0000000000039833

AUTHOR

Cinzia M. Bertea

showing 8 related works from this author

Melatonin and phytomelatonin: Chemistry, biosynthesis, metabolism, distribution and bioactivity in plants and animals—an overview

2021

Melatonin is a ubiquitous indolamine, largely investigated for its key role in the regulation of several physiological processes in both animals and plants. In the last century, it was reported that this molecule may be produced in high concentrations by several species belonging to the plant kingdom and stored in specialized tissues. In this review, the main information related to the chemistry of melatonin and its metabolism has been summarized. Furthermore, the biosynthetic pathway characteristics of animal and plant cells have been compared, and the main differences between the two systems highlighted. Additionally, in order to investigate the distribution of this indolamine in the plan…

N-acetyl-5-methoxytrip-tamineIndolesQH301-705.5Exogenous melatoninReviewN-acetyl-5-methoxytriptamineCatalysisInorganic ChemistryMelatoninchemistry.chemical_compoundCluster analysisIndolamineBiosynthesisSettore BIO/10 - BiochimicamedicineDistribution (pharmacology)AnimalsBiology (General)Physical and Theoretical ChemistryQD1-999Molecular BiologySpectroscopyMelatoninOrganic ChemistryGeneral MedicineMetabolismPlantsPlant cellComputer Science ApplicationsBiostimulantChemistryBiochemistrychemistryDietary Supplementsmedicine.drugBiostimulant; Cluster analysis; Dietary supplements; Indolamine; N-acetyl-5-methoxytrip-tamine
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Phytochemical profile and antioxidative properties of Plinia trunciflora fruits: A new source of nutraceuticals.

2020

Abstract This study evaluated the polyphenol profile and the antioxidative properties of Plinia trunciflora (O. Berg) Kausel fruits. Folin-Ciocalteau and pH-jumping methods indicated that these berries are a major source of antioxidant polyphenols (1201.05 mg GAE/100 g FW), particularly anthocyanins. HPLC-DAD-ESI-MS/MS analysis identified cyanidine glycosides as the main components. Flavon-3-ols and hydrolysable-tannins were also found. CAA assay showed that extracts of P. trunciflora fruits prevent lipid peroxidation in HepG2 cells with higher efficacy than other colourful fruits (CAA50 935.25 mg FW/mL cell medium). Moreover, our results suggested that the observed antioxidant protection i…

AntioxidantDPPHmedicine.medical_treatmentMyrtaceaePhytochemicals01 natural sciencesAntioxidantsAnalytical ChemistryAnthocyaninsLipid peroxidationchemistry.chemical_compoundTandem Mass SpectrometrySettore BIO/10 - BiochimicaFood scienceChromatography High Pressure LiquidChromatographyABTSbiologyChemistryfood and beverages04 agricultural and veterinary sciencesGeneral MedicineHep G2 CellsJaboticaba040401 food scienceUp-RegulationPhytochemicalHigh Pressure LiquidAntioxidant enzymesMyrciaria truncifloraPlinia0404 agricultural biotechnologyNutraceuticalmedicineHumansGlutathione PeroxidasePlant ExtractsSuperoxide DismutaseAntioxidant enzyme010401 analytical chemistryPolyphenolsbiology.organism_classification0104 chemical sciencesPolyphenolFruitDietary SupplementsLipid PeroxidationAnthocyanins; Antioxidant enzymes; Cellular antioxidant activity (CAA); Jaboticaba; Myrciaria trunciflora; Antioxidants; Chromatography High Pressure Liquid; Dietary Supplements; Fruit; Glutathione Peroxidase; Hep G2 Cells; Humans; Lipid Peroxidation; Myrtaceae; Phytochemicals; Plant Extracts; Polyphenols; Superoxide Dismutase; Tandem Mass Spectrometry; Up-RegulationCellular antioxidant activity (CAA)Food ScienceFood chemistry
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Changes in the Phytochemical Profile and Antioxidant Properties of Prunus persica Fruits after the Application of a Commercial Biostimulant Based on …

