0000000000016537

AUTHOR

Sharon E. Oberfield

showing 2 related works from this author

The diagnosis of polycystic ovary syndrome in adolescents

2010

In women, the definition of polycystic ovary syndrome (PCOS) has become broad and includes several possible phenotypes. Because several features of PCOS may be in evolution in adolescents, we suggest that only firm criteria should be used to make a diagnosis of PCOS during adolescence. Hyperandrogenism, oligomenorrhea, and ovarian morphology change during adolescence and are discussed individually. Adolescents with incomplete criteria for a firm diagnosis of PCOS should be followed up carefully and may be diagnosed at a later time.

Hirsutismmedicine.medical_specialtyAdolescentendocrine system diseasesMEDLINESettore MED/13 - EndocrinologiamedicineHumansCystAmenorrheaUltrasonographyMenarcheGynecologybusiness.industryOvaryPubertyHyperandrogenismnutritional and metabolic diseasesObstetrics and Gynecologymedicine.diseasePolycystic ovaryfemale genital diseases and pregnancy complicationsOligomenorrheaOvarian morphologyMenarcheFemaleUltrasonographyHyperandrogenismbusinessPOLYCYSTIC OVARY SYNDROME ADOLESCENCE MENSTRUAL IRREGULARITIES HIRSUTISMAnovulationPolycystic Ovary Syndrome
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Non-classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency revisited: an update with a special focus on adolescent and adult women.

2016

Background Non-classic congenital hyperplasia (NCAH) due to 21-hydroxylase deficiency is a common autosomal recessive disorder characterized by androgen excess. Objective and rationale We conducted a systematic review and critical assessment of the available evidence pertaining to the epidemiology, pathophysiology, diagnosis and management of NCAH. A meta-analysis of epidemiological data was also performed. Search methods Peer-reviewed studies evaluating NCAH published up to October 2016 were reviewed. Multiple databases were searched including MEDLINE, EMBASE, Cochrane, ERIC, EBSCO, dissertation abstracts, and current contents. Outcomes The worldwide prevalence of NCAH amongst women presen…

0301 basic medicineAdultmedicine.medical_specialtyPediatricsHirsutismAdolescentGenetic counseling030209 endocrinology & metabolismDiseaseMiscarriage03 medical and health sciences0302 clinical medicinemedicineHumansCongenital adrenal hyperplasiahirsutismMenstruation DisturbancesGynecologyPregnancyAdrenal Hyperplasia Congenitalbusiness.industry17-alpha-HydroxyprogesteroneHyperandrogenismObstetrics and GynecologyAndrogen Antagonistsmedicine.diseasePolycystic ovary030104 developmental biologyReproductive MedicineFemalebusinessInfertility FemaleHuman reproduction update
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