0000000000025719
AUTHOR
L. Di Martino
The conservation of the endemic Crop Wild Relatives in the RIBES seed-banks: towards a national priority list for the Italian CWRs
Data of 620 crop wild relatives of species of food and fodder interest listed in the Annex I of the FAO Treaty (FAO, 2001) were collected within the census carried out by ISPRA, the Italian National Institute for Environmental Protection and Research, in 2014-2015 in order to quantify the extent of CWR representation in the Italian ex situ collections. According to such census, the RIBES network preserve 37% of the Italian CWRs listed in the FAO Treaty: in 14 out of 16 seed-banks are preserved 6,029 accessions of 229 CWR taxa, belonging to 11 families and 57 genera.
The SISV support to the implementation of a national manual for monitoring the Habitats of the 92/43/EEC Directive in Italy.
The 4th National Report ex Art. 17 of the 92/43/EEC Directive in Italy (period 2013-2018) will try to fill a number of gaps still affecting the former versions of the Italian Reports, where territorial data were still missing for large parts of the country and the assessment was mostly based on the use of the expert opinion. Similar inconsistencies also emerged in other European countries (State of nature in the EU, EEA 2015). In order to reach this aim, a nationally shared protocol for monitoring the vegetation-based Annex I Habitats is currently under development. The most prominent issues addressed by the ongoing project are: i) fixing standardized, updated and scientifically grounded me…
First overview on the 4th Annex I Habitats Report in Italy: methods, criticality, results and future prospects
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TREATMENT OF VISCERAL LEISHMANIASIS IN CHILDREN USING LIPOSOMAL AMPHOTHERICIN B
We used liposomal amphotericin B as first-choice treatment of visceral leishmaniasis in 106 immunocompetent children who acquired the infection in a temperate region of southern Europe (Italy) where Leishmania infantum visceral leishmaniasis is endemic. The aim of the study was to identify the minimum total dose of liposomal amphotericin B needed to cure the infection in children and reduce the period of hospitalization. We conclude that the optimal regimen in immunocompetent children with L. infantum visceral leishmaniasis to be a total dose of 18 mg/kg of liposomal amphotericin B (3 mg/kg per day for 5 days, followed by 3 mg/kg administered as an outpatient regimen on day 10).
Short-course treatment of visceral leishmaniasis with liposomal amphotericin B (AmBisome).
We evaluated liposomal amphotericin B (AmBisome; Vestar, San Dimas, CA) administered to 88 immunocompetent patients (56 children) with visceral leishmaniasis (VL) caused by Leishmania infantum. Thirteen patients received 4 mg/kg on days 1-5 and 10 (total dose, 24 mg/kg), and all were cured; 42 received 3 mg/kg on days 1-5 and 10 (18 mg/kg), and 41 were cured; 32 received 3 mg/kg on days 1-4 and 10 (15 mg/kg), and 29 were cured (amastigotes were not cleared from 1 child, and 2 relapsed). One adult was cured with a total dose of 12mg/kg. The four children who were not cured received 3 mg/kg for 10 days; none had further relapses. There were no significant adverse events. For VL due to L. infa…