0000000000027596

AUTHOR

X. Han

Corrigendum to “Premature ovarian senescence and a high miscarriage rate impair fertility in women with HCV” [J Hepatol 68 (2018) 33–41](S0168827817322596)(10.1016/j.jhep.2017.08.019)

It has come to our attention that the PITER framework investigator, Alessandro Federico, was incorrectly listed as F. Alessandro in the original manuscript. Please note that the correct name of this author is Alessandro Federico (2nd University of Naples). The correct list of PITER investigators is in the footnote below.

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Increased mRNAs for procollagens and key regulating enzymes in rat skeletal muscle following downhill running.

The purpose of the study was to investigate pre-translational regulation of collagen expression after a single bout of exercise. We analysed steady-state messenger ribonucleic acid (mRNA) levels for collagen types I, III and IV, alpha- and beta-subunits of prolyl 4-hydroxylase and lysyl oxidase (enzymes modifying procollagen chains), and enzyme activity of prolyl 4-hydroxylase from rat soleus muscle (MS) and the red parts of quadriceps femoris muscle (MQF) after 12 h and after 1, 2, 4, 7 and 14 days of downhill (-13.5 degrees ) treadmill running at a speed of 17 m.min-1 for 130 min. Histological and biochemical assays revealed exercise-induced muscle damage in MQF but not MS. Steady-state m…

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First observation of the doubly charmed baryon decay Ξcc++→Ξc+π+

The doubly charmed baryon decay Ξcc++→Ξc+π+ is observed for the first time, with a statistical significance of 5.9σ, confirming a recent observation of the baryon in the Λc+K−π+π+ final state. The data sample used corresponds to an integrated luminosity of 1.7 fb−1, collected by the LHCb experiment in pp collisions at a center-of-mass energy of 13 TeV. The Ξcc++ mass is measured to be 3620.6±1.5(stat)±0.4(syst)±0.3(Ξc+) MeV/c2 and is consistent with the previous result. The ratio of branching fractions between the decay modes is measured to be [B(Ξcc++→Ξc+π+)×B(Ξc+→pK−π+)]/[B(Ξcc++→Λc+K−π+π+)×B(Λc+→pK−π+)]=0.035±0.009(stat)±0.003(syst).

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First Observation ofD0−D¯0Oscillations inD0→K+π−π+π−Decays and Measurement of the Associated Coherence Parameters

Charm meson oscillations are observed in a time-dependent analysis of the ratio of D0→K+π−π+π− to D0→K−π+π−π+ decay rates, using data corresponding to an integrated luminosity of 3.0fb−1 recorded by the LHCb experiment. The measurements presented are sensitive to the phase-space averaged ratio of doubly Cabibbo-suppressed to Cabibbo-favoured amplitudes rK3πD and the product of the coherence factor RK3πD and a charm mixing parameter y′K3π. The constraints measured are rK3πD=(5.67±0.12)×10−2, which is the most precise determination to date, and RK3πD⋅y′K3π=(0.3±1.8)×10−3, which provides useful input for determinations of the CP-violating phase γ in B±→DK±,D→K∓π±π∓π± decays. The analysis also …

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First Observation of Top Quark Production in the Forward Region

Top quark production in the forward region in proton-proton collisions is observed for the first time. The W + b final state with W → μν is reconstructed using muons with a transverse momentum, p[subscript T], larger than 25 GeV in the pseudorapidity range 2.0 20  GeV. The results are based on data corresponding to integrated luminosities of 1.0 and 2.0  fb[superscript -1] collected at center-of-mass energies of 7 and 8 TeV by LHCb. The inclusive top quark production cross sections in the fiducial region are σ(top)[7  TeV] = 239 ± 53(stat) ± 33(syst) ± 24(theory)  fb, σ(top)[8  TeV] = 289 ± 43(stat) ± 40(syst) ± 29(theory)  fb.These results, along with the observed differential yields and c…

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Study of W Boson Production in Association with Beauty and Charm

The associated production of a W boson with a jet originating from either a light parton or heavy-flavor quark is studied in the forward region using proton-proton collisions. The analysis uses data corresponding to integrated luminosities of 1.0 and 2.0  fb[superscript -1] collected with the LHCb detector at center-of-mass energies of 7 and 8 TeV, respectively. The W bosons are reconstructed using the W → μν decay and muons with a transverse momentum, p[subscript T], larger than 20 GeV in the pseudorapidity range 2.0 20  GeV and 2.2 20  GeV. The fraction of W + jet events that originate from beauty and charm quarks is measured, along with the charge asymmetries of the W + b and W + c produ…

