0000000000022433

AUTHOR

Amelia Guadalupe-grau

0000-0003-2573-4572

showing 3 related works from this author

Repeated muscle biopsies through a single skin incision do not elicit muscle signaling, but IL-6 mRNA and STAT3 phosphorylation increase in injured m…

2011

To determine if muscle biopsies can be repeated using a single small (5–6 mm) skin incision without inducing immediate MAPK activation or inflammation in the noninjured areas, the phosphorylation of ERK1/2, p38-MAPK, c-Jun NH2-terminal kinases (JNKs), IκBα, IKKα, and signal transducer and activator of transcription 3 (STAT3) was examined concurrent with IL-6 mRNA in six muscle biopsies obtained from the vastus lateralis of five men. Four biopsies were obtained through the same incision (5–6 mm) from the right leg (taken at 0, 30, 123, and 126 min) and another two each from new incisions performed in the left leg (at 31 and 120 min), while the subjects rested supine. The first three biopsie…

AdultMaleSTAT3 Transcription FactorMAPK/ERK pathwaymedicine.medical_specialtyPathologyTime FactorsPhysiologyBiopsyInflammationp38 Mitogen-Activated Protein KinasesQuadriceps MuscleMuscular DiseasesNF-KappaB Inhibitor alphaPhysiology (medical)Internal medicinemedicineHumansRNA MessengerPhosphorylationSTAT3Interleukin 6Mitogen-Activated Protein Kinase 1Analysis of VarianceWound HealingMitogen-Activated Protein Kinase 3Skin incisionbiologyInterleukin-6JNK Mitogen-Activated Protein KinasesIl 6 mrnaI-kappa B KinaseUp-RegulationEndocrinologybiology.proteinSTAT proteinPhosphorylationI-kappa B Proteinsmedicine.symptomSignal TransductionJournal of Applied Physiology
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Endocrinology of Aging From a Muscle Function Point of View: Results From the Toledo Study for Healthy Aging.

2016

Aging is a process that involves a reduction in muscle strength and anabolic hormone concentrations, which impacts significantly on health.To study the hormone/total strength (H/TS) ratio as a proxy of anabolic insensitivity status in elders, and its relationship with disability, hospitalization, and mortality risk.A total of 1462 persons aged ≥65 years from the Toledo Study of Healthy Aging participated in this study. Serum concentrations of insulin like growth factor 1, total and free testosterone, dehydroepiandrosterone, dehydroepiandrosterone sulfate, and 17β-estradiol were measured. Total maximal voluntary isometric strength was obtained (handgrip, shoulder, hip, and knee) using standa…

0301 basic medicineMalemedicine.medical_specialtyAnabolismmedicine.medical_treatmentDehydroepiandrosteroneEndocrine SystemIsometric exercisePhysical strengthLogistic regressionHealthy Aging03 medical and health scienceschemistry.chemical_compoundInsulin-like growth factor0302 clinical medicineDehydroepiandrosterone sulfateInternal medicinemedicineHumans030212 general & internal medicineMuscle StrengthMuscle SkeletalGeneral NursingAgedbusiness.industryHealth PolicyMortality rateGeneral MedicineHospitalization030104 developmental biologyEndocrinologychemistrySpainFemaleGeriatrics and GerontologybusinessJournal of the American Medical Directors Association
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Comparative Analysis of the Effects of Daily Eating Habits and Physical Activity on Anthropometric Parameters in Elementary School Children in Latvia…

2020

Growing incidence of obesity and related diseases in children poses new challenges and calls for a review of lifestyle habits. This study aimed to assess daily eating habits (EH) and physical activity (PA) levels and identify their association with obesity in 8&ndash

MalePediatric ObesityCalorieWaiststructured physical activity030209 endocrinology & metabolismbody mass indexlcsh:TX341-641Diet SurveysArticle03 medical and health sciences0302 clinical medicinepupilsFood choiceMedicineHumans030212 general & internal medicineEating habitsChildStudentsExerciseNutrition and DieteticsSchoolsAnthropometrybusiness.industryIncidence (epidemiology)Body Weighteating habitsFeeding BehaviorAnthropometrymedicine.diseaseObesityLatviaBody HeightCross-Sectional Studieselementary schoolFemaleDiet HealthyWaist CircumferencebusinessBody mass indexlcsh:Nutrition. Foods and food supplyFood ScienceDemographyNutrients
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