0000000000017868

AUTHOR

Gabriela García

showing 2 related works from this author

Endometrial receptivity and implantation are not affected by the presence of uterine intramural leiomyomas: a clinical and functional genomics analys…

2008

Uterine leiomyomas are the most frequent benign tumors during reproductive age. Whether intramural leiomyomas cause infertility and should be removed is controversial because no study has addressed the underlying mechanism of infertility.The objective of the study was to test the effect of intramural leiomyomas on endometrial function by comparing gene during the window of implantation and implantation in an oocyte donation program, in which the quality of the embryos replaced is similar and the endocrine environment of the endometrium is standardized by exogenous steroids.Human endometria of women with single intramural leiomyomas (group A,5 cm and group B,or =5 cm) and controls (group C) …

InfertilityAdultmedicine.medical_specialtyPregnancy RateEndocrinology Diabetes and Metabolismmedicine.medical_treatmentClinical BiochemistryUterusContext (language use)BiologyEndometriumBiochemistryModels BiologicalEndometriumEndocrinologyPregnancyInternal medicinemedicineCluster AnalysisHumansEmbryo ImplantationOligonucleotide Array Sequence AnalysisRetrospective StudiesGynecologyIn vitro fertilisationUterine leiomyomaLeiomyomaGene Expression ProfilingBiochemistry (medical)GenomicsMiddle Agedmedicine.diseaseGene Expression Regulation NeoplasticPregnancy ratemedicine.anatomical_structureEndocrinologyIn uteroUterine NeoplasmsFemalePregnancy Complications NeoplasticThe Journal of clinical endocrinology and metabolism
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Implantation is apparently unaffected by the dopamine agonist Cabergoline when administered to prevent ovarian hyperstimulation syndrome in women und…

2007

Background Ovarian hyperstimulation syndrome (OHSS) is a result of ovarian overexpression of vascular endothelial growth factor (VEGF) and its receptor 2 (VEGFR2). VEGF/VEGFR2 binding disrupts cellular junctions and increases vascular permeability (VP), a characteristic of OHSS, but enhances angiogenesis, which is a fundamental step in implantation. In animals, the dopamine agonist Cabergoline (Cb2) prevents VP without affecting angiogenesis. In humans, Cb2 averts OHSS, but a possible detrimental effect on angiogenesis and implantation has not been explored. A pilot study was designed to analyze whether or not Cb2 administration, as a procedure for preventing OHSS, affects the outcome of as…

Adultmedicine.medical_specialtyCabergolinePregnancy RateReproductive Techniques AssistedOvarian hyperstimulation syndromePilot ProjectsBiologyDopamine agonistAndrologyOvarian Hyperstimulation Syndromechemistry.chemical_compoundPregnancyCabergolineInternal medicinemedicineHumansEmbryo ImplantationErgolinesOvarian follicleRetrospective StudiesPregnancyRehabilitationObstetrics and Gynecologymedicine.diseaseVascular endothelial growth factorPregnancy ratemedicine.anatomical_structureEndocrinologyReproductive MedicinechemistryDopamine AgonistsGestationFemalemedicine.drugHuman Reproduction
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