2022

Plant biostimulants are formulations that are experiencing great success from the perspective of sustainable agriculture. In this work, we evaluated the effect derived from the application of a biostimulant based on algae and yeast extracts (Expando®) on the agronomic yield and nutraceutical profile of two different cultivars (“Sugar Time” and “West Rose”) of Prunus persica (peach). Although, at the agronomic level, significant effects on production yields were not recorded, the biostimulant was able to reduce the ripening time, increase the fruit size, and make the number of harvestable fruits homogeneous. From a nutraceutical point of view, our determinations v…

bioactive compoundscellular antioxidant activityyeast extractsOrganic Chemistryseaweed extractsGeneral Medicineradical scavenging activityCatalysisComputer Science ApplicationsInorganic ChemistryExpando®Settore BIO/10 - Biochimicareducing powerliquid chromatographyPhysical and Theoretical Chemistrybioactive compounds; cellular antioxidant activity; radical scavenging activity; reducing power; polyphenols; liquid chromatography; mass spectrometry; Expando<sup>®</sup>; seaweed extracts; yeast extractsMolecular Biologybioactive compounds; cellular antioxidant activity; radical scavenging activity; reducing power; polyphenols; liquid chromatography; mass spectrometry; Expando®; seaweed extracts; yeast extractsSpectroscopypolyphenolsmass spectrometryInternational Journal of Molecular Sciences; Volume 23; Issue 24; Pages: 15911
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The Application of a Plant Biostimulant Based on Seaweed and Yeast Extract Improved Tomato Fruit Development and Quality

2020

Plant biostimulants are under investigation as innovative products to improve plant production and fruit quality, without resulting in environmental and food contaminations. Here, the effects of the application of Expando, a biostimulant based on seaweed and yeast extracts, on plant productivity, fruit ripening times, and fruit quality of Solanum lycopersicum var. Micro-Tom were evaluated. After biostimulant treatment, a two-week reduction of ripening times and a concomitant enhancement of the production percentage during the earliest ripening times, in terms of both fruit yield (+110%) and size (+85%), were observed. Concerning fruit quality, proximate analysis showed that tomatoes treated…

0106 biological sciencesDPPHPhytochemicalslcsh:QR1-50201 natural sciencesBiochemistryripening timeAntioxidantslcsh:Microbiologychemistry.chemical_compoundSolanum lycopersicumSettore BIO/10 - BiochimicaYeastsSettore BIO/04 - Fisiologia Vegetale0303 health sciencesMineralsABTSbiologyChemistry<i>Solanum lycopersicum</i>carotenoidsfood and beveragesRipeningfruit sizeBioactive compoundLycopeneHorticulturetocopherolsmineral contentArticle03 medical and health sciencesNutraceuticalPicratesYeast extractBenzothiazolesMolecular Biologypolyphenols030304 developmental biologySolanum lycopersicum; carotenoids; fruit quality; fruit size; lycopene; mineral content; polyphenols; ripening time; tocopherolsBiphenyl Compoundsfungifruit qualitybiology.organism_classificationSeaweedlycopeneFruitCarotenoids Fruit quality Lycopene Mineral content Polyphenols Ripening time Solanum lycopersicum TocopherolsSolanumSulfonic Acids010606 plant biology & botany
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Proanthocyanidins and Where to Find Them: A Meta-Analytic Approach to Investigate Their Chemistry, Biosynthesis, Distribution, and Effect on Human He…

2021

Proanthocyanidins (PACs) are a class of polyphenolic compounds that are attracting considerable interest in the nutraceutical field due to their potential health benefits. However, knowledge about the chemistry, biosynthesis, and distribution of PACs is limited. This review summarizes the main chemical characteristics and biosynthetic pathways and the main analytical methods aimed at their identification and quantification in raw plant matrices. Furthermore, meta-analytic approaches were used to identify the main plant sources in which PACs were contained and to investigate their potential effect on human health. In particular, a cluster analysis identified PACs in 35 different plant famili…

endocrine system diseases030309 nutrition & dieteticsPhysiologyClinical Biochemistryforest plotCholesterol; Cluster analysis; Ecology; Forest plot; Hyperglycemia; Hyperlipidemia; Inflammation; Metabolic disorders; Polyphenols; ProanthocyanidinsComputational biologyRM1-950ReviewHealth benefitsBiochemistry03 medical and health sciencesHuman healthSettore BIO/10 - Biochimicahyperlipidemiametabolic disordersMolecular Biologypolyphenols030304 developmental biology0303 health sciencesPotential effectfood and beveragescholesterolCell BiologyinflammationTherapeutics. PharmacologyhyperglycemiaecologyproanthocyanidinsPlant Sourcescluster analysisAntioxidants (Basel, Switzerland)
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Anthocyanins: Biosynthesis, Distribution, Ecological Role, and Use of Biostimulants to Increase Their Content in Plant Foods—A Review

