0000000000019671

AUTHOR

Y. Motato

showing 3 related works from this author

Removal of annexin V–positive sperm cells for intracytoplasmic sperm injection in ovum donation cycles does not improve reproductive outcome: a contr…

2014

Objective To determine the effect of removing presumptive apoptotic sperm cells from samples from unselected males by means of magnetic activated cell sorting (MACS) on live-birth delivery rates after intracytoplasmic sperm injection (ICSI) in couples undergoing ovum donation (OD). Design Prospective, randomized, triple-blinded, and controlled study. Setting Private university-affiliated IVF center. Patient(s) A total of 237 infertile couples undergoing ICSI as part of an OD program. Intervention(s) Semen specimens from the control group were prepared by swim-up. Samples from the study group were prepared by swim-up followed by MACS and incubation with annexin V–conjugated microbeads to rem…

AdultMalemedicine.medical_specialtymedicine.medical_treatmentApoptosisSemenCell SeparationFertilization in VitroPhosphatidylserinesBiologyIntracytoplasmic sperm injectionlaw.inventionAndrologyMagneticsHuman fertilizationRandomized controlled trialPregnancylawStatistical significancemedicineHumansSperm Injections IntracytoplasmicAnnexin A5Birth RateGynecologyPregnancyOocyte DonationObstetrics and Gynecologymedicine.diseaseSpermatozoaSpermConfidence intervalSperm MaturationReproductive MedicineFemaleFertility and Sterility
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Morphokinetic analysis and embryonic prediction for blastocyst formation through an integrated time-lapse system.

2015

Objective To describe the events associated with the blastocyst formation and implantation that occur in embryos during preimplantation development based on the largest sample size ever described with time-lapse monitoring. Design Observational, retrospective, single-center clinical study. Setting University-affiliated private IVF center. Patient(s) A total of 7,483 zygotes from 990 first treatments of intracytoplasmic sperm injection (ICSI; 627 of oocyte donor vs. 363 autologous oocyte cycles), of which 832 blastocysts were transferred. Intervention(s) No patient intervention. Embryos were cultured in a time-lapse monitoring system, and the embryos were transferred on day 5 after ICSI. Emb…

0301 basic medicinemedicine.medical_specialtyZygotemedicine.medical_treatmentBiologyTime-Lapse ImagingIntracytoplasmic sperm injectionAndrologyEmbryo Culture Techniques03 medical and health sciences0302 clinical medicinePregnancyImage Interpretation Computer-AssistedmedicineMorphogenesisHumansBlastocystEmbryo ImplantationSperm Injections Intracytoplasmicreproductive and urinary physiologyRetrospective StudiesGynecology030219 obstetrics & reproductive medicineZygoteurogenital systemEmbryogenesisObstetrics and GynecologyOocyteEmbryo TransferEmbryonic stem cellEmbryo transferKinetics030104 developmental biologymedicine.anatomical_structureBlastocystFertilityTreatment OutcomeReproductive MedicineSpainInfertilityembryonic structuresMultivariate AnalysisFemaleEmbryo qualityAlgorithmsFertility and sterility
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The human first cell cycle: impact on implantation.

2013

The morphology of fertilization events has been related to successful implantation by subjective criteria (pronuclei score, pronuclei symmetry and position). This work first described these events by time-lapse technology and then compared the timings of fertilization events (second polar body extrusion, first and second pronuclei appearance, abuttal and fading) in implanted versus nonimplanted embryos in a 2-year cohort retrospective study. A total of 1448 transferred embryos from 842 patients undergoing intracytoplasmic sperm injection with oocyte donation were monitored, 212 embryos from treatments where the number of gestational sacs matched the number of transferred embryos and 687 emb…

Pronucleusmedicine.medical_treatmentObstetrics and GynecologySecond polar bodyEmbryoBiologyCell cycleTime-Lapse ImagingIntracytoplasmic sperm injectionCell biologyAndrologyHuman fertilizationReproductive MedicinePregnancyembryonic structuresmedicineImage acquisitionGestationHumansFemaleEmbryo ImplantationSperm Injections IntracytoplasmicDevelopmental BiologyReproductive biomedicine online
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