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Measurement of the chi(b) (3 P) mass and of the relative rate of chi(b1) (1 P) and chi(b2) (1 P) production

The production of $\chi_b$ mesons in proton-proton collisions is studied using a data sample collected by the LHCb detector, at centre-of-mass energies of $\sqrt{s}=7$ and $8$ TeV and corresponding to an integrated luminosity of 3.0 fb$^{-1}$. The $\chi_b$ mesons are identified through their decays to $\Upsilon(1S)\gamma$ and $\Upsilon(2S)\gamma$ using photons that converted to $e^+e^-$ pairs in the detector. The $\chi_b(3P)$ meson mass, and the relative prompt production rate of $\chi_{b1}(1P)$ and $\chi_{b2}(1P)$ mesons as a function of the $\Upsilon(1S)$ transverse momentum in the $\chi_b$ rapidity range 2.0< $y$<4.5, are measured. Assuming a mass splitting between the $\chi_{b1}(3P)$ an…

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Updated determination of D0–D¯0 mixing and CP violation parameters with D0→K+π− decays

We report measurements of charm-mixing parameters based on the decay-time-dependent ratio of D0→K+π- to D0→K-π+ rates. The analysis uses a data sample of proton-proton collisions corresponding to an integrated luminosity of 5.0  fb-1 recorded by the LHCb experiment from 2011 through 2016. Assuming charge-parity (CP) symmetry, the mixing parameters are determined to be x′2=(3.9±2.7)×10-5, y′=(5.28±0.52)×10-3, and RD=(3.454±0.031)×10-3. Without this assumption, the measurement is performed separately for D0 and D¯0 mesons, yielding a direct CP-violating asymmetry AD=(-0.1±9.1)×10-3, and magnitude of the ratio of mixing parameters 1.00<|q/p|<1.35 at the 68.3% confidence level. All results incl…

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mRNA levels for α-subunit of prolyl 4-hydroxylase and fibrillar collagens in immobilized rat skeletal muscle

There is evidence that immobilization causes a decrease in total collagen synthesis in skeletal muscle within a few days. In this study, early immobilization effects on the expression of prolyl 4-hydroxylase (PH) and the main fibrillar collagens at mRNA and protein levels were investigated in rat skeletal muscle. The right hindlimb was immobilized in full plantar flexion for 1, 3, and 7 days. Steady-state mRNAs for α- and β-subunits of PH and type I and III procollagen, PH activity, and collagen content were measured in gastrocnemius and plantaris muscles. Type I and III procollagen mRNAs were also measured in soleus and tibialis anterior muscles. The mRNA level for the PH α-subunit decreas…

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Observation of charmonium pairs produced exclusively in $pp$ collisions

A search is performed for the central exclusive production of pairs of charmonia produced in proton-proton collisions. Using data corresponding to an integrated luminosity of $3{\rm\ fb}^{-1}$ collected at centre-of-mass energies of 7 and 8 TeV, $J/\psi J/\psi$ and $J/\psi\psi(2S)$ pairs are observed, which have been produced in the absence of any other activity inside the LHCb acceptance that is sensitive to charged particles in the pseudorapidity ranges $(-3.5,-1.5)$ and $(1.5,5.0)$. Searches are also performed for pairs of P-wave charmonia and limits are set on their production. The cross-sections for these processes, where the dimeson system has a rapidity between 2.0 and 4.5, are measu…

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Major results from the first plasma campaign of the Wendelstein 7-X stellarator

After completing the main construction phase of Wendelstein 7-X (W7-X) and successfully commissioning the device, first plasma operation started at the end of 2015. Integral commissioning of plasma start-up and operation using electron cyclotron resonance heating (ECRH) and an extensive set of plasma diagnostics have been completed, allowing initial physics studies during the first operational campaign. Both in helium and hydrogen, plasma breakdown was easily achieved. Gaining experience with plasma vessel conditioning, discharge lengths could be extended gradually. Eventually, discharges lasted up to 6 s, reaching an injected energy of 4 MJ, which is twice the limit originally agreed for t…

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Measurement of CP asymmetry in D 0 → K - K + and D 0 → π - πdecays

