Author: Carl E. Allen

0000000000041163

AUTHOR

Carl E. Allen

BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups.

BRAF-V600E expression is identified in hematopoietic progenitor and precursor myeloid dendritic cells in patients with high-risk LCH, and enforced expression of BRAF-V600E in CD11c+ cells recapitulates a high-risk LCH-like phenotype in mice.

research product

PEPhysical Sciences and Engineering
- PE2Fundamental Constituents of Matter
  - PE2_1Theory of fundamental interactions
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  - PE2_10Atomic, molecular physics
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  - PE2_18Equilibrium and non-equilibrium statistical mechanics: steady states and dynamics
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  - PE2_13Quantum optics and quantum information
  - PE2_15Thermodynamics
- PE1Mathematics
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  - PE1_10ODE and dynamical systems
  - PE1_12Mathematical physics
  - PE1_11Theoretical aspects of partial differential equations
  - PE1_13Probability
  - PE1_14Mathematical statistics
  - PE1_15Generic statistical methodology and modelling
  - PE1_4 Algebraic and complex geometry
  - PE1_19Scientific computing and data processing
  - PE1_2Algebra
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  - PE1_21Application of mathematics in sciences
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  - PE3_1Structure of solids, material growth and characterisation
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  - PE11_8Engineering of alternative established or emergent materials
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LSLife Sciences
- LS1Molecules of Life: Biological Mechanisms, Structures and Functions
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  - LS1_14Innovative methods and modelling in molecular, structural and synthetic biology
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  - LS1_9Molecular mechanisms of signalling processes
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  - LS2_1Genetics
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- LS5Neuroscience and Disorders of the Nervous System
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  - LS5_7Sensory systems, sensation and perception, including pain
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SHSocial Sciences and Humanities
- SH2Institutions, Governance and Legal Systems
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