending on the type of cancer studied. However, few of these studies have accounted for the effect of social inequalities over the follow-up period, and/or according to the age of the patients. Thus, using recent and more relevant statistical models, we investigated the effect of social environment on net survival in women with breast or gynecological cancer in France. The data were derived from population-based cancer registries, and women diagnosed with breast or gynecological cancer between 2006 and 2009 were included. We …

AdultCancer ResearchDeprivationGenital Neoplasms FemalePopulationBreast NeoplasmsAffect (psychology)03 medical and health sciencesNet survival0302 clinical medicineBreast cancerBreast cancerMedicineHumansSocial inequality030212 general & internal medicineRegistrieseducationAgedCervical cancerAged 80 and overeducation.field_of_studybusiness.industryAge FactorsSocial environmentCancerMiddle Agedmedicine.diseasePrognosis3. Good healthSurvival RateSocial environmentOncologySocioeconomic Factors030220 oncology & carcinogenesisGynecological cancerFemale[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologieFrancebusinessOvarian cancerDemographyFollow-Up Studies
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Socioeconomic Environment and Survival in Patients with Digestive Cancers: A French Population-Based Study

2021

Simple Summary Studies investigating the social gradient in digestive cancer survival are scarce, and the statistical methods used do not always consider important assumptions in survival analysis for adequate assessment. Using an ecological index (European Deprivation Index), we found a negative impact of social environment in digestive cancers net survival (especially for esophagus, stomach, bile ducts among females; colon and rectum for both sexes) and provided insight into how this social gradient in cancer survival builds up, and at what time of follow-up it appears. These results can guide clinical practice/public health actions to address social inequalities in survival by targeting …

Cancer ResearchColorectal cancerPopulationArticleBile duct cancerdeprivationmedicineFrench cancer registrieseducationSocioeconomic statusRC254-282education.field_of_studybusiness.industryBile ductStomachsocial gradientdigestive cancersNeoplasms. Tumors. Oncology. Including cancer and carcinogensSocial environmentCancermedicine.diseasemedicine.anatomical_structureOncologycancer net survivalbusinessdigestive cancers; cancer net survival; deprivation; social gradient; French cancer registriesDemographyCancers
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Management of rectal cancer in France in a well-defined population.

2014

Objective The aim of this study was to draw a picture of diagnostic assessment and patterns of care for rectal cancer in France using population-based registries data. Methods The study included a random sample of 669 cases of rectal cancers diagnosed in 2005. Results Diagnostic assessment was performed by colonoscopy in 91.4% of the cases. An abdominal computed tomography was performed in 59.4% of the cases and chest computed tomography in 47.8%. An R0 resection was performed in 65.8% of cases and an R1/R2 resection in 16.1%. A rectal endosocography was performed in 40.4% and MRI in 10.4%. The sphincter was preserved in 73.6% of patients aged younger than 75 years of age and in 62.5% of th…

medicine.medical_specialtyColorectal cancermedicine.medical_treatmentPopulationColonoscopyAnal CanalPreoperative carePreoperative CaremedicineHumansRegistriesStage (cooking)educationAgedNeoplasm Stagingeducation.field_of_studyHepatologymedicine.diagnostic_testbusiness.industryRectal NeoplasmsPalliative CareGastroenterologyAge FactorsChemoradiotherapy AdjuvantColonoscopymedicine.diseaseRadiation therapymedicine.anatomical_structureSphincterRadiologyFrancebusinessTomography X-Ray ComputedChemoradiotherapyEuropean journal of gastroenterologyhepatology
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Burden and centralised treatment in Europe of rare tumours: results of RARECAREnet—a population-based study

2017

Background: Rare cancers pose challenges for diagnosis, treatments, and clinical decision making. Information about rare cancers is scant. The RARECARE project defined rare cancers as those with an annual incidence of less than six per 100 000 people in European Union (EU). We updated the estimates of the burden of rare cancers in Europe, their time trends in incidence and survival, and provide information about centralisation of treatments in seven European countries. Methods: We analysed data from 94 cancer registries for more than 2 million rare cancer diagnoses, to estimate European incidence and survival in 2000–07 and the corresponding time trends during 1995–2007. Incidence was calcu…

Male0301 basic medicinePathologypopulation-based registriesCancer Care Facilities; Delivery of Health Care; Europe; Female; Hospitalization; Humans; Incidence; Male; Neoplasms; Rare Diseases; Registries; Survival Rate; Oncology0302 clinical medicineNeoplasmsMedicineRegistriesmedia_commonTumors -- Treatment -- Europeeducation.field_of_studyRelative survivalIncidenceIncidence (epidemiology)RARECARE projectEuropeHospitalizationSurvival RateOncology030220 oncology & carcinogenesis/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingFemalemedicine.medical_specialtyHealth surveysPopulationSocio-culturaleCancer Care Facilities03 medical and health sciencesRare DiseasesSDG 3 - Good Health and Well-beingHumansmedia_common.cataloged_instanceCancer -- MortalityRisk factorEuropean unioneducationSurvival rateOncology cancer burden incidence rare cancerpopulation-based registriesrare cancers cancer registry RARECAREbusiness.industryRare cancerCancer -- Patients -- Long-term careCancer registry030104 developmental biologycancer burdenbusinessDelivery of Health CareDemographyRare disease
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