Time-integrated $CP$ asymmetries in $D^0$ decays to the final states $K^- K^+$ and $\pi^- \pi^+$ are measured using proton-proton collisions corresponding to $3\mathrm{\,fb}^{-1}$ of integrated luminosity collected at centre-of-mass energies of $7\mathrm{\,Te\kern -0.1em V}$ and $8\mathrm{\,Te\kern -0.1em V}$. The $D^0$ mesons are produced in semileptonic $b$-hadron decays, where the charge of the accompanying muon is used to determine the initial flavour of the charm meson. The difference in $CP$ asymmetries between the two final states is measured to be \begin{align} \Delta A_{CP} = A_{CP}(K^-K^+)-A_{CP}(\pi^-\pi^+) = (+0.14 \pm 0.16\mathrm{\,(stat)} \pm 0.08\mathrm{\,(syst)})\% \ . \nonu…

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Observation of charmless baryonic decays B(s)0→pp¯h+h′−

Decays of B0 and Bs0 mesons to the charmless baryonic final states pp¯h+h′-, where h and h′ each denote a kaon or a pion, are searched for using the LHCb detector. The analysis is based on a sample of proton-proton collision data collected at center-of-mass energies of 7 and 8 TeV, corresponding to an integrated luminosity of 3  fb-1. Four-body charmless baryonic Bs0 decays are observed for the first time. The decays Bs0→pp¯K+K-, Bs0→pp¯K±π∓, B0→pp¯K±π∓ and B0→pp¯π+π- are observed with a significance greater than 5 standard deviations; evidence at 4.1 standard deviations is found for the B0→pp¯K+K- decay and an upper limit is set on the branching fraction for Bs0→pp¯π+π-. Branching fraction…

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Measurement of CP asymmetry in Bs0 → Ds ∓K± decays

Journal of high energy physics 2018(3), 59 (2018). doi:10.1007/JHEP03(2018)059

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Search for Structure in theBs0π±Invariant Mass Spectrum

The $B_s^0\pi^\pm$ invariant mass distribution is investigated in order to search for possible exotic meson states. The analysis is based on a data sample recorded with the LHCb detector corresponding to $3$ fb$^{-1}$ of $pp$ collision data at $\sqrt{s} = 7$ and $8$ TeV. No significant excess is found, and upper limits are set on the production rate of the claimed $X(5568)$ state. Upper limits are also set as a function of the mass and width of a possible exotic meson decaying to the $B_s^0\pi^\pm$ final state.

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Observation of $Z$ production in proton-lead collisions at LHCb

The first observation of $Z$ boson production in proton-lead collisions at a centre-of-mass energy per proton-nucleon pair of $\sqrt{s_{NN}}=5~\text{TeV}$ is presented. The data sample corresponds to an integrated luminosity of $1.6~\text{nb}^{-1}$ collected with the LHCb detector. The $Z$ candidates are reconstructed from pairs of oppositely charged muons with pseudorapidities between 2.0 and 4.5 and transverse momenta above $20~\text{GeV}/c$. The invariant dimuon mass is restricted to the range $60-120~\text{GeV}/c^2$. The $Z$ production cross-section is measured to be \begin{eqnarray*} ��_{Z\to��^+��^-}(\text{fwd})&amp;=&amp;13.5^{+5.4}_{-4.0}\text{(stat.)}\pm1.2\text{(syst.)}~\text{nb} …

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Evidence for Exotic Hadron Contributions toΛb0→J/ψpπ−Decays

A full amplitude analysis of $\Lambda_b^0 \to J/\psi p \pi^-$ decays is performed with a data sample acquired with the LHCb detector from 7 and 8 TeV $pp$ collisions, corresponding to an integrated luminosity of 3 fb$^{-1}$. A significantly better description of the data is achieved when, in addition to the previously observed nucleon excitations $N\to p\pi^-$, either the $P_c(4380)^+$ and $P_c(4450)^+\to J/\psi p$ states, previously observed in $\Lambda_b^0 \to J/\psi p K^-$ decays, or the $Z_c(4200)^-\to J/\psi \pi^-$ state, previously reported in $B^0 \to J/\psi K^+ \pi^-$ decays, or all three, are included in the amplitude models. The data support a model containing all three exotic sta…

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Collagens in the injured porcine intervertebral disc

Spinal pain often is thought to be due to degeneration and mechanical failure of the intervertebral disc. Since the mechanical strength of the tissue depends on collagen fibers, the present study was designed to investigate the reactions in collagen metabolism after an experimentally induced disc injury. Five domestic pigs underwent an incision in the anterior part of the annulus fibrosus of disc L4-L5 through a retroperitoneal approach. The animals were killed 3 months postoperatively, and the injured discs and intact discs (controls) from different animals were removed for chemical analysis. Slices were cut from seven different parts across the disc. The concentration of total collagen (h…

