0000000000014146

AUTHOR

Laura Marelli

showing 3 related works from this author

Comparison of cystatin C and creatinine-based glomerular filtration rate formulas with 51Cr-EDTA clearance in patients with cirrhosis

2011

Renal function is an important predictor of survival in cirrhosis and liver transplantation. GFR estimates using serum cystatin C (CysC) are proposed as better predictors of renal function than ones on the basis of serum creatinine (Cr). Our aims were: (1) evaluate correlations between serum CysC and different methods of creatinine measurements; (2) compare CysC and Cr GFR formulas with (51)Cr-EDTA; and (3) evaluate liver-related parameters potentially influencing GFR.254 blood samples in 65 patients with cirrhosis correlating CysC with four Cr methods were used; another 74 patients comparing (51)Cr-EDTA GFR to Modification of Diet in Renal Disease and Larsson and Hoek formulas for CysC wer…

AdultLiver CirrhosisMalemedicine.medical_specialtyCirrhosisBilirubinEpidemiologymedicine.medical_treatmentUrologyRenal functionLiver transplantationurologic and male genital diseasesCritical Care and Intensive Care MedicineAdult; Aged; Aged 80 and over; Bilirubin; Creatinine; Cystatin C; Female; Humans; Liver Cirrhosis; Male; Middle Aged; Multivariate Analysis; Chromium Radioisotopes; Edetic Acid; Glomerular Filtration Rate; Nephrology; Transplantation; Epidemiology; Critical Care and Intensive Care Medicinechemistry.chemical_compoundBayesian multivariate linear regressionInternal medicine80 and overMedicineHumansCystatin CEdetic AcidAgedAged 80 and overCreatinineTransplantationbiologybusiness.industrycirrhosisBilirubinOriginal Articles51cr edta clearanceMiddle Agedmedicine.diseaseChromium RadioisotopesEndocrinologyCystatin CchemistryNephrologyCreatinineMultivariate Analysisbiology.proteinFemalebusinessGlomerular Filtration Rate
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TACE versus TAE as therapy for hepatocellular carcinoma

2008

Transarterial chemoembolization (TACE) improves survival in cirrhotic patients with hepatocellular carcinoma (HCC). The optimal schedule, best anticancer agent and best technique are still unclear. TACE may not be better than transarterial embolization (TAE). HCC is very chemoresistant, thus embolization may be more important than chemotherapy. Lipiodol cannot be considered as an embolic agent and there are no data to show that it can release chemotherapeutic agents slowly. It can mask residual vascularity on CT imaging and its use is not recommended. Both TACE and TAE result in hypoxia, which stimulates angiogenesis, promoting tumor growth; thus combination of TACE with antiangiogenic agen…

Oncologymedicine.medical_specialtyCarcinoma HepatocellularHepatocellular carcinomaRadiofrequency ablationmedicine.medical_treatmentAntineoplastic Agentslaw.inventionRecurrencelawInternal medicineCarcinomamedicineHumansPharmacology (medical)EmbolizationChemoembolization TherapeuticSurvival rateChemotherapybusiness.industryLiver Neoplasmsmedicine.diseaseSurvival RateTransplantationOncologyHepatocellular carcinomaLipiodolRadiologybusinessmedicine.drugExpert Review of Anticancer Therapy
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The relationship between transient elastography and histological collagen proportionate area for assessing fibrosis in chronic viral hepatitis

2012

Collagen proportionate area (CPA) has a better correlation with hepatic venous pressure gradient (HVPG) than with Ishak stage. Liver stiffness measurement (LSM) is proposed as non invasive marker of portal hypertension/disease progression. Our aim was to compare LSM and CPA with Ishak staging in chronic viral hepatitis, and HVPG in HCV hepatitis after transplantation. One hundred and sixty-nine consecutive patients with chronic hepatitis B virus (HBV) or hepatitis C virus (HCV) infections pre/post liver transplantation (LT), had a liver biopsy combined with LSM (transient elastography), CPA (biopsies stained with Sirius Red and evaluated by digital image analysis and expressed as CPA) and H…

AdultLiver CirrhosisMalemedicine.medical_specialtyCirrhosisHepatitis C virusmedicine.medical_treatmentBiopsyLiver transplantationmedicine.disease_causeGastroenterologyYoung AdultHepatitis B ChronicInternal medicinemedicineImage Processing Computer-AssistedHumansheterocyclic compoundsAgedtransient elastography histological collagen proportionate area fibrosis chronic viral hepatitis.medicine.diagnostic_testbusiness.industryfibrosisGastroenterologyHepatologyHepatitis C ChronicMiddle Agedmedicine.diseasetransient elastographychronic viral hepatitisLiver TransplantationTransplantationhistological collagen proportionate areaLiver biopsyMultivariate Analysiscardiovascular systemDisease ProgressionElasticity Imaging TechniquesRegression AnalysisFemaleCollagenTransient elastographyViral hepatitisbusiness
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