0000000000012634
AUTHOR
Giulia Cancellieri
METHADONE VERSUS BUPRENORPHINE: DATA DETECTED FROM CALTANISSETTA SER.T
In last years, heroin-addicted have exponentially increased: this has made it necessary to identify a pharmacological strategy as effective as possible. With this purpose, a statistical investigation was conducted in a sample of individuals, aged between 18 and 50. They were diagnosed and subjected to different treatments at Ser.T of Caltanissetta (Sicily-Italy) during the period 2013-2017. The analyzed patients were treated with three different pharmacological therapy: methadone 0.1%, methadone 0.5%, buprenorphine and suboxone. We obtained percentages of RESPONDERS, LOW RESPONDERS and NON RESPONDERS patients from data processing, based on used therapy. Considering pharmacological responses…
STATISTICAL ANALYSIS ABOUT DIFFUSION OF EXERCISE ADDICTION IN SICILY
Exercise Addiction (EA) is a behavioral dysfunction marked by uncontrolled compulsion towards all kinds of physical activity. With the purpose of understanding the epidemiology of this steadily increasing phenomenon, we have done a statistical analysis about some data obtained through the administration of an online-questionnaire (Google forms): the same one was also converted into paper-questionnaire and then it has been administered in many gyms in Palermo and Trapani (Sicily-Italy). The sample examined consists of 976 people aged between 14 and 65 (47.3% of them are women and 52.7% are men). For 53.8% of analyzed people, physical activity is one of the most important things of their life…
Immuno-oncological treatment of Non-Small-Cell Lung Cancer (NSCLC) in advanced stage with Nivolumab
Immuno-oncology marked a therapeutic revolution in the treatment of cancer. Thanks to the new strategy that aims to awaken the immune system to fight cancer cells, there has been a change in the clinical course in the treatment of advanced Non-Small Cell Lung Cancer (NSCLC). Our study aimed to evaluate the therapeutic efficacy of nivolumab monotherapy in the treatment of patients with advanced stage IIIB/IV non-small cell lung cancer beyond the second line. The results showed a progression-free survival of 7.35 months and an improvement in the quality of life of patients compared to other treatments. In addition, no type 3 and type 4 adverse reactions were detected in patients treated with …
AMATEUR DOPING: A SURVEY AMONG SICILIAN PEOPLE
In last years, Amateur Doping has caused many victims. In order to know the diffusion of this phenomenon, we have conducted an online-survey through Google forms. We also transformed the same questionnaire on paper and it was administered in many gyms in Palermo and Trapani (Sicily-Italy). The sample examined consists of 976 people aged between 14 and 65 (47.3% of them are women and 52.7% are men). We asked them if they ever took on substances to improve their athletic performances: 25.8% of them answered affirmatively and they declared to take on protein, amino acids but also Eca Stacks, which are hired on regular basis (34.6%). They bought this substances in sporting stores (32.2%), in ph…
Gambling: spreading among students in Palermo
Adolescents represent a particularly high-risk group and they are also vulnerable to the development of gambling related problems. Thanks to technological advances in gaming industry (slot machines, video lottery terminals, casino-types games) new form of gambling are continuously appearing. With the purpose of having an idea about the spreading of gambling among the students of Palermo, a survey has been conducted through administration of questionnaires during the period from January to May 2017: this study involved 1622 students (686 boys and 936 girls) between the age of 14 and 19. In this survey it has been demonstrated that only 15% of students have never played; 36% declare they have…
DETECTION, ANALYSIS AND PROCESSING OF ACUTE ALCOHOL INTOXICATIONS COLLECTED AT EMERGENCY DEPARTMENT OF THE “GARIBALDI CENTRO” HOSPITAL IN CATANIA
The study we conducted was highlighted the main clinical aspects of voluntary or accidental acute alcohol intoxication. These intoxication were identified over the five-year period between 2015 and 2019, and we evaluated its pharmacological management by statistical analysis of clinical cases detected at the Emergency Department of “Garibaldi Centro” Hospital in Catania. The extrapolated data showed that acute alcohol intoxications are the main reason of access to the Emergency Department (65%) to which drugs (17%), addicted substances (8%), and other substances (caustics, food, gases and vapours, detergents and soaps, benzene and pesticides, 10%). It has been shown that the most commonly u…
IMMUNO-ONCOLOGICAL TREATMENT OF NON-SMALL-CELL LUNG CANCER IN ADVANCED STAGE WITH NIVOLUMAB
In recent years, significant scientific progress has been made in the therapy of non-small cell lung cancer (NSCLC),which has made possible a better knowledge of this pathology and above all the realization of new personalized therapies. The main therapeutic revolution in advanced NSCLC is immunooncology, a new therapeutic strategy that aims to awaken the immune system to fight cancer cells. Our work helped us evaluate the therapeutic efficacy of monotherapy with Nivolumab in the treatment of patients with advanced stage IIIB/IV non-smallcell lung cancer beyond the second line. We can conclude that in the treatment of non-small-cell lung cancer, the use of Nivolumab improves the prognosis a…