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Differential branching fractions and isospin asymmetries of B -> K ((*)) μ(+) μ(-) decays

The isospin asymmetries of $B \to K\mu^+\mu^-$ and $B \to K^{*}\mu^+\mu^-$ decays and the partial branching fractions of the $B^0 \to K^0\mu^+\mu^-$, $B^+ \to K^+\mu^+\mu^-$ and $B^+ \to K^{*+}\mu^+\mu^-$ decays are measured as functions of the dimuon mass squared, $q^2$. The data used correspond to an integrated luminosity of 3$~$fb$^{-1}$ from proton-proton collisions collected with the LHCb detector at centre-of-mass energies of 7$\,$TeV and 8$\,$TeV in 2011 and 2012, respectively. The isospin asymmetries are both consistent with the Standard Model expectations. The three measured branching fractions, while individually consistent, all favour lower values than their respective Standard M…

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Pre- and Post-translational Regulation of Lysyl Oxidase by Transforming Growth Factor-β1 in Osteoblastic MC3T3-E1 Cells

The final enzymatic step required for collagen cross-linking is the extracellular oxidative deamination of peptidyl-lysine and -hydroxylysine residues by lysyl oxidase. A cross-linked collagenous extracellular matrix is required for bone formation. The goals of this study were to compare the transforming growth factor (TGF)-beta 1 regulation of lysyl oxidase enzyme activity and steady state mRNA levels to changes in COL1A1 mRNA levels in MC3T3-E1 osteoblastic cells. TGF-beta 1 increased steady state lysyl oxidase and COL1A1 mRNA levels in a dose- and time-dependent manner. The increase in lysyl oxidase mRNA levels was transient, peaking at 12 h and 8.8 times controls in cells treated with 4…

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Studies of the resonance structure inD0→KS0K±π∓decays

Amplitude models are constructed to describe the resonance structure of D0→ K-π+π+π- and D0→ K+π-π-π+ decays using pp collision data collected at centre-of-mass energies of 7 and 8 TeV with the LHCb experiment, corresponding to an integrated luminosity of 3.0 fb- 1. The largest contributions to both decay amplitudes are found to come from axial resonances, with decay modes D0→ a1(1260) +K- and D0→ K1(1270 / 1400) +π- being prominent in D0→ K-π+π+π- and D0→ K+π-π-π+, respectively. Precise measurements of the lineshape parameters and couplings of the a1(1260) +, K1(1270) - and K(1460) - resonances are made, and a quasi model-independent study of the K(1460) - resonance is performed. The coher…

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Overview of first Wendelstein 7-X high-performance operation

Abstract The optimized superconducting stellarator device Wendelstein 7-X (with major radius , minor radius , and plasma volume) restarted operation after the assembly of a graphite heat shield and 10 inertially cooled island divertor modules. This paper reports on the results from the first high-performance plasma operation. Glow discharge conditioning and ECRH conditioning discharges in helium turned out to be important for density and edge radiation control. Plasma densities of with central electron temperatures were routinely achieved with hydrogen gas fueling, frequently terminated by a radiative collapse. In a first stage, plasma densities up to were reached with hydrogen pellet injec…

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Search for weakly decaying b -flavored pentaquarks

Investigations of the existence of pentaquark states containing a single $b$ (anti)quark decaying weakly into four specific final states J/$\psi K^+\pi^- p$, J/$\psi K^- \pi^- p$, J/$\psi K^- \pi^+ p$, and $J/\psi \phi (1020) p$ are reported. The data sample corresponds to an integrated luminosity of 3.0/fb in 7 and 8 TeV pp collisions acquired with the LHCb detector. Signals are not observed and upper limits are set on the product of the production cross section times branching fraction with respect to that of the $\Lambda_b$.

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Determination of γ and−2βsfrom charmless two-body decays of beauty mesons

Using the latest LHCb measurements of time-dependent CP violation in the B-s(0) -> K+K- decay, a U-spin relation between the decay amplitudes of B-s(0) -> K+K- and B-0 -> p(+)p(-) decay processes allows constraints to be placed on the angle gamma of the unitarity triangle and on the B-s(0) mixing phase -2 beta(s). Results from an extended approach, which uses additional inputs on B-0 -> pi(0)pi(0) and B+ -> pi(+)pi(0) decays from other experiments and exploits isospin symmetry, are also presented. The dependence of the results on the maximum allowed amount of U-spin breaking is studied. At 68% probability, the value gamma =( 63.5(-6.7)(+7.2))degrees modulo 180 degrees is determined. In an a…

