0000000000033490
AUTHOR
D. Jung
TALISMAN: Eine Softwareumgebung für die interaktive Verarbeitung medizinischer Bildserien
Fur die kardiologische Diagnostik eroffnen sich durch die interaktive Auswertung digitalisierter Bildserien zahlreiche neue Moglichkeiten. Die entstehenden Hardware- und Softwaresystem sind interaktiv zu erproben und unterliegen einer schnellen Entwicklung und Veranderung der Algorithmen und der Benutzeroberflachen. Die TALISMAN- Softwareumgebung erleichtert diese Vorgange durch folgende Eigenschaften: 1. Unterstutzung eines modularen Aufbaus der Anwendungsprogramme durch Bereitstellung eines Botschaftensystems (vgl. objektorientierte Umgebungen wie z. B. Smalltalk). 2. Standardisierung der Struktur der bildverarbeitenden Programm-Module (z.B. Daten-struktur und visuelle Darstellung der Bot…
Aktuelle Komplikationsrate der perkutanen transluminalen Koronarangioplastie bei stabiler und unstabiler Angina
During a four-year period (1983-1986) percutaneous transluminal coronary angioplasty (PTCA) was performed on 930 patients with stable or unstable angina with a mortality rate of 0.4%. A transmural myocardial infarct developed in 1.1% and 1.0% of patients required an urgent aorto-coronary bypass. Thus the total rate of severe cardiac complications was 2.5%. Compared with the years 1983-1985, there was in 1986 a significant fall in the number of deaths and of myocardial infarcts from 2.2% to 0.5% (P less than 0.05), while there was a nonsignificant increase in emergency coronary bypass surgery from 0.7 to 1.3%. Patients with unstable angina compared with those with stable angina had a signifi…
Structural dissimilarities in different regions of the pineal gland of Pirbright white guinea-pigs.
In the present study, the proximal, intermediate and distal parts of dumbbell-shaped pineal glands of Pirbright White guinea-pigs were investigated with respect to structural dissimilarities. The most conspicuous difference was that while in the proximal part the pinealocytes were arranged in a random fashion, the intermediate and distal regions, except a small ventral area in the latter, exhibited a prominent follicular arrangement of the pinealocytes. Concretions were restricted to the subcapsular region of the intermediate part, whereas cells with hyperchromatic nuclei increased in number in an anterior-posterior direction. In males, pinealocyte nuclear size did not differ significantly …
Cranial nerve function in workers exposed to polychlorinated dioxins and furans
OBJECTIVE: To look for possible effects of polychlorinated dioxins and furans (PCDD/F) on cranial nerve function. MATERIAL AND METHODS: Clinical and neurophysiological examinations [visual and brainstem auditory evoked potentials (VEP and BAEP), blink reflex] in 121 PCDD/F exposed workers of one pesticide producing plant. RESULTS: BAEP abnormalities were more frequent in workers with chloracne (6 of 33 workers, 18.2%) than in those without chloracne (7 of 84, 8.3%), but this was not statistically significant (chi2: 2.33). VEP abnormalities were seen in one worker with and two without chloracne. Clinically visual functions were normal except in one worker, who was amaurotic since birth. Blin…
Color superposition: a new modality for contrast echocardiography.
To improve the estimation of endocardial borders in echocardiography, a technique has been developed to combine images from contrasted and noncontrasted echocardiograms of the same heart-phase using a color superposition mode. This method allows both experienced as well as less experienced examiners to define the endocardial borders more reproducibly and objectively. This is achieved by displaying tissue structures as gray level images while the ventricular cavity is marked selectively by the color display of the contrast material zone. Results of volume estimations of the left ventricle by different examiners using several imaging modes including color superposition display are presented.
Quantitative Coronary Angiography and Digital Densitometric Perfusion Measurements?How to Assess the Success of Intracoronary Balloon Dilatation
Densitometric evaluation of digital subtraction angiocardiograms allows the assessment of local myocardial perfusion before and after pharmacological stimulation of coronary flow reserve during the catheterization procedure. This report deals with a case of a severe stenosis of the left coronary artery in which PTCA was regarded successful based on an appropriate increase in luminal diameter while an intima and media dissection at the dilatation site was documented. The perfusion measurements, however, pointed out a clear impairment of poststenotic myocardial perfusion after PTCA.
Comparison of Statistical Methods for the Detection of Contrast Material in Echocardiographic Image Sequences
Ultrasonic imaging of the heart is a diagnostic tool which is increasingly used in cardiology. In addition to the representation of important anatomical information two dimensional images provided by mechanical or electronically steered sector scanners can be used for the extraction of functional parameters of the heart (as e.g. enddiastolic volume or ejection fraction). A poor definition of the endocardial border especially resulting from the noisy appearance of the images and from qualitatively restricted echocardiograms leads to uncertainties in the quantitative analysis and therefore requires refined methods for the determination of functional parameters. Our investigations which are ba…
The effect of balloon dilatation on post-stenotic myocardial perfusion before and after stimulation of coronary flow reserve: evaluation by the densitometric parameter 'mean rise time'.
From densitometric evaluation of digital subtraction cineangiocardiograms the parameter 'Mean Rise Time' (MRT), defined as the time from the onset of local myocardial contrast medium opacification to the point of maximal opacification can be derived; this parameter revealed a close correlation with the results on myocardial perfusion obtained by Thallium-201 scintigraphy. A prolonged 'Mean Rise Time' was indicative of an impairment of myocardial perfusion. We have developed a heart-phase gated real-time digitization procedure and computer-supported method for the densitometric estimation of the MRT to obtain information about the effect of coronary balloon dilatation on myocardial perfusion…
Increased risk of sensory neuropathy in workers with chloracne after exposure to 2,3,7,8-polychlorinated dioxins and furans
Objective - The existence of a peripheral neuropathy after exposure to polychlorinated dioxins (PCDD) is still discussed, as studies concerning dioxin effects on the peripheral nervous system are rare and contradictory. Material and methods - Clinical and neurophysiological examinations (motor conduction velocity of the peroneal nerve, sensory conduction velocities of the sural and ulnar nerves) were made in 156 dioxin exposed workers (42 with, 114 without cloracne) from one pesticide producing plant. Because of known risk factors for peripheral neuropathy, 7 workers with and 28 without cloracne were excluded from further analysis. Results - Workers with chloracne had a significantly higher…
Urticaria, Abdominalschmerzen, Arthritis, Pseudotumor cerebri und nephrotisches Syndrom bei 20jähriger Patientin
Mit 19 Jahren wurde die iranisch-deutsche Patientin im Oktober 1984 wegen einer Coombs-positiven hamolytischen Anamie behandelt. IgG-typische, nichtspezifische Antikorper wurden nachgewiesen. Zuvor war wegen eines grippalen Infektes ein Kombinationsmedikament verordnet worden, das Brompheniramin, Kalziumascorbat, Prophyphenazon, Salizylamid, Chini-din-Hydrochlorid und Coffein (Ilvico®) enthielt. Spezifische Antikorper gegen diese Substanzen waren nicht gesucht worden. Der Coombs-Test blieb 5 Monate positiv. Eine Corticoid-Therapie wurde mit Erfolg klinisch begonnen, von der Patientin wahrscheinlich jedoch nicht konsequent fortgesetzt. Antinukleare Antikorper waren nicht nachweisbar.