0000000000014514
AUTHOR
Susan D. Horn
Magnetic phase diagrams in heavy-fermion compounds
Magnetic phase diagrams have been explored in heavy-fermion (HF) compounds by controlled changes of the stoichiometry (UCu4+xAl8−x), dopant concentration (Ce(Cu1−xNix)2Ge2) and magnetic field (CeCu2Si2). The results demonstr competition (i) between Kondo and RKKY interactions in the former two compounds and (ii) between HF superconductivity and some cooperative state, presumably HF band magnetism, in the latter.
In vitro expansion and analysis of T lymphocyte microcultures obtained from the vaccination sites of cancer patients undergoing active specific immunization with autologous Newcastle-disease-virus-modified tumour cells
In order to understand further the effects of Newcastle-disease-virus(NDV)-modified tumour vaccines we investigated the feasibility of isolating lymphocytes from the site of injection of patients undergoing postoperative active specific immunization (ASI) with autologous NDV-modified tumour cells. Delayed-type-hypersensitivity(DTH)-like reactions from five cancer patients were surgically removed, minced and the tissue particles were digested with collagenase and DNase. Lymphoid cells recovered were expanded in a highly efficient limiting-dilution analysis system optimized for T cell growth [Moretta et al. (1983) J Exp Med 157: 743] and lymphocyte microcultures (clonal probability > 0.8) cou…
Magnetic order in the heavy fermion system Ce(Cu1−xNix)2Ge2
Abstract The magnetic phase diagram of the heavy fermion (HF) systems Ce(Cu 1−x Ni x ) 2 Ge 2 is discussed utilizing results of transport, thermodynamic and neutron-scattering measurements. While the Kondo temperature increases monotonically with x, a complex x-dependence is found for the Neel temperature, associated with a transition from local-moment to itinerant HF magnetism.
Tumor necrosis factor (TNF)-alpha but not TNF-beta induces secretion of colony stimulating factor for macrophages (CSF-1) by human monocytes
Abstract Tumor necrosis factor (TNF)-alpha has been identified as a major inducer of colony stimulating factor (CSF)-secretion by human vascular endothelial cells and fibroblasts. In the present study we assessed the capacity of TNFs to induce release of CSF-1 from highly purified peripheral blood monocyte preparations. Whereas monocytes do not accumulate CSF-1 messenger (m)RNA constitutively and consequently do not produce CSF-1 protein, CSF-1 mRNA and protein secretion became detectable, when monocytes were cultured in the presence of TNF-alpha, that was synergistically enhanced by interferon-gamma (IFN-gamma). However, under identical experimental conditions TNF-beta failed to induce mon…