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Right ventricular collagen type III and IV gene expression increases during early phases of endurance training in hypobaric hypoxic condition

The objective of this study was to examine the effects of prolonged exposure to hypobaric hypoxic condition, physical training and their combination on collagen type I, III and IV gene expression in the ventricles and atria of rat heart. Male rats were assigned to four groups: normobaric sedentary (NS) and trained (NT), and hypobaric sedentary (HS) and trained (HT). Exposure to and treadmill running training in hypobaric condition were carried out in a hypobaric chamber (770–740 mbar, 2250–2550 m). Experimental periods were 10, 21 and 56 days; the groups of 91 days served as recovery groups from experimental settings of 56 days. Exposure to hypobaric condition as such and in combination wit…

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Measurement of the branching fraction of the decay Bs0→KS0KS0

A measurement of the branching fraction of the decay Bs0→KS0KS0 is performed using proton-proton collision data corresponding to an integrated luminosity of 5 fb-1 collected by the LHCb experiment between 2011 and 2016. The branching fraction is determined to be B(Bs0→KS0KS0)=[8.3±1.6(stat)±0.9(syst)±0.8(norm)±0.3(fs/fd)]×10-6, where the first uncertainty is statistical, the second is systematic, and the third and fourth are due to uncertainties on the branching fraction of the normalization mode B0→φKS0 and the ratio of hadronization fractions fs/fd. This is the most precise measurement of this branching fraction to date. Furthermore, a measurement of the branching fraction of the decay B0…

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Skeletal Muscle Collagen Type 1 mRNA, Prolyl-4-Hydroxylase and Hydroxyproline after Prolonged Physical Training in Hypobaric Hypoxia

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Measurement of the c0 Baryon Lifetime

We report a measurement of the lifetime of the $��_c^0$ baryon using proton-proton collision data at center-of-mass energies of 7 and 8~TeV, corresponding to an integrated luminosity of 3.0 fb$^{-1}$ collected by the LHCb experiment. The sample consists of about 1000 $��_b^-\to��_c^0��^-\bar��_�� X$ signal decays, where the $��_c^0$ baryon is detected in the $pK^-K^-��^+$ final state and $X$ represents possible additional undetected particles in the decay. The $��_c^0$ lifetime is measured to be $��_{��_c^0} = 268\pm24\pm10\pm2$ fs, where the uncertainties are statistical, systematic, and from the uncertainty in the $D^+$ lifetime, respectively. This value is nearly four times larger than, …

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Measurement of CP asymmetries in the decays B0 → K*0 μ+μ- and B+ → K+ μ+μ-

The direct CP asymmetries of the decays B 0 → K *0 μ + μ − and B + → K + μ + μ − are measured using pp collision data corresponding to an integrated luminosity of 3.0 fb−1 collected with the LHCb detector. The respective control modes B 0 → J/ψK *0 and B + → J/ψK + are used to account for detection and production asymmetries. The measurements are made in several intervals of μ + μ − invariant mass squared, with the ϕ(1020) and charmonium resonance regions excluded. Under the hypothesis of zero CP asymmetry in the control modes, the average values of the asymmetries are ACP(B0→K∗0μ+μ−)=−0.035±0.024±0.003,ACP(B+→K+μ+μ−)=0.012±0.017±0.001, where the first uncertainties are statistical and the …

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Effects of streptozotocin-induced diabetes, physical training and their combination on collagen biosynthesis in rat skeletal muscle.

The effects of streptozotocin-induced diabetes, physical training and their combination on the activities of prolyl 4-hydroxylase (PH) and galactosylhydroxylysyl glucosyl-transferase (GGT), both marker enzymes of collagen biosynthesis, and on the concentration of hydroxyproline (Hyp) were studied in vastus lateralis, rectus femoris and gastrocnemius muscles in rats. The experimental period was 12-16 weeks. Diabetes had an overall decreasing effect on specific PH activity in all muscles studied, whereas specific GGT activity remained at control level. Total PH and GGT activities decreased in all three muscles in the diabetic animals (P < 0.001). Training caused an increase in PH and GGT acti…

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Constraints on the unitarity triangle angleγfrom Dalitz plot analysis ofB0→DK+π−decays

The first study is presented of CP violation with an amplitude analysis of the Dalitz plot of B0→DK+π- decays, with D→K+π-, K+K-, and π+π-. The analysis is based on a data sample corresponding to 3.0 fb-1 of pp collisions collected with the LHCb detector. No significant CP violation effect is seen, and constraints are placed on the angle γ of the unitarity triangle formed from elements of the Cabibbo-Kobayashi-Maskawa quark mixing matrix. Hadronic parameters associated with the B0→DK∗(892)0 decay are determined for the first time. These measurements can be used to improve the sensitivity to γ of existing and future studies of the B0→DK∗(892)0 decay.

