New Ruthenium complexes with antitumoral activity

How organotin(IV)(sulfonatophenyl) porphynate may activate the apoptotic pathways in melanoma cells?

Organotin(IV)(sulfonatophenyl)porphynate effects on survival and apoptotic signalling pathways in melanoma cells

TPPS derivatives induce apoptosis on A375 human melanoma cells

Synthesis, structural investigation and biological activity of metal ions complexes of N-acetylcysteine and carbocysteine

Complessi di nuova sintesi di derivati della cisteina con ioni metallici

Studi strutturali e indagini biologiche di nuovi complessi di rutenio(III) con 1- tioglucosio e 1-metiluracile

Synthesis, structural investigation and biological activity of new diorganotin(IV) N-acetylcysteine Complexes.

(Bu3Sn)4TPPS and (Bu2Sn)2TPPS significantly inhibit the growth, migrationand tumorigenicity of human malignant melanoma cells

Melanoma is one of the most aggressive and treatment-resistant human cancers, it is responsible worldwide for the 80% of skin cancer related deaths which is largely due to its propensity to metastasize to other organs. The growing understanding of the pathways involved in melanoma progression and development has led to the identification of some interesting new molecules, however, the treatment options for metastatic melanoma remain limited. Indeed, the key step in metastasis development is the tumour cell invasion of the nearby host tissue and the journey powerfully depends on the detachment of single tumour cells from the primary tumour. Therefore, the ability to block the migratory and i…