2021

In the past century, plant biostimulants have been increasingly used in agriculture as innovative and sustainable practice. Plant biostimulants have been mainly investigated as potential agents able to mitigate abiotic stress. However, few information is available about their ability to influence fruit quality or change fruit phytochemical composition. In particular, very little is known about their effects on anthocyanin synthesis and accumulation. Due to the increasing demand of consumers for healthier foods with high nutraceutical values, this review tries to fill the gap between anthocyanin content and biostimulant application. Here, we elucidate the chemical structure, biosynthetic pat…

0106 biological sciencesDistribution (economics)antioxidant activityPlant ScienceBiologyPlant foods01 natural sciences03 medical and health scienceschemistry.chemical_compoundNutraceuticalBibliometric analysisSettore BIO/10 - BiochimicaSustainable agricultureSustainable practiceslcsh:Agriculture (General)030304 developmental biologynutraceuticals0303 health sciencesAbiotic stressbusiness.industryfungifruit qualityfood and beveragesphytochemicalslcsh:S1-972Biotechnologysustainable agricultureMeta-analysischemistryAgricultureAnthocyaninbusinessAnthocyanidins; Antioxidant activity; Bibliometric analysis; Fruit quality; Meta-analysis; Nutraceuticals; Phytochemicals; Sustainable agricultureAgronomy and Crop Scienceanthocyanidins010606 plant biology & botanyFood ScienceAgriculture
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Chemical Profile and Biological Activity of Cherimoya (Annona cherimola Mill.) and Atemoya (Annona atemoya) Leaves

2020

Annona cherimola (Cherimoya) and Annona atemoya (Atemoya) are tropical plants known for their edible fruit. Scientific data suggest that their leaves, used in traditional medicine in the form of teas or infusions without evidence of toxicity, contain several bioactive compounds. However, only Annona muricata among all the Annona species is currently used in the nutraceutical field, and its dried leaves are marketed for tea preparation. In this work, we explored the nutraceutical potential of Atemoya and Cherimoya leaves, by evaluating their chemical profile and functional properties. Phytochemical analyses showed large amounts of phenolic compounds, in particular proanthocyanidins, and iden…

antiproliferative activity030309 nutrition & dieteticsPhytochemicalsPharmaceutical ScienceApoptosisAnnona cherimolaalkaloidsArticleAnnonaAnalytical ChemistryHPLC-DAD-MS/MSlcsh:QD241-44103 medical and health sciences0404 agricultural biotechnologyNutraceuticallcsh:Organic chemistrySettore BIO/10 - BiochimicaNeoplasmsDrug DiscoveryTumor Cells CulturedHumansPhysical and Theoretical ChemistryAtemoyaAnnona muricatapolyphenolsCell Proliferation0303 health sciencesbiologyPlant ExtractsOrganic ChemistryAlkaloids; Antioxidants; Antiproliferative activity; HPLC-DAD-MS/MS; Polyphenolsfood and beverages04 agricultural and veterinary sciencesbiology.organism_classification040401 food sciencePlant LeavesSettore BIO/18 - GeneticaHorticultureantioxidantsProanthocyanidinPhytochemicalChemistry (miscellaneous)PolyphenolMolecular MedicineAnnonaMolecules
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Bioactive Compounds and Antioxidant Properties with Involved Mechanisms of Eugenia involucrata DC Fruits

2022

In this study, the phytochemical profile and the antioxidative properties of Eugenia involucrata fruits were evaluated. Spectrophotometric assays indicated that these berries are a rich source of polyphenols with very high radical-scavenging and metal-reducing activities. High-performance liquid chromatography–Orbitrap analysis was able to carry out the annotation of 36 different compounds, mainly belonging to the flavonol, flavan-3-ol, and anthocyanin families. Antioxidant activity of the fruit extract was evaluated in a cell-based lipid peroxidation model. Obtained data showed that the extract, at very low concentration, was able to prevent oxidative damage in HepG2 cells exposed to oxida…

HPLC-OrbitrapPhysiologyABTS; CAA; Cereja-do-Rio-Grande; HPLC-Orbitrap; anthocyanins; antioxidant enzymes; gene expression; oxidative stressClinical BiochemistryCell BiologyBiochemistryanthocyaninsCereja-do-Rio-Grandeantioxidant enzymesSettore BIO/10 - Biochimicagene expressionoxidative stressABTSMolecular BiologyCAA
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