0000000000023247

AUTHOR

Maria Gabriella Schimmenti

showing 2 related works from this author

Investigation and management of Toxoplasma gondii infection in pregnancy and infancy: a prospective study.

2011

Aim:Toxoplasma gondii infection during pregnancy poses a serious risk to the fetus, therefore timely and accurate diagnosis is essential. The aim of this study was to estimate the frequency of congenital infection via evaluating mother's immunological status and the possibility to improving the diagnostic and therapeutic approaches.Methods:Eighty five mothers with Toxoplasma seroconversion and their offspring were enrolled (among them, 2 spontaneous abortions were documented in the first trimester). Prenatal PCR diagnosis was carried out on 50 patients (60%), with 7 positive cases (14%). Morphological ultrasound scanning revealed anomalies in one fetus. Long-term follow-up included general …

medicine.medical_specialtySettore MED/17 - Malattie InfettiveOffspringToxoplasmosis gondiineurological prognosiToxoplasmosis CongenitalSerologySettore MED/38 - Pediatria Generale E SpecialisticaPregnancyPrenatal DiagnosismedicineHumansPharmacology (medical)Prospective StudiesSeroconversionProspective cohort studyChildPharmacologyFetusPregnancybiologybusiness.industryObstetricsSettore MED/30 - Malattie Apparato Visivoocular prognosiPregnancy OutcomeToxoplasma gondiiGeneral Medicinemedicine.diseasebiology.organism_classificationToxoplasmosisInfectious Disease Transmission Verticalcongenital infectionWestern blot analysisprenatal screeningChild PreschoolPregnancy Complications ParasiticImmunologyserological responseFemaleOriginal ArticlebusinessFollow-Up StudiesActa pharmacologica Sinica
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Epidemiology of Toxoplasma and CMV serology and of GBS colonization in pregnancy and neonatal outcome in a Sicilian population

2013

Background: Aim of our study is to analyze the immunological status in pregnancy for two main TORCH agents, Toxoplasma and Cytomegalovirus (CMV), and the results of group B streptococcus (GBS) screening, assessing the risk for congenital infection in a population from Palermo, Italy. Methods: We retrospectively analyzed the medical records of all inborn live newborns who were born in our division during 2012, gathering information about the mother, the pregnancy and neonatal hospitalization at birth. Whenever data were available, we categorized the serologic status of the mothers for Toxoplasma and CMV. We also considered the results of rectal and vaginal swabs for GBS. We compared the resu…

MaleEpidemiologyAntibodies ProtozoanCytomegalovirusmedicine.disease_causeAntibodies ViralGroup BInfant Newborn DiseasesSerologySettore MED/38 - Pediatria Generale E SpecialisticaPregnancyRisk FactorsPrenatal DiagnosisEpidemiologyPrevalencePregnancy Complications InfectiousIntrauterine infectionSicilyeducation.field_of_studyPregnancy OutcomeCMVMiddle AgedAntibodies BacterialAntibodies Anti-IdiotypicCytomegalovirus InfectionsFemaleToxoplasmaToxoplasmosisAdultmedicine.medical_specialtyAdolescentPopulationCongenital cytomegalovirus infectionGBSRisk AssessmentStreptococcus agalactiaeYoung AdultStreptococcal InfectionsmedicineAnimalsHumanseducationRetrospective StudiesPregnancybusiness.industryResearchInfant Newbornmedicine.diseaseToxoplasmosisStreptococcus agalactiaeImmunoglobulin GImmunologybusinessItalian Journal of Pediatrics
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