0000000000012690

AUTHOR

Ulf Gieseler

showing 3 related works from this author

Impact of prehospital delay on mortality in patients with acute myocardial infarction treated with primary angioplasty and intravenous thrombolysis.

2001

Abstract Background In patients with acute myocardial infarction treated with thrombolysis, longer times to treatment are associated with increasingly worse clinical outcome. This relation may be different for treatment with primary angioplasty. Methods We analyzed the pooled data of the German acute myocardial infarction registries Maximal Individual Therapy in Acute Myocardial Infarction (MITRA) and Myocardial Infarction Registry (MIR) to determine the influence of prehospital delays on hospital mortality rates. Primary angioplasty was performed in 1063 patients and thrombolysis in 7552 patients. Results In patients treated with thrombolysis, in-hospital time to treatment was constantly 3…

Malemedicine.medical_specialtyTime Factorsmedicine.medical_treatmentTime to treatmentPrimary angioplastyMyocardial InfarctionStatistics NonparametricInternal medicineFibrinolysismedicineHumansIn patientThrombolytic TherapyMyocardial infarctionHospital MortalityProspective StudiesRegistriesChemotherapyChi-Square Distributionbusiness.industryMortality rateThrombolysisMiddle Agedmedicine.diseaseSurgeryTreatment OutcomeCardiologyFemaleCardiology and Cardiovascular MedicinebusinessAngioplasty BalloonAmerican heart journal
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Gender differences in acute myocardial infarction in the era of reperfusion (the MITRA registry).

2002

There is conflicting information about gender differences in presentation, treatment, and outcome after acute ST elevation myocardial infarction (STEMI) in the era of thrombolytic therapy and primary percutaneous coronary intervention. From June 1994 to January 1997, we enrolled 6,067 consecutive patients with STEMI admitted to 54 hospitals in southwest Germany in the Maximal Individual TheRapy of Acute myocardial infarction (MITRA), a community-based registry. Women were 9 years older than men, more often had hypertension, diabetes mellitus, and congestive heart failure, and had a history of previous myocardial infarction less often. Women had a longer prehospital delay (45 minutes), had a…

Malemedicine.medical_specialtyEmergency Medical Servicesmedicine.medical_treatmentMyocardial InfarctionInfarctionAngina PectorisAnginaReperfusion therapySex FactorsInternal medicineGermanymedicineHumansThrombolytic TherapyMyocardial infarctionHospital MortalityProspective StudiesRegistriesAgedHeart Failurebusiness.industryPercutaneous coronary interventionThrombolysisOdds ratioMiddle Agedmedicine.diseaseSurvival AnalysisHeart failureCardiologyFemaleCardiology and Cardiovascular MedicinebusinessThe American journal of cardiology
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Comparison of primary angioplasty with conservative therapy in patients with acute myocardial infarction and contraindications for thrombolytic thera…

1999

The benefit of primary angioplasty in patients with acute myocardial infarction (AMI) and contraindications for thrombolysis compared to a conservative regimen is still unclear. Out of 5,869 patients with AMI registered by the MITRA trial, 337 (5.7%) patients had at least one strong contraindication for thrombolytic therapy. Out of these 337 patients 46 (13.6%) were treated with primary angioplasty and 276 (86.4%) were treated conservatively. Patients treated conservatively were older (70 years vs. 60 years; P = 0.001), had a higher rate of a history with chronic heart failure (14.8% vs. 4.4%; P = 0.053), a higher heart rate at admission (86 beats/min vs. 74 beats/min; P = 0.001), and a hig…

Aspirinmedicine.medical_specialtybusiness.industrymedicine.medical_treatmentGeneral MedicineThrombolysismedicine.diseaseRegimenInternal medicineDiabetes mellitusHeart failureHeart ratemedicineCardiologyRadiology Nuclear Medicine and imagingMyocardial infarctionCardiology and Cardiovascular MedicinebusinessContraindicationmedicine.drugCatheterization and Cardiovascular Interventions
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