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Acute exercise induced changes in rat skeletal muscle mRNAs and proteins regulating type IV collagen content

This experiment tested the hypothesis that running-induced damage to rat skeletal muscle causes changes in synthesis and degradation of basement membrane type IV collagen and to proteins regulating its degradation. Samples from soleus muscle and red and white parts of quadriceps femoris muscle (MQF) were collected 6 h or 1, 2, 4, or 7 days after downhill running. Increased muscle β-glucuronidase activity indicated greater muscle damage in the red part of MQF than in the white part of MQF or soleus. In the red part of MQF, type IV collagen expression was upregulated at the pretranslational level and the protein concentration decreased, whereas matrix metalloproteinase-2 (MMP-2), a protein th…

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Genome-wide association meta-analysis of corneal curvature identifies novel loci and shared genetic influences across axial length and refractive error

Corneal curvature, a highly heritable trait, is a key clinical endophenotype for myopia - a major cause of visual impairment and blindness in the world. Here we present a trans-ethnic meta-analysis of corneal curvature GWAS in 44,042 individuals of Caucasian and Asian with replication in 88,218 UK Biobank data. We identified 47 loci (of which 26 are novel), with population-specific signals as well as shared signals across ethnicities. Some identified variants showed precise scaling in corneal curvature and eye elongation (i.e. axial length) to maintain eyes in emmetropia (i.e. HDAC11/FBLN2 rs2630445, RBP3 rs11204213); others exhibited association with myopia with little pleiotropic effects …

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Search for CP violation using T-odd correlations in D-0 -> K+K-pi(+)pi(-) decays

A search for $CP$ violation using $T$-odd correlations is performed using the four-body $D^0 \to K^+K^-\pi^+\pi^-$ decay, selected from semileptonic $B$ decays. The data sample corresponds to integrated luminosities of $1.0\,\text{fb}^{-1}$ and $2.0\,\text{fb}^{-1}$ recorded at the centre-of-mass energies of 7 TeV and 8 TeV, respectively. The $CP$-violating asymmetry $a_{CP}^{T\text{-odd}}$ is measured to be $(0.18\pm 0.29\text{(stat)}\pm 0.04\text{(syst)})\%$. Searches for $CP$ violation in different regions of phase space of the four-body decay, and as a function of the $D^0$ decay time, are also presented. No significant deviation from the $CP$ conservation hypothesis is found.

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First study of the CP-violating phase and decay-width difference in Bs0→ψ(2S)ϕ decays

A time-dependent angular analysis of Bs0→ψ(2S)ϕ decays is performed using data recorded by the LHCb experiment. The data set corresponds to an integrated luminosity of 3.0fb−1 collected during Run 1 of the LHC. The CP-violating phase and decay-width difference of the Bs0 system are measured to be ϕs=0.23−0.28+0.29±0.02rad and ΔΓs=0.066−0.044+0.041±0.007ps−1, respectively, where the first uncertainty is statistical and the second systematic. This is the first time that ϕs and ΔΓs have been measured in a decay containing the ψ(2S) resonance.

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Physical Exercise Increases mRNA Levels of Fibrillar Collagen Types I and Iii and α-Subunit of Prolyl 4-Hydroxylase in Rat Skeletal Muscle

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Measurements of charm mixing and CP violation using D0→K±π∓ decays

Measurements of charm mixing and CP violation parameters from the decay-time-dependent ratio of D0→K+π− to D0→K−π+ decay rates and the charge-conjugate ratio are reported. The analysis uses B¯¯¯¯→D∗+μ−X, and charge-conjugate decays, where D∗+→D0π+, and D0→K∓π±. The pp collision data are recorded by the LHCb experiment at center-of-mass energies s√ = 7 and 8 TeV, corresponding to an integrated luminosity of 3 fb−1. The data are analyzed under three hypotheses: (i) mixing assuming CP symmetry, (ii) mixing assuming no direct CP violation in the Cabibbo-favored or doubly Cabibbo-suppressed decay amplitudes, and (iii) mixing allowing either direct CP violation and/or CP violation in the superpos…

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