“Fake it ‘til you make it”: The designer playground for crafting prototypes, orchestrating frauds and pushing the ecological transition

In the past thirty years, there has been a radical change in almost every business sector: companies nowadays offer increasingly complete packages or “bundles,” i.e-, combinations of goods, services, assistance, self-service and customer-focused knowledge. But it is services that have the lion’s share. In this context, those involved in the servitization process, such as designers, entrepreneurs, and venture capitalists, seem to focus more and more on the customer experience than on enabling technology. This has led to the birth of many successful new companies as well as to financial scandals. The aim of this article is to understand how the “fake ’til you make it” approach in design and b…

Comment intégrer les thématiques de l'environnement et les préceptes du développement durable dans une formation au service de la société ?

http://www.millenaire3.com/uploads/tx_ressm3/Actes_colloque_EEDD2004.pdfhttp://www.millenaire3.com/uploads/tx_ressm3/Actes_colloque_EEDD2004.pdf; International audience; 1. La formation des acteurs - Formation tout au long de la vie versus développement durable - Prise en compte de l' EDD dans la formation professionnelle : la formation comme vecteur du développement durable - Rôle des structures d'enseignement et de formation 2. Comment généraliser la prise en compte de la thématique environnement et de l'EEDD dans l'enseignement supérieur et la recherche!? 3. Quelques réflexions et propositions

Being the Family Caregiver of a Patient With Dementia During the Coronavirus Disease 2019 Lockdown

Background: Family caregivers of patients with dementia are at high risk of stress and burden, and quarantine due to the coronavirus disease 2019 (COVID-19) pandemic may have increased the risk of psychological disturbances in this population. The current study was carried out during the national lockdown declared in March 2020 by the Italian government as a containment measure of the first wave of the coronavirus pandemic and is the first nationwide survey on the impact of COVID-19 lockdown on the mental health of dementia informal caregivers.Methods: Eighty-seven dementia centers evenly distributed on the Italian territory enrolled 4,710 caregiver–patient pairs. Caregivers underwent a tel…

Dalla certificazione energetica alla sostenibilità ambientale degli edifici

Accuracy of the clinical diagnosis of dementia with Lewy bodies (DLB) among the Italian Dementia Centers: a study by the Italian DLB study group (DLB-SINdem)

Introduction: Dementia with Lewy bodies (DLB) may represent a diagnostic challenge, since its clinical picture overlaps with other dementia. Two toolkits have been developed to aid the clinician to diagnose DLB: the Lewy Body Composite Risk Score (LBCRS) and the Assessment Toolkit for DLB (AT-DLB). We aim to evaluate the reliability of these two questionnaires, and their ability to enhance the interpretation of the international consensus diagnostic criteria. Methods: LBCRS and AT-DLB were distributed to 135 Italian Neurological Centers for Cognitive Decline and Dementia (CDCDs), with the indication to administer them to all patients with dementia referred within the subsequent 3 months. We…

Effect of RNS60 in amyotrophic lateral sclerosis: a phase II multicentre, randomized, double-blind, placebo-controlled trial

Background and purpose: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with limited treatment options. RNS60 is an immunomodulatory and neuroprotective investigational product that has shown efficacy in animal models of ALS and other neurodegenerative diseases. Its administration has been safe and well tolerated in ALS subjects in previous early phase trials. Methods: This was a phase II, multicentre, randomized, double-blind, placebo-controlled, parallel-group trial. Participants diagnosed with definite, probable or probable laboratory-supported ALS were assigned to receive RNS60 or placebo administered for 24 weeks intravenously (375 ml) once a week and via nebul…

Sistemi di rappresentazione virtuale integrata e suoi applicativi: il caso di Piazza Croci a Palermo

Gli studi più aggiornati sulla percezione dello spazio mediante dispositivi di visualizzazione digitale hanno incrementato esponenzialmente le esperienze in questo ramo di ricerca applicata. Nel tentativo di proporre un’utile ricerca applicativa delle tecnologie di rappresentazione digitale si è provato a sperimentare a Palermo un prototipo di “Hyper-City” calato su un ristretto campo di indagine. La scelta dell’area di sperimentazione è ricaduta su un noto sito urbano della città di Palermo: piazza Francesco Crispi. Per l’importanza storica che contraddistingue la sua stratificazione urbanistica, per l’importanza artistica degli oggetti architettonici che l’hanno circoscritta e che in mini…

The Italian dementia with Lewy bodies study group (DLB-SINdem): toward a standardization of clinical procedures and multicenter cohort studies design

Dementia with Lewy bodies (DLB) causes elevated outlays for the National Health Systems due to high institutionalization rate and patients' reduced quality of life and high mortality. Furthermore, DLB is often misdiagnosed as Alzheimer's disease. These data motivate harmonized multicenter longitudinal cohort studies to improve clinical management and therapy monitoring. The Italian DLB study group of the Italian Neurological Society for dementia (SINdem) developed and emailed a semi-structured questionnaire to 572 national dementia centers (from primary to tertiary) to prepare an Italian large longitudinal cohort. The questionnaire surveyed: (1) prevalence and incidence of DLB; (2) clinical…