Rilevazione statistica della diffusione dei fenomeni di binge drinking, drunkoressia e gambling tra gli adolescenti palermitani
L’obiettivo dello studio è l’analisi della diffusione dei comportamenti riconducibili ai fenomeni di Binge Drinking, Drunkoressia e Gambling in individui che possiedono un’età compresa tra i 13 e 20 anni: si è deciso di analizzare nello specifico tale fascia d’età poiché la propensione di alcuni soggetti ad assumere condotte pericolose per la propria salute risulta essere particolarmente alta proprio durante la fase adolescenziale. Quest’ultimo è infatti un periodo di intenso sviluppo neuro- cognitivo che conduce a cambiamenti importanti ai fini del comportamento, dell’affettività, della ricerca e della selezione di stimoli più gratificanti: il risultato è un aumento della predisposizione a…
Statistical survey focused on diffusion and knowledge of energy drinks, conducted in Palermo
In recent years energy drinks consumption has increased, due to their ability to improve physical and cognitive performance. Unfortunately, because of poor or incorrect information, people are not always aware of the harmful consequences of these drinks such as obesity, diabetes, hypertension, tachycardia until death. Therefore, we conducted a statistical survey in the Palermo area, submitting a paper questionnaire to 1003 people. Data analysis shows that only 29% of the audience never consumed energy drinks, while 71% tried them at least once in their life, especially in adolescence; 81% never or rarely drink them, 14% drink them a few times a month, while 5% drink them several times a wee…
Methadone versus buprenorphine: data detected from Caltanissetta SER.T
In last years, heroin-addicted have exponentially increased: this has made it necessary to identify a pharmacological strategy as effective as possible. With this purpose, a statistical investigation was conducted in a sample of individuals, aged between 18 and 50. They were diagnosed and subjected to different treatments at Ser.T of Caltanissetta (Sicily-Italy) during the period 2013-2017. The analyzed patients were treated with three different pharmacological therapy: methadone 0.1%, methadone 0.5%, buprenorphine and suboxone. We obtained percentages of responders, low responders and non-responders patients from data processing, based on used therapy. Considering pharmacological responses…
Bempedoic acid as adjunct for traditional lipid-lowering therapy in patients with hyperlipidaemia
Statin therapy has been the cornerstone for the reduction of cholesterol and circulating low-density lipoprotein (LDL) in patients with cardiovascular diseases. However, statin monotherapy has disadvantages attributable to myopathies and to the insufficient cholesterol reduction observed in some patients. There is a need for new well-tolerated therapies for lowering LDL. This review will focus on bempedoic acid in combination with traditional statin therapy or other lipid-lowering agents and its emerging role in LDL-C lowering. Bempedoic acid is also a viable alternative for reducing LDL cholesterol in the treatment of some patients suffering from heterozygous familial hypercholesterolemia.
Statistical analysis of a survey about diffusion of binge drinking and drunkorexia among students in Palermo
Youth alcohol consumption is a major global public health concern. Previous reviews have concluded that exposure to alcohol marketing was associated with drinking initiation and higher alcohol consumption among youth. From January to May 2017, a survey has been conducted through administration of questionnaires about the diffusion of Binge Drinking and Drunkorexia among the students of Palermo. Test was administered, during school time, to 2331 students between the ages of 13 and 20. Regarding the analysis of the questionnaires, 97,8% of student declares to have drunk at least once: their first taste of alcoholic drink happens at the age of thirteen/fourteen. They prefer to drink at the dis…
DETECTION OF THE DIFFUSION AND KNOWLEDGE OF ENERGY DRINKS, CONDUCTED THROUGH A STATISTICAL SURVEY ON PALERMO AREA
In recent years energy drinks consumption has increased, due to their ability to improve physical and cognitive performance. Unfortunately, because of poor or incorrect information, people are not always aware of the harmful consequences of these drinks such as obesity, diabetes, hypertension, tachycardia until death. Therefore, we conducted a statistical survey in Palermo area, submitting a paper questionnaire to 1003 people. Data analysis shows that: only 29% of the audience never consumed energy drinks, while 71% tried them at least once in their life, especially in adolescence; 81% never or rarely drink them, 14% drink them a few times a month, while 5% drink them several times a week; …
Amateur doping: a survey on Sicilian population
In the last years, amateur doping phenomenon has caused many victims. In order to know the diffusion of this phenomenon, we conducted an online survey thanks to Google forms. We also converted on paper the same questionnaire and we administered it in many gyms in Palermo and Trapani (Sicily, Italy). The examined sample consists of 976 people aged between 14 and 65 (47.3% of them are women and 52.7% are men). We asked them if they had ever taken substances to improve their athletic performances: 25.8% of them answered affirmatively and declared to take protein, amino acids, but also Ephedrine, Caffeine, Aspirin on a regular basis (34.6%). They bought these substances in sporting